Prostaglandin D1 Alcohol

Cayman Chemical Item Number 12002

PGD1 Alcohol (CAS 1176470-37-3)

Prostaglandin D1 Alcohol (CAS 1176470-37-3)

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Description

Prostaglandin D1(PGD1) alcohol is the synthetic analog of PGD1 with a primary alcohol in place of the C-1 carboxyl. There are no known reports of its biological activity. PGD1 is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.1

1 Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem 26 790-799 (1983).

Synonyms
  • PGD1 Alcohol
Formal Name 1,​9α,​15S-​trihydroxy-​prost-​13E-​en-​11-​one
CAS Number 1176470-37-3
Molecular Formula C20H36O4
Formula Weight 340.5
Formulation A crystalline solid
Purity >99%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCC(O)​/C=C/[C@H]​1C(=O)​CC(O)​C1CCCCCCCO
InCHI Code
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​1S/C20H36O4/c1-2-3-7-10-16(22)​12-13-18-17(19(23)​15-20(18)​24)​11-8-5-4-6-9-14-21/h12-13,16-19,21-23H,2-11,14-15H2,1H3/b13-12+/t16-,17+,18+,19-/m0/s1
InCHI Key
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SGFHBGFMOSYSBL-KENJKRGESA-N

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Prostaglandin D1 Alcohol is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $51.00 $0.00
5 mg $230.00 $0.00
10 mg $408.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-17. Prices are subject to change without notice.

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