15(R)-Prostaglandin E1 • 15(R)-<wbr/>PGE<sub>1</sub>; 15-<wbr/><span class="foreign">epi</span> PGE<sub>1</sub> (CAS 20897-91-0) (Inchi key GMVPRGQOIOIIMI-CHCORRSHSA-N) || Cayman Chemical | Supplier
15(R)-Prostaglandin E1
Item № 13710
CAS № 20897-91-0
Purity ≥95%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $51.00 $0.00
5 mg $230.00 $0.00
10 mg $408.00 $0.00

Pricing updated 2015-09-01. Prices are subject to change without notice.

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Description
Synonyms
  • 15(R)-PGE1
  • 15-epi PGE1

15(R)-PGE1 is the “unnatural” C-15 stereoisomer of PGE1. It is essentially inactive biologically when compared to PGE1.1 It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC50 of 189 µM.2

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Technical Information
Formal Name 9-​oxo-​11α,​15R-​dihydroxy-​prost-​13E-​en-​1-​oic acid
CAS Number 20897-91-0
Synonyms
  • 15(R)-PGE1
  • 15-epi PGE1
Molecular Formula C20H34O5
Formula Weight 354.5
Purity ≥95%
Formulation A solution in methyl acetate
SMILES CCCCC[C@@H]​(O)​/C=C/[C@H]​1C(O)​CC(=O)​C1CCCCCCC(=O)​O
InChI Code ​1S/C20H34O5/c1-2-3-6-9-15(21)​12-13-17-16(18(22)​14-19(17)​23)​10-7-4-5-8-11-20(24)​25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)​/b13-12+/t15-,16-,17-,19-/m1/s1
InChI Key GMVPRGQOIOIIMI-CHCORRSHSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 122 Kb PDF

Download Safety Data Sheet (SDS) 30 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Nakano, J. Relationship between the chemical structure of prostaglandins and their vasoactivities in dogs. Br J Pharmacol 44 63-70 (1972).

2. Jarabak, J., and Braithwaite, S.S. Kinetic studies on a 15-hydroxyprostaglandin dehydrogenase from human placenta. The reaction mechanism and the mechanism of action of various inhibitors.. Arch Biochem Biophys 177 245-254 (1976).

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