11-deoxy Prostaglandin F1α • 11-<wbr/>deoxy PGF<sub>1α</sub> (CAS 37785-98-1) (Inchi key HYBPXYQCXNOTFK-DUSCRHDRSA-N) || Cayman Chemical | Supplier
11-deoxy Prostaglandin F
Item № 15512
CAS № 37785-98-1
Purity >99%
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CART TOTAL $0.00
1 mg $42.00 $0.00
5 mg $189.00 $0.00
10 mg $336.00 $0.00

Pricing updated 2015-08-30. Prices are subject to change without notice.

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Description
Synonyms
  • 11-deoxy PGF

11-deoxy PGF is a synthetic analog of PGF. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%.1 11-deoxy PGF is also known to cause rat uterine contractions at a dose 0.3 times that of PGF.2 It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF in guinea pigs.3

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Technical Information
Formal Name 9α,​15S-​dihydroxy-​prost-​13E-​en-​1-​oic acid
CAS Number 37785-98-1
Synonyms
  • 11-deoxy PGF
Molecular Formula C20H36O4
Formula Weight 340.5
Purity >99%
Formulation A crystalline solid
SMILES O[C@@H]​1[C@H]​(CCCCCCC(O)​=O)​[C@@H]​(/C=C/[C@@H]​(O)​CCCCC)​CC1
InChI Code ​1S/C20H36O4/c1-2-3-6-9-17(21)​14-12-16-13-15-19(22)​18(16)​10-7-4-5-8-11-20(23)​24/h12,14,16-19,21-22H,2-11,13,15H2,1H3,(H,23,24)​/b14-12+/t16-,17-,18+,19-/m0/s1
InChI Key HYBPXYQCXNOTFK-DUSCRHDRSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
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Download Product Insert 120 Kb PDF

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Additional Information

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Inserts
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References & Background Reading
Product Description References

1. Lippmann, W. Inhibition of gastric acid secretion in the rat by synthetic prostaglandins. J Pharm Pharmacol 21 335-336 (1969).

2. Broughton, B.J., Caton, M.P.L., Christmas, A.J., et al. Uterine stimulant action of some ω-chain modified (±)-11-deoxyprostaglandins. Prostaglandins 22 53-64 (1981).

3. Hall, D.W.R., and Jaitly, K.D. Structure-activity relationships in a series of 11-deoxy prostaglandins. Prostaglandins 11 573-587 (1976).

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