ZLJ-6
Item № 13271
CAS № 1051931-39-5
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $31.00 $0.00
5 mg $140.00 $0.00
10 mg $248.00 $0.00
25 mg $543.00 $0.00

Pricing updated 2015-08-28. Prices are subject to change without notice.

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Description

ZLJ-6 is a dual inhibitor of cyclooxygenase (COX) and 5-lipoxygenase (5-LO)(IC50 = 0.73, 0.31, and 0.99 μM for COX-1, COX-2, and 5-LO, respectively, in whole blood).1 It reduces carrageenin-induced paw edema (inflammation) in rats and acetic acid-induced abdominal constriction (pain) in mice without causing gastrointestinal ulcers, a common side effect of non-selective COX inhibitors.

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Technical Information
Formal Name 2-​amino-​1,​5-​dihydro-​1-​methyl-​5-​[[methylsulfonyl)phenyl]methylene]-​4H-​imidazol-​4-​one-​ (methanesulfonate)
CAS Number 1051931-39-5
Molecular Formula C12H13N3O3S · CH3SO3H
Formula Weight 375.4
Purity ≥98%
Formulation A crystalline solid
SMILES O=S(C1=CC=C(/C=C2C(C)​C(N)​=NC/2=O)​C=C1)​(C)​=O.CS(=O)​(O)​=O
InChI Code ​1S/C12H13N3O3S.CH4O3S/c1-15-10(11(16)​14-12(15)​13)​7-8-3-5-9(6-4-8)​19(2,17)​18;1-5(2,3)​4/h3-7H,1-2H3,(H2,13,14,16)​;1H3,(H,2,3,4)​/b10-7-;
InChI Key QEJPXTVPNIOEHZ-VEZAGKLZSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
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Download Product Insert 131 Kb PDF

Download Safety Data Sheet (SDS) 22 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Li, L., Ji, H., Sheng, L., et al. The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. Eur J Pharmacol 607 (1-3) 244-250 (2009).

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