Prostaglandin F Alcohol

Cayman Chemical Item Number 16012

AGN 190190; PGF-OH; ZK 62717 (CAS 13261-27-3)

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Prostaglandin F alcohol (PGF-OH) is an analog of PGF in which the C-1 carboxyl group has been reduced to a primary alcohol. Biological studies on rat uterus show it to be a weak agonist.1 The compound is reported to retain ocular hypotensive properties,2 but the nature of the receptors which mediate these effects is disputed.3

1. Brambaifa, N. Luteolytic potency of PGD and PGF derivatives. Eur J Obstet Gynecol Reprod Biol 27 319-325 (1988).

2. Woodward, D.F., and Chan, M.F. Preparation of PGF-1 alcohols as ocular hypotensives. 38204 1-12 (1993).

3. Woodward, D.F., Krauss, A.H., Chen, J., et al. Replacement of the carboxylic acid group of prostaglandin F with a hydroxyl or methoxy substituent provides biologically unique compounds. Br J Pharmacol 130 1933-1943 (2000).

  • AGN 190190
  • PGF-OH
  • ZK 62717
Formal Name 1,​9α,​11α,​15S-​tetrahydroxyprosta-​5Z,​13E-​diene
CAS Number 13261-27-3
Molecular Formula C20H36O4
Formula Weight 340.5
Formulation A solution in methyl acetate
Purity >98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
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Prostaglandin F Alcohol is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $41.00 $0.00
5 mg $230.00 $0.00
10 mg $408.00 $0.00
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Cart Total $0.00

Pricing updated 2015-07-28. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA


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