15(S)-15-methyl Prostaglandin E2 Exclusive

Cayman Chemical Item Number 14730

15(S)-15-methyl PGE2 (CAS 35700-27-7)

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Description

15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound.1 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is ten times more potent than PGE1 in contracting uterine smooth muscle.2

1. Robert, A., Schultz, J.R., Nezamis, J.E., et al. Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16,16-dimethyl PGE2. Intravenous, oral and intrajejunal administration. Gastroenterology 70 359-370 (1976).

2. Kimball, F.A., Kirton, K.T., Spilman, C.H., et al. Prostaglandin E1 specific binding in human myometrium. Biol Reprod 13 482-489 (1975).

Synonyms
  • 15(S)-15-methyl PGE2
Formal Name 9-​oxo-​11α,​15S-​dihydroxy-​15-​methyl-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 35700-27-7
Molecular Formula C21H34O5
Formula Weight 366.5
Formulation A solution in methyl acetate
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O[C@H]​1[C@H]​(/C=C/[C@]​(O)​(C)​CCCCC)​[C@@H]​(C/C=C\CCCC(O)​=O)​C(C1)​=O
InCHI Code
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​1S/C21H34O5/c1-3-4-9-13-21(2,26)​14-12-17-16(18(22)​15-19(17)​23)​10-7-5-6-8-11-20(24)​25/h5,7,12,14,16-17,19,23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25)​/b7-5-,14-12+/t16-,17-,19-,21+/m1/s1
InCHI Key
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XSGQFHNPNWBVPT-DSFPJDRCSA-N

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15(S)-15-methyl Prostaglandin E2 is available in the following screening libraries:

Size Price Quantity Subtotal
500 µg $44.00 $0.00
1 mg $84.00 $0.00
5 mg $352.00 $0.00
10 mg $616.00 $0.00
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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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