11-deoxy Prostaglandin F

Cayman Chemical Item Number 15512

11-deoxy PGF (CAS 37785-98-1)

11-deoxy Prostaglandin F1α (CAS 37785-98-1)

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Description

11-deoxy PGF is a synthetic analog of PGF. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%.1 11-deoxy PGF is also known to cause rat uterine contractions at a dose 0.3 times that of PGF.2 It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF in guinea pigs.3

1 Lippmann, W. Inhibition of gastric acid secretion in the rat by synthetic prostaglandins. J Pharm Pharmacol 21 335-336 (1969).

2 Broughton, B.J., Caton, M.P.L., Christmas, A.J., et al. Uterine stimulant action of some ω-chain modified (±)-11-deoxyprostaglandins. Prostaglandins 22 53-64 (1981).

3 Hall, D.W.R., and Jaitly, K.D. Structure-activity relationships in a series of 11-deoxy prostaglandins. Prostaglandins 11 573-587 (1976).

Synonyms
  • 11-deoxy PGF
Formal Name 9α,​15S-​dihydroxy-​prost-​13E-​en-​1-​oic acid
CAS Number 37785-98-1
Molecular Formula C20H36O4
Formula Weight 340.5
Formulation A crystalline solid
Purity >99%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O[C@@H]​1[C@H]​(CCCCCCC(O)​=O)​[C@@H]​(/C=C/[C@@H]​(O)​CCCCC)​CC1
InCHI Code
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​1S/C20H36O4/c1-2-3-6-9-17(21)​14-12-16-13-15-19(22)​18(16)​10-7-4-5-8-11-20(23)​24/h12,14,16-19,21-22H,2-11,13,15H2,1H3,(H,23,24)​/b14-12+/t16-,17-,18+,19-/m0/s1
InCHI Key
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HYBPXYQCXNOTFK-DUSCRHDRSA-N

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11-deoxy Prostaglandin F1α is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $42.00 $0.00
5 mg $189.00 $0.00
10 mg $336.00 $0.00
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Pricing updated 2014-04-21. Prices are subject to change without notice.

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Prostaglandin F

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