CP 24,879 (hydrochloride)
Cayman Chemical Item Number 10120
Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition. CP 24,879 is an inhibitor of arachidonic acid biosynthesis acting via the inhibition of Δ5/Δ6 desaturase.1 Mice injected with CP 24,879 at 3 mg/kg had a reduction of liver arachidonate content of approximately 50%. Murine mastocytoma cells treated with 5 µM CP 24,879 showed increased mead acid content and nearly complete ablation of leukotriene C4 synthesis, consistent with a desaturase inhibition-
Obukowicz, M.G., Raz, A., Pyla, P.D., et al. Identification and characterization of a novel Δ6/Δ5 fatty acid desaturase inhibitor as a potential anti-
Levin, G., Duffin, K.L., Obukowicz, M.G., et al. Differential metabolism of dihomo-
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CP 24,879 (hydrochloride) is available in the following screening library:
Pricing updated 2015-04-26. Prices are subject to change without notice.
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