17,20-dimethyl Prostaglandin F

Cayman Chemical Item Number 15790

17,20-dimethyl PGF

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17,20-dimethyl PGF is an analog of the limaprost family with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an analog of PGE1 which is orally active in both rats and guinea pigs.1 The additional methyl groups in the lower side chain confer a 10-1,000 fold increase in potency over the parent compound.1 17,20-dimethyl PGF has lower side chain modifications identical to limaprost. There are no published reports describing the pharmacology of 17,20-dimethyl PGF.

1. Tsuboi, T., Hatano, N., Nakatsuji, K., et al. Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an antianginal agent. Arch Int Pharmacodyn 247 89-102 (1980).

  • 17,20-dimethyl PGF
Formal Name 9α,​11α,​15S-​trihydroxy-​17S,​20-​dimethyl-​prost-​13E-​en-​1-​oic acid
Molecular Formula C22H40O5
Formula Weight 384.6
Formulation A crystalline solid
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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17,20-dimethyl Prostaglandin F is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $51.00 $0.00
5 mg $230.00 $0.00
10 mg $408.00 $0.00
25 mg $893.00 $0.00
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Cart Total $0.00

Pricing updated 2015-08-01. Prices are subject to change without notice.

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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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Ann Arbor, Michigan 48108 USA


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