1-Hexadecyl Lysophosphatidic Acid (sodium salt)

Cayman Chemical Item Number 10010292

Alkyl glycero phosphate 16:0 (sodium salt); 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt); AGP 16:0 (sodium salt)

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Description

1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.1 LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.2,3

1. Tsukahara, T., Tsukahara, R., Yasuda, S., et al. Different residues mediate recognition of 1-O-oleyl-lysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ. J Biol Chem 281(6) 3398-3407 (2006).

2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends Cell Biol 4 213-219 (1994).

3. Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev 54 265-269 (2002).

Synonyms
  • Alkyl glycero phosphate 16:0 (sodium salt)
  • 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
  • AGP 16:0 (sodium salt)
Formal Name 3-​(hexadecyloxy)-​1-​(dihydrogen phosphate)-​1,​2-​propanediol,​ monosodium salt
Molecular Formula C19H40O6P · Na
Formula Weight 418.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCOC[C@@H]​(O)​COP([O-]​)​(O)​=O.[Na+]​
InCHI Code
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​1S/C19H41O6P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24-17-19(20)​18-25-26(21,22)​23;/h19-20H,2-18H2,1H3,(H2,21,22,23)​;/q;+1/p-1/t19-;/m1./s1
InCHI Key
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KTKBITOTGQCJRQ-FSRHSHDFSA-M

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Size Price Quantity Subtotal
500 µg $17.00 $0.00
1 mg $32.00 $0.00
5 mg $136.00 $0.00
10 mg $238.00 $0.00
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Pricing updated 2015-05-22. Prices are subject to change without notice.

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