ST638 (CAS 107761-24-0) (Inchi key YKLMGKWXBLSKPK-UHFFFAOYSA-N) || Cayman Chemical | Supplier
ST638
Item № 13337
CAS № 107761-24-0
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $30.00 $0.00
5 mg $135.00 $0.00
10 mg $240.00 $0.00
25 mg $525.00 $0.00

Pricing updated 2015-09-01. Prices are subject to change without notice.

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Description

ST638 is a tyrosine kinase inhibitor (IC50 = 370 nM). It suppresses tyrosine phosphorylation induced by tumor necrosis factor-α and phorbol myristate acetate in neutrophils and by angiotensin II in cardiac fibroblasts.1,2,3

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Technical Information
Formal Name 2-​cyano-​3-​[3-​ethoxy-​4-​hydroxy-​5-​[(5-​phenylthio)methyl]phenyl]-​2-​propenamide
CAS Number 107761-24-0
Molecular Formula C19H18N2O3S
Formula Weight 354.4
Purity ≥98%
Formulation A crystalline solid
SMILES OC1=C(C=C(C=C(C(N)​=O)​C#N)​C=C1OCC)​CSC2=CC=CC=C2
InChI Code ​1S/C19H18N2O3S/c1-2-24-17-10-13(8-14(11-20)​19(21)​23)​9-15(18(17)​22)​12-25-16-6-4-3-5-7-16/h3-10,22H,2,12H2,1H3,(H2,21,23)​
InChI Key YKLMGKWXBLSKPK-UHFFFAOYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
Product Downloads

Download Product Insert 139 Kb PDF

Download Safety Data Sheet (SDS) 25 Kb PDF

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Additional Information

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Inserts
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GCMS Data
References & Background Reading
Product Description References

1. Fuortes, M., Jin, W., and Nathan, C. Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor. J Cell Biol 120(3) 777-784 (1993).

2. Murasawa, S., Mori, Y., Nozawa, Y., et al. Role of calcium-sensitive tyrosine kinase Pyk2/CAKβ/RAFTK in angiotensin II-induced Ras/ERK signaling. Hypertension 32 668-675 (1998).

3. Takemasa, H., Imagawa, N., Kawakami-Honda, N., et al. Effect of phosphotyrosine proteins on phorbol myristate acetate-induced NADPH oxidase activation in guinea pig peritoneal polymorphonuclear leukocytes. Biol Pharm Bull 26(7) 1009-1012 (2003).

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