Neurodazine Exclusive

Cayman Chemical Item Number 13224

(CAS 937807-66-4)

Neurodazine (CAS 937807-66-4)

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Description

Neurodazine induces neuronal differentiation in skeletal muscle cells.1 In mouse C2C12 myoblasts, neurodazine (2 μM for seven days) upregulated the expression of neuron-specific enolase (NSE), neurofilament 200 (NF200), synapsin, and other neuronal markers. Neurodazine similarly upregulated NSE and NF200 in human skeletal muscle fibers, indicating efficacy in mature muscle as well as in myoblasts.

1 Wiliams, D.R., Lee, M., Song, Y., et al. Synthetic small molecules that induce neurogenesis in skeletal muscle. J Am Chem Soc 129 9258-9259 (2007).

Formal Name 2-​[5-​(3-​chlorophenyl)-​2-​furanyl]-​4,​5-​bis(4-​methoxyphenyl)-​1H-​imidazole
CAS Number 937807-66-4
Molecular Formula C27H21ClN2O3
Formula Weight 456.9
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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COc1ccc(cc1)​c1[nH]​c(nc1c1ccc(OC)​cc1)​c1ccc(o1)​c1cccc(Cl)​c1
InCHI Code
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​1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)​25-26(18-8-12-22(32-2)​13-9-18)​30-27(29-25)​24-15-14-23(33-24)​19-4-3-5-20(28)​16-19/h3-16H,1-2H3,(H,29,30)​
InCHI Key
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FEEOFPAEDSMOTO-UHFFFAOYSA-N

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Neurodazine is available in the following screening library:

Size Price Quantity Subtotal
5 mg $77.00 $0.00
10 mg $146.00 $0.00
25 mg $347.00 $0.00
50 mg $616.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-16. Prices are subject to change without notice.

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