8-iso Prostaglandin E1

Cayman Chemical Item Number 13360

8-epi PGE1; 8-iso PGE1; Ovinonic acid (CAS 21003-46-3)

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Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin.1 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 µg/ml.2 It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF.3

1. Morrow, J.D., Hill, K.E., Burk, R.F., et al. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA 87 9383-9387 (1990).

2. Taylor, P.L. The 8-isoprostaglandins: Evidence for eight compounds in human semen. Prostaglandins 17 259-267 (1979).

3. Nakano, J., and Kessinger, J.M. Effects of 8-isoprostaglandin E1 on the systemic and pulmonary circulations in dogs. Proc Soc Exp Biol Med 133 1314-1317 (1970).

  • 8-epi PGE1
  • 8-iso PGE1
  • Ovinonic acid
Formal Name 9-​oxo-​11α,​15S-​dihydroxy-​(8β)-​prost-​13E-​en-​1-​oic acid
CAS Number 21003-46-3
Molecular Formula C20H34O5
Formula Weight 354.5
Formulation A light yellow crystalline solid
Purity >98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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8-iso Prostaglandin E1 is available in the following screening libraries:

Size Price Quantity Subtotal
500 µg $37.00 $0.00
1 mg $70.00 $0.00
5 mg $296.00 $0.00
10 mg $518.00 $0.00
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Cart Total $0.00

Pricing updated 2015-07-31. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

8-iso Prostaglandin F
Prostaglandin E1
Prostaglandin F


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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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