1,2-Didecanoyl PC

Cayman Chemical Item Number 10009879

Didecanoyl Lecithin; 1,2-Didecanoyl Phosphatidylcholine (CAS 3436-44-0)

1,2-Didecanoyl PC (CAS 3436-44-0)

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Description

Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC is a synthetic, less hydrophobic phospholipis that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of intranasally applied human growth hormone is enhanced when coadministered with the absorption enhancer 1,2-didecanoyl PC.1

1 Agerholm, C., Bastholm, L., Johansen, P.B., et al. Epithelial transport and bioavailability of intranasally administered human growth hormone formulated with the absorption enhancers didecanoyl-L-a-phosphatidylcholine and a-cyclodextrin in rabbits. J Pharm Sci 83(12) 1706-1711 (1994).

Synonyms
  • Didecanoyl Lecithin
  • 1,2-Didecanoyl Phosphatidylcholine
Formal Name 1,​2-​bis(O-​decanoyl)-​sn-​glyceryl-​3-​phosphorylcholine
CAS Number 3436-44-0
Molecular Formula C28H56NO8P
Formula Weight 565.7
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCCCCCC(=O)​OC[C@H]​(COP(=O)​(O)​OCC[N]​(C)​(C)​C)​OC(=O)​CCCCCCCCC
InCHI Code
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​1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)​34-24-26(25-36-38(32,33)​35-23-22-29(3,4)​5)​37-28(31)​21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1
InCHI Key
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MLKLDGSYMHFAOC-AREMUKBSSA-N

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1,2-Didecanoyl PC is available in the following screening library:

Size Price Quantity Subtotal
5 mg $11.00 $0.00
10 mg $21.00 $0.00
25 mg $50.00 $0.00
50 mg $88.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-19. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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