15-deoxy-Δ12,14-Prostaglandin A1

Cayman Chemical Item Number 10065

15-deoxy-Δ12,14-PGA1 (CAS 573951-20-9)

15-deoxy-Δ12,14-Prostaglandin A1 (CAS 573951-20-9)

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Description

15-deoxy-Δ12,14-Prostaglandin A1 (15-deoxy-Δ12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.1 Antimitotic and antitumor activity have been reported for a similar analog,2 but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA1 at this time.

1 Kliewer, S.A., Lenhard, J.M., Willson, T.M., et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83 813-819 (1995).

2 Kato, T., Fukushima, M., Kurozumi, S., et al. Antitumor activity of Δ7-prostaglandin A1 and Δ12-prostaglandin J2 in vitro and in vivo. Cancer Res 46 3538-3542 (1986).

Synonyms
  • 15-deoxy-Δ12,14-PGA1
Formal Name 9-​oxo-​prosta-​10,​12Z,​14E-​trien-​1-​oic acid
CAS Number 573951-20-9
Molecular Formula C20H30O3
Formula Weight 318.5
Formulation A solution in methyl acetate
Purity >95%
λmax 324 nm
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C/C=C1\C=CC(=O)​C\1CCCCCCC(=O)​O
InCHI Code
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​1S/C20H30O3/c1-2-3-4-5-6-9-12-17-15-16-19(21)​18(17)​13-10-7-8-11-14-20(22)​23/h6,9,12,15-16,18H,2-5,7-8,10-11,13-14H2,1H3,(H,22,23)​/b9-6+,17-12-/t18-/m1/s1
InCHI Key
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LDOCIRJMPUHXRM-YUJGFSRTSA-N

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15-deoxy-Δ12,14-Prostaglandin A1 is available in the following screening libraries:

Size Price Quantity Subtotal
500 µg $78.00 $0.00
1 mg $117.00 $0.00
5 mg $546.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-19. Prices are subject to change without notice.

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