Cayman Chemical Item Number 11016

Calcimycin (CAS 52665-69-7)

See more


A-23187 is a divalent cation ionophore. While more selective for Mn2+, it is commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways.1 A-23187 is also used to produce apoptosis through calcium overload, as occurs during hypoxic or oxidative stress.2,3

1. Sullivan, T.J., and Parker, C.W. Pharmacologic modulation of inflammatory mediator release by rat mast cells. Am J Pathol 85(2) 437-464 (1976).

2. Maecker, H.T., Hedjbeli, S., Alzona, M., et al. Comparison of apoptosis signaling through T cell receptor, Fas, and calcium ionophore. Exp Cell Res 222(1) 95-102 (1996).

3. Cho, S., Lee, J., Bae, H., et al. Transglutaminase 2 inhibits apoptosis induced by calcium-overload through down-regulation of Bax. Exp Mol Med 42(9) 639-650 (2010).

  • Calcimycin
Formal Name 5-​(methylamino)-​2-​[[(2R,​3R,​6S,​8S,​9R,​11R)-​3,​9,​11-​trimethyl-​8-​[(1S)-​1-​methyl-​2-​oxo-​2-​(1H-​pyrrol-​2-​yl)ethyl]-​1,​7-​dioxaspiro[5.5]undec-​2-​yl]methyl-​4-​benzoxazolecarboxylic acid
CAS Number 52665-69-7
Molecular Formula C29H37N3O6
Formula Weight 523.6
Formulation A crystalline solid
Purity ≥98%
λmax 226, 279, 379 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Copy SMILES to clipboard
InCHI Code
Copy InCHI code to clipboard
Copy InCHI key to clipboard

Download free InCHI Key generation software

Size Price Quantity Subtotal
1 mg $18.00 $0.00
5 mg $72.00 $0.00
10 mg $92.00 $0.00
25 mg $198.00 $0.00
Bulk Contact
Cart Total $0.00

Pricing updated 2015-07-28. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

Calcium Ionophore I
Neutrophil/Monocyte Respiratory Burst Assay Kit
Show all 9 Hide all but first 3


Batch-specific Information

Get batch-specific data and documents by batch number

Separate multiple batch numbers with commas

Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA


Please wait...