16,16-dimethyl Prostaglandin E1

Cayman Chemical Item Number 13750

16,16-dimethyl PGE1 (CAS 41692-15-3)

16,16-dimethyl Prostaglandin E1 (CAS 41692-15-3)

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Description

16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1. It induces human vascular smooth muscle contractions in vitro. It is 2, 3, and 6 times more potent than PGF in contracting tracheal, bronchial, and bronchiolar smooth muscle, respectively.1

1 Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).

Synonyms
  • 16,16-dimethyl PGE1
Formal Name 9-​oxo-​11α,​15R-​dihydroxy-​16,​16-​dimethyl-​prost-​13E-​en-​1-​oic acid
CAS Number 41692-15-3
Molecular Formula C22H38O5
Formula Weight 382.5
Formulation A solution in methyl acetate
Purity >98%
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCCCC(C)​(C)​C(O)​\C=C\[C@H]​1C(O)​CC(=O)​C1CCCCCCC(=O)​O
InCHI Code
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​1S/C22H38O5/c1-4-5-14-22(2,3)​20(25)​13-12-17-16(18(23)​15-19(17)​24)​10-8-6-7-9-11-21(26)​27/h12-13,16-17,19-20,24-25H,4-11,14-15H2,1-3H3,(H,26,27)​/b13-12+/t16-,17-,19-,20-/m1/s1
InCHI Key
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RQOFITYRYPQNLL-ZWSAOQBFSA-N

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16,16-dimethyl Prostaglandin E1 is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $59.00 $0.00
5 mg $266.00 $0.00
10 mg $472.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-17. Prices are subject to change without notice.

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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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