15(S)-15-methyl Prostaglandin E2 Exclusive

Cayman Chemical Item Number 14730

15(S)-15-methyl PGE2 (CAS 35700-27-7)

15(S)-15-methyl Prostaglandin E2 (CAS 35700-27-7)

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Description

15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound.1 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is ten times more potent than PGE1 in contracting uterine smooth muscle.2

1 Robert, A., Schultz, J.R., Nezamis, J.E., et al. Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16,16-dimethyl PGE2. Intravenous, oral and intrajejunal administration. Gastroenterology 70 359-370 (1976).

2 Kimball, F.A., Kirton, K.T., Spilman, C.H., et al. Prostaglandin E1 specific binding in human myometrium. Biol Reprod 13 482-489 (1975).

Synonyms
  • 15(S)-15-methyl PGE2
Formal Name 9-​oxo-​11α,​15S-​dihydroxy-​15-​methyl-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 35700-27-7
Molecular Formula C21H34O5
Formula Weight 366.5
Formulation A solution in methyl acetate
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O[C@H]​1[C@H]​(/C=C/[C@]​(O)​(C)​CCCCC)​[C@@H]​(C/C=C\CCCC(O)​=O)​C(C1)​=O
InCHI Code
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​1S/C21H34O5/c1-3-4-9-13-21(2,26)​14-12-17-16(18(22)​15-19(17)​23)​10-7-5-6-8-11-20(24)​25/h5,7,12,14,16-17,19,23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25)​/b7-5-,14-12+/t16-,17-,19-,21+/m1/s1
InCHI Key
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XSGQFHNPNWBVPT-DSFPJDRCSA-N

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15(S)-15-methyl Prostaglandin E2 is available in the following screening libraries:

Size Price Quantity Subtotal
500 µg $44.00 $0.00
1 mg $84.00 $0.00
5 mg $352.00 $0.00
10 mg $616.00 $0.00
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Pricing updated 2014-04-19. Prices are subject to change without notice.

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