13,14-dihydro-15-keto Prostaglandin A2

Cayman Chemical Item Number 10260

13,14-dihydro-15-keto PGA2 (CAS 74872-89-2)

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PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin.1,2 Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2, a stable marker of PGE2 biosynthesis.2

1. Granström, E., Hamberg, M., Hansson, G., et al. Chemical instability of 15-keto-13,14-dihydro-PGE2: The reason for low assay reliability. Prostaglandins 19 933-945 (1980).

2. Fitzpatrick, F.A., Aguirre, R., Pike, J.E., et al. The stability of 13,14-dihydro-15 keto-PGE2. Prostaglandins 19 917-931 (1980).

  • 13,14-dihydro-15-keto PGA2
Formal Name 9,​15-​dioxo-​prosta-​5Z,​10-​dien-​1-​oic acid
CAS Number 74872-89-2
Molecular Formula C20H30O4
Formula Weight 334.5
Formulation A solution in methyl acetate
Purity >98%
λmax 216 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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13,14-dihydro-15-keto Prostaglandin A2 is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $68.00 $0.00
5 mg $306.00 $0.00
10 mg $544.00 $0.00
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Cart Total $0.00

Pricing updated 2015-07-31. Prices are subject to change without notice.

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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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