(±)-CP 47,497-C8-homolog-d7 (exempt preparation)

Cayman Chemical Item Number 10686

Cannabicyclohexanol-d7

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Description

(±)-CP 47,497-C8-homolog-d7 (exempt preparation) contains seven deuterium atoms at the 6, 6', 7, 7', 8, 8, and 8 positions. It is intended for use as an internal standard for the quantification of (±)-CP 47,497-C8-homolog (exempt preparation) by GC- or LC-mass spectrometry (MS). (±)-CP 47,497-C8-homolog is a bicyclic cannabinoid (CB) analog that avidly binds the CB1 receptor (Ki = 0.83 nM) and shows high antinociceptive activity.1 It is ten-fold more potent than Δ9-tetrahydrocannabinol in analgesic, motor depressant, anticonvulsant, and hypothermic effects in mice.2

1. Melvin, L.S., Milne, G.M., Johnson, M.R., et al. Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: Studies of bicyclic cannabinoid analogs. Mol Pharmacol 44 1008-1015 (1993).

2. Compton, D.R., Johnson, M.R., Melvin, L.S., et al. Pharmacological profile of a series of bicyclic cannabinoid analogs: Classification as cannabimimetic agents. J Pharmacol Exp Ther 260(1) 201-209 (1992).

Synonyms
  • Cannabicyclohexanol-d7
Formal Name rel-​2-​[(1S,​3R)-​3-​hydroxycyclohexyl]-​5-​(2-​methylnonan-​6,​6,​7,​7,​8,​8,​8-​d7-​2-​yl)-​phenol
Molecular Formula C22H29D7O2
Formula Weight 339.6
Formulation A solution in methanol
Purity ≥99% deuterated forms (d1-d7)
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O[C@H]​1C[C@@H]​(C2=CC=C(C(C)​(C)​CCCCC([2H]​)​([2H]​)​C([2H]​)​([2H]​)​C([2H]​)​([2H]​)​[2H]​)​C=C2O)​CCC1
InCHI Code
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​1S/C22H36O2/c1-4-5-6-7-8-14-22(2,3)​18-12-13-20(21(24)​16-18)​17-10-9-11-19(23)​15-17/h12-13,16-17,19,23-24H,4-11,14-15H2,1-3H3/t17-,19+/m0/s1/i1D3,4D2,5D2
InCHI Key
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HNMJDLVMIUDJNH-LQVMWSKMSA-N

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Size Price Quantity Subtotal
100 µg $110.00 $0.00
500 µg $440.00 $0.00
1 mg $660.00 $0.00
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Pricing updated 2015-05-28. Prices are subject to change without notice.

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FAQs

It appears that there is a heterogenous mixture of deuterated species in your deuterated standards; is this normal?

Yes, this is typical of our deuterated products. Our deuterated products contain less than 1 % d0. However, the labeled compounds are not 100% of the deuterated form listed on our product insert. For example, upon analysis of 2-arachidonoyl glycerol-d8 it is expected to see masses associated with the d7, d6, d5 etc.

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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

This product is a DEA exempt preparation of a scheduled compound - no special processing required. For larger quantities or alternate sizes, please contact sales.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

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