Prostaglandin F Alcohol
Item № 16012
CAS № 13261-27-3
Purity ≥98%
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1 mg $41.00 $0.00
5 mg $230.00 $0.00
10 mg $408.00 $0.00

Pricing updated 2015-11-27. Prices are subject to change without notice.

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  • AGN 190190
  • PGF-OH
  • ZK 62717

Prostaglandin F alcohol (PGF-OH) is an analog of PGF in which the C-1 carboxyl group has been reduced to a primary alcohol. Biological studies on rat uterus show it to be a weak agonist.1 The compound is reported to retain ocular hypotensive properties,2 but the nature of the receptors which mediate these effects is disputed.3

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Technical Information
Formal Name 1,9α,11α,15S-tetrahydroxyprosta-5Z,13E-diene
CAS Number 13261-27-3
  • AGN 190190
  • PGF-OH
  • ZK 62717
Molecular Formula C20H36O4
Formula Weight 340.5
Purity ≥98%
Formulation A solution in methyl acetate
SMILES O[C@@H]1[C@H](C/C=C\CCCCO)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChI Code 1S/C20H36O4/c1-2-3-7-10-16(22)12-13-18-17(19(23)15-20(18)24)11-8-5-4-6-9-14-21/h5,8,12-13,16-24H,2-4,6-7,9-11,14-15H2,1H3/b8-5-,13-12+/t16-,17+,18+,19-,20+/m0/s1

WARNING - This product is not for human or veterinary use.

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Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
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Download Product Insert 75 Kb PDF

Download Safety Data Sheet (SDS) 31 Kb PDF

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References & Background Reading
Product Description References

1. Brambaifa, N. Luteolytic potency of PGD and PGF derivatives. Eur J Obstet Gynecol Reprod Biol 27 319-325 (1988).

2. Woodward, D.F., and Chan, M.F. Preparation of PGF-1 alcohols as ocular hypotensives. 38204 1-12 (1993).

3. Woodward, D.F., Krauss, A.H., Chen, J., et al. Replacement of the carboxylic acid group of prostaglandin F with a hydroxyl or methoxy substituent provides biologically unique compounds. Br J Pharmacol 130 1933-1943 (2000).

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