CAY10632

Cayman Chemical Item Number 10497

(CAS 105517-82-6)

CAY10632 (CAS 105517-82-6)

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Description

Very long chain polyunsaturated fatty acids (VLCPUFA) are present in retina, sperm, and brain.1,2,3 Though little is known of their biosynthesis or functional roles in these tissues, recent studies using the elongation of very long-chain FA-4 protein suggest a unique role for VLCPUFA in retinal development and macular degeneration.4,5 CAY10632 is a C32:6 VLCPUFA whose specific biological actions are largely unknown, but are thought to involve normal photoreceptor cell function in the retina.4,6

1 Aveldaño, M.I. Phospholipid species containing long and very long polyenoic fatty acids remain with rhodopsin after hexane extraction of photoreceptor membranes. Biochemistry 27 1229-1239 (1988).

2 Robinson, B.S., Johnson, D.W., and Poulos, A. Novel molecular species of spingomyelin containing 2-hydroxylated polyenoic very-long-chain fatty acids in mammalian testes and spermatozoa. J Biol Chem 267 1746-1751 (1992).

3 Robinson, B.S., Johnson, D.W., and Poulos, A. Unique molecular species of phophatidylcholine containing very-long-chain (C24-C38) polyenoic fatty acids in rat brain. Biochem J 265 763-7 (1990).

4 McMahon, A., Jackson, S.N., Woods, A.S., et al. A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32-C36 acyl phosphatidylcholines. FEBS Lett 581 5459-5463 (2007).

5 Agbaga, M., Mandal, M.N.A., and Anderson, R.E. Retinal very long-chain PUFAs: New insights from studies on ELOVL4 protein. J Lipid Res 51 1624-1642 (2010).

6 Agbada, M., Brush, R.S., Mandal, N.A., et al. Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids. Proc Natl Acad Sci USA 105(35) 12843-8 (2008).

Formal Name 14Z,​17Z,​20Z,​23Z,​26Z,​29Z-​dotriacontahexaenoic acid
CAS Number 105517-82-6
Molecular Formula C32H52O2
Formula Weight 468.8
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCCCCCCCCC(O)​=O
InCHI Code
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​1S/C32H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29-30-31-32(33)​34/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-31H2,1H3,(H,33,34)​/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-
InCHI Key
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HIKGLCYKBLODNY-KUBAVDMBSA-N

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Size Price Quantity Subtotal
100 µg $20.00 $0.00
500 µg $90.00 $0.00
1 mg $160.00 $0.00
5 mg $700.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-19. Prices are subject to change without notice.

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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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