1-Hexadecyl Lysophosphatidic Acid (sodium salt)

Cayman Chemical Item Number 10010292

Alkyl glycero phosphate 16:0 (sodium salt); 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt); AGP 16:0 (sodium salt)

1-Hexadecyl Lysophosphatidic Acid (sodium salt)

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Description

1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.1 LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.2,3

1 Tsukahara, T., Tsukahara, R., Yasuda, S., et al. Different residues mediate recognition of 1-O-oleyl-lysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ. J Biol Chem 281(6) 3398-3407 (2006).

2 Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends Cell Biol 4 213-219 (1994).

3 Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev 54 265-269 (2002).

Synonyms
  • Alkyl glycero phosphate 16:0 (sodium salt)
  • 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
  • AGP 16:0 (sodium salt)
Formal Name 3-​(hexadecyloxy)-​1-​(dihydrogen phosphate)-​1,​2-​propanediol,​ monosodium salt
Molecular Formula C19H40O6P · Na
Formula Weight 418.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCOC[C@@H]​(O)​COP([O-]​)​(O)​=O.[Na+]​
InCHI Code
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​1S/C19H41O6P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24-17-19(20)​18-25-26(21,22)​23;/h19-20H,2-18H2,1H3,(H2,21,22,23)​;/q;+1/p-1/t19-;/m1./s1
InCHI Key
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KTKBITOTGQCJRQ-FSRHSHDFSA-M

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Size Price Quantity Subtotal
500 µg $17.00 $0.00
1 mg $32.00 $0.00
5 mg $136.00 $0.00
10 mg $238.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-17. Prices are subject to change without notice.

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