Pricing updated 2015-10-13. Prices are subject to change without notice.
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that plays a key inhibitory role in both the insulin and Wnt signaling pathways.1,2 CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.3 When tested against twenty different protein kinases, this inhibitor shows greater than 500-
|Formulation||A crystalline solid|
WARNING - This product is not for human or veterinary use.
|Shipping||Room temperature in continental US; may vary elsewhere|
Download Product Insert 110 Kb PDF
Download Safety Data Sheet (SDS) 29 Kb PDF
View the Cayman Structure Database for chemical structure definitions for many Cayman products
Separate multiple batch numbers with commas
Sutherland, C., Leighton, I.A., and Cohen, P. Inactivation of glycogen synthase kinase 3β by phosphorylation: New kinase connections in insulin and growth-
Papkoff, J., and Aikawa, M. WNT-
3. Ring, D.B., Johnson, K.W., Henriksen, E.J., et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52(3) 588-95 (2003).
Li, W., Zhou, H., Abujarour, R., et al. Generation of human-
Ying, Q., Wray, J., Nichols, J., et al. The ground state of embryonic stem cell self-
We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.
Cayman is know as a partner to scientists worldwide, responding to your needs with services in: