15(R)-15-methyl Prostaglandin A2

Cayman Chemical Item Number 10270

15(R)-15-methyl PGA2 (CAS 96440-68-5)

15(R)-15-methyl Prostaglandin A2 (CAS 96440-68-5)

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Description

Arbaprostil (15(R)-15-methyl prostaglandin E2) is a synthetic prostaglandin E2 (PGE2) analog developed for its cytoprotective activity.1 15(R)-15-methyl Prostaglandin A2 (15(R)-15-methyl PGA2) is one of several impurities which are possible in the production of commercial lots of bulk arbaprostil.2 The pharmacology and EP receptor binding affinity for 15(R)-15-methyl PGA2 has not been published.

1 Collins, P.W. Misoprostol: Discovery, development, and clinical applications. Med Res Rev 10 149-172 (1990).

2 Kissinger, L.D., and Robins, R.H. Silver-modified mobile phase for normal-phase liquid chromatographic determination of prostaglandins and their 5,6-trans isomers in prostaglandin bulk drugs and triacetin solutions. J Chromatogr 321 353-362 (1985).

Synonyms
  • 15(R)-15-methyl PGA2
Formal Name 9-​oxo-​15R-​hydroxy-​15-​methyl-​prosta-​5Z,​10,​13E-​trien-​1-​oic acid
CAS Number 96440-68-5
Molecular Formula C21H32O4
Formula Weight 348.5
Formulation A solution in methyl acetate
Purity ≥98%
λmax 216 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O=C1[C@H]​(C/C=C\CCCC(O)​=O)​[C@@H]​(/C=C/[C@]​(C)​(O)​CCCCC)​C=C1
InCHI Code
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​1S/C21H32O4/c1-3-4-9-15-21(2,25)​16-14-17-12-13-19(22)​18(17)​10-7-5-6-8-11-20(23)​24/h5,7,12-14,16-18,25H,3-4,6,8-11,15H2,1-2H3,(H,23,24)​/b7-5-,16-14+/t17-,18-,21-/m1/s1
InCHI Key
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UEBXYYKXJUBAJX-ULDSDQABSA-N

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15(R)-15-methyl Prostaglandin A2 is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $43.00 $0.00
5 mg $194.00 $0.00
10 mg $344.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2014-04-18. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

15(R)-15-methyl Prostaglandin E2
Prostaglandin A2
Prostaglandin A2 methyl ester Exclusive

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