AL 8810 isopropyl ester

Cayman Chemical Item Number 10113

(CAS 208114-93-6)

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AL 8810 is an 11β-fluoro analog of prostaglandin F (PGF) which acts as a potent and selective antagonist at the FP receptor.1 AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost2 and Travoprost.3 The pharmacology of AL 8810 isopropyl ester has not been published.

1. Griffen, B.W., Klimko, P., Crider, J.Y., et al. AL-8810: A novel prostaglandin F analog with selective antagonist effects at the prostaglandin F (FP) receptor. J Pharmacol Exp Ther 290(3) 1278-1284 (1999).

2. Camras, C.B., Alm, A., Watson, P., et al. Latanoprost, a prostaglandin analog, for glaucoma therapy. Efficacy and safety after 1 year of treatment in 198 patients. Ophthalmology 103 1916-1924 (1996).

3. Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future 25 41-45 (2000).

Formal Name 9α,​15R-​dihydroxy-​11β-​fluoro-​15-​(2,​3-​dihydro-​1H-​inden-​2-​yl)-​16,​17,​18,​19,​20-​pentanor-​prosta-​5Z,​13E-​dien-​1-​oic acid,​ isopropyl ester
CAS Number 208114-93-6
Molecular Formula C27H37FO4
Formula Weight 444.6
Formulation A crystalline solid
Purity >98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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AL 8810 isopropyl ester is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $57.00 $0.00
5 mg $257.00 $0.00
10 mg $456.00 $0.00
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Cart Total $0.00

Pricing updated 2015-08-03. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

AL 8810
AL 8810 ethyl amide
AL 8810 methyl ester
Fluprostenol isopropyl ester
Latanoprost (free acid)
Prostaglandin F
(S)-AL 8810
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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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Ann Arbor, Michigan 48108 USA


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