15-keto Prostaglandin E1

Cayman Chemical Item Number 13680

15-keto PGE1 (CAS 22973-19-9)

15-keto Prostaglandin E1 (CAS 22973-19-9)

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Description

15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE1.1,2

1 Westwick, J. The effect of pulmonary metabolites of prostaglandins E1, E2 and F on ADP-induced aggregation of human and rabbit platelets. Br J Pharmacol 58 297P-298P (1976).

2 Änggård, E. The biological activities of three metabolites of prostaglandin E1. Acta Physiol Scand 66 509-510 (1966).

Synonyms
  • 15-keto PGE1
Formal Name 9,​15-​dioxo-​11α-​hydroxy-​prost-​13E-​en-​1-​oic acid
CAS Number 22973-19-9
Molecular Formula C20H32O5
Formula Weight 352.5
Formulation A solution in methyl acetate
Purity >98%
λmax 229 nm
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCC(=O)​\C=C/[C@H]​1C(O)​CC(=O)​C1CCCCCCC(=O)​O
InCHI Code
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​1S/C20H32O5/c1-2-3-6-9-15(21)​12-13-17-16(18(22)​14-19(17)​23)​10-7-4-5-8-11-20(24)​25/h12-13,16-17,19,23H,2-11,14H2,1H3,(H,24,25)​/b13-12+/t16-,17-,19-/m1/s1
InCHI Key
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VXPBDCBTMSKCKZ-XQHNHVHJSA-N

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15-keto Prostaglandin E1 is available in the following screening libraries:

Size Price Quantity Subtotal
500 µg $52.00 $0.00
1 mg $99.00 $0.00
5 mg $416.00 $0.00
10 mg $728.00 $0.00
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Pricing updated 2014-04-20. Prices are subject to change without notice.

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