25D-NBOMe (hydrochloride)

Cayman Chemical Item Number 11946

2C-D-NBOMe (CAS 1539266-35-7)

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Description

2C-D (Item No. 11888), a 2,5-dimethoxy phenethylamine, is designer drug with mild hallucinogenic activity, due in part to weak activity at serotonin receptors.1,2 25D-NBOMe is a derivative of 2C-D, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the serotonin receptor 5-HT2A.3,4 This product is intended for research and forensic applications.

1. Meyer, M.R., and Maurer, H.H. Metabolism of designer drugs of abuse: An updated review. Curr Drug Metab 11 468-482 (2010).

2. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. J Pharmacol Exp Ther 321 1054-1061 (2007).

3. Braden, M.R., Parrish, J.C., Naylor, J.C., et al. Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists. Mol Pharm 70(6) 1956-1965 (2006).

4. Ettrup, A., Palner, M., Gillings, N., et al. Radiosysnthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET. J Nuclear Med 51(11) 1763-1770 (2010).

Synonyms
  • 2C-D-NBOMe
Formal Name 2-​(2,​5-​dimethoxy-​4-​methylphenyl)-​N-​(2-​methoxybenzyl)ethanamine,​ monohydrochloride
CAS Number 1539266-35-7
Molecular Formula C19H25NO3 • HCl
Formula Weight 351.9
Formulation A crystalline solid
Purity ≥98%
λmax 203, 220, 282 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CC1=C(OC)​C=C(CCNCC2=C(OC)​C=CC=C2)​C(OC)​=C1.Cl
InCHI Code
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​1S/C19H25NO3.ClH/c1-14-11-19(23-4)​15(12-18(14)​22-3)​9-10-20-13-16-7-5-6-8-17(16)​21-2;/h5-8,11-12,20H,9-10,13H2,1-4H3;1H
InCHI Key
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KJRUHRVUUSGHFU-UHFFFAOYSA-N

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Size Price Quantity Subtotal
1 mg $25.00 $0.00
5 mg $69.00 $0.00
10 mg $95.00 $0.00
50 mg $275.00 $0.00
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Pricing updated 2015-05-05. Prices are subject to change without notice.

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