Sodium Hydrogen Sulfide (hydrate)

Cayman Chemical Item Number 10012555

NaHS; NSC 158264; Sodium Hydrosulfide (CAS 207683-19-0)

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Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium hydrogen sulfide is an H2S donor commonly used in cellular and whole animal experimental systems. For example, it has been used to suggest that H2S promotes neutrophil migration1, reduces airway inflammation2, and protects neurites,3 heart,4 and intestine5 from chemical or ischemic-reperfusion damage.

1. Dal-Secco, D., Cunha, T.M., Freitas, A., et al. Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: Role of ATP-sensitive potassium channels. J Immunol 181 4287-4298 (2008).

2. Chen, Y., Wu, R., Geng, B., et al. Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. Cytokine 45 117-123 (2009).

3. Hu, L., Lu, M., Wu, Z., et al. Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. Mol Pharmacol 75(1) 27-34 (2009).

4. Yong, Q.C., Lee, S.W., Foo, C.S., et al. Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning. Am J Physiol Heart Circ Physiol 295 H1330-H1340 (2008).

5. Liu, H., Bai, X., Shi, S., et al. Hydrogen sulfide protects from intestinal ischaemia-reperfusion injury in rats. J Pharm Pharmacol 61 207-212 (2009).

  • NaHS
  • NSC 158264
  • Sodium Hydrosulfide
Formal Name sodium sulfide,​ hydrate
CAS Number 207683-19-0
Molecular Formula HNaS · XH2O
Formula Weight 56.1
Formulation A crystalline solid
Purity ≥65%
λmax 224 nm
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
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Size Price Quantity Subtotal
1 g $18.00 $0.00
5 g $81.00 $0.00
10 g $144.00 $0.00
25 g $315.00 $0.00
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Pricing updated 2015-08-01. Prices are subject to change without notice.

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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

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