N-acetyl-D-Glucosamine • NAG; NSC 524344; GlcNAc; Marine Sweet (CAS 7512-17-6) (Inchi key MBLBDJOUHNCFQT-UIYHXYAWSA-N) || Cayman Chemical | Supplier
N-acetyl-D-Glucosamine
Item № 13136
CAS № 7512-17-6
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
500 mg $9.00 $0.00
1 g $17.00 $0.00
5 g $72.00 $0.00
10 g $126.00 $0.00

Pricing updated 2015-09-01. Prices are subject to change without notice.

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Description
Synonyms
  • NAG
  • NSC 524344
  • GlcNAc
  • Marine Sweet

N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer’s disease brain extracts are decreased as compared to that in controls, suggesting that release of GlcNAc may contribute to pathogenesis.1 In E. coli, GlcNAc induces the expression of multidrug exporter genes, indicating that this sugar can alter gene expression.1 GlcNAc is also the monomeric unit of chitin, which is found in fungi and many invertebrates, including crustaceans, insects, and nematodes. For this reason, chemicals that inhibit the incorporation of GlcNAc into chitin are cytotoxic to these organisms.

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Technical Information
Formal Name 2-​(acetylamino)-​2-​deoxy-​D-​glucose
CAS Number 7512-17-6
Synonyms
  • NAG
  • NSC 524344
  • GlcNAc
  • Marine Sweet
Molecular Formula C8H15NO6
Formula Weight 221.2
Purity ≥98%
Formulation A crystalline solid
SMILES O=CC(NC(=O)​C)​C(O)​C(O)​[C@H]​(O)​CO
InChI Code ​1S/C8H15NO6/c1-4(12)​9-5(2-10)​7(14)​8(15)​6(13)​3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)​/t5?,6-,7-,8-/m1/s1
InChI Key MBLBDJOUHNCFQT-UIYHXYAWSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
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Download Product Insert 100 Kb PDF

Download Safety Data Sheet (SDS) 23 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Liu, F., Iqbal, K., Grundke-Iqbal, I., et al. O-GlnNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer’s disease. Proc Natl Acad Sci USA 101(29) 10804-10809 (2004).

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