Bicyclo Prostaglandin E1
Item № 13530
Purity >98%
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1 mg $70.00 $0.00
5 mg $315.00 $0.00
10 mg $560.00 $0.00

Pricing updated 2015-09-04. Prices are subject to change without notice.

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  • Bicyclo PGE1

Bicyclo Prostaglandin E1 (bicyclo PGE1) is a stable, base-catalyzed transformation product of the PGE1 metabolite 13,14-dihydro-15-keto PGE1. 13,14-dihydro-15-keto PGE1 itself is a metabolite of PGE11,2 found in human plasma at a median level of 10 pg/ml.3 Due to the inherent instability of 13,14-dihydro-15-keto PGE1, it is advisable to quantify it as bicyclo PGE1 to estimate PGE1 biosynthesis or metabolism in vivo.

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Technical Information
Formal Name 11-​deoxy-​13,​14-​dihydro-​15-​keto-​11β,​16.xi.-​cycloprostaglandin E1
  • Bicyclo PGE1
Molecular Formula C20H32O4
Formula Weight 336.5
Purity >98%
Formulation A solution in methyl acetate
SMILES CCCCC1([H]​)​C(CC[C@H]​([C@H]​2CCCCCCC(O)​=O)​[C@@H]​1CC2=O)​=O
InChI Code ​1S/C20H32O4/c1-2-3-8-16-17-13-19(22)​15(14(17)​11-12-18(16)​21)​9-6-4-5-7-10-20(23)​24/h14-17H,2-13H2,1H3,(H,23,24)​/t14-,15-,16?,17+/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 66 Kb PDF

Download Safety Data Sheet (SDS) 30 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Hamberg, M., and Samuelsson, B. On the metabolism of prostaglandins E1 and E2 in man. J Biol Chem 246 6713-6721 (1971).

2. Peskar, B.A., Cawello, W., Rogatti, W., et al. On the metabolism of prostaglandin E1 administered intravenously to human volunteers. J Physiol Pharmacol 42 327-331 (1991).

3. Leonhardt, A., Krauss, M., Gieler, U., et al. In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis. Br J Dermatol 136 337-340 (1997).

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