FABP2 Polyclonal Antibody

Cayman Chemical Item Number 10010019

Fatty Acid Binding Protein 2; Intestinal-Fatty Acid Binding Protein; I-FABP

FABP2 Polyclonal Antibody

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Description

Antigen: human FABP2 amino acids 33-40 · Host: rabbit · Application(s): WB; other applications not tested · Fatty acid binding protein 2 (FABP2) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-133 amino acids.1 Members of this protein family exhibit high affinity for small lipophilic ligands and were named according to the tissue from which they were initially isolated. Studies suggest that FABPs are involved in the uptake and metabolism of fatty acids, in the maintenance of cellular membrane fatty acid levels, in intracellular trafficking of these substrates, in the modulation of specific enzymes of lipid metabolic pathways, and in the regulation of cell growth and differentiation.2 FABP family members have highly conserved three dimensional structures and 22-73% amino acid sequence similarity. FABP2 is composed of ten antiparallel β strands that form a barrel that binds ligand in a bent conformation. FABP2 polymorphism has been suggested to be associated with gender specific obesity and increased risk of diabetes.1

1 Zimmerman, A.W., and Veerkamp, J.H. New insights into the structure and function of fatty acid-binding proteins. Cell Mol Life Sci 59 1096-1116 (2002).

2 Massolini, G., and Calleri, E. Survey of binding properties of fatty acid-binding proteins chromatographic methods. J Chromatogr B 797 255-268 (2003).

Synonyms
  • Fatty Acid Binding Protein 2
  • Intestinal-Fatty Acid Binding Protein
  • I-FABP
Formal Name
Formulation Peptide affinity-purified IgG
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human FAPB2 +
Rat FABP2 +
FABP1 -
FABP2 -
FABP3 -
FABP4 -
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Size Price Quantity Subtotal
500 µl $213.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-19. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

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