Prostaglandin F Alcohol methyl ether
Item № 16014
CAS № 143656-18-2
Purity >98%
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1 mg $51.00 $0.00
5 mg $230.00 $0.00
10 mg $408.00 $0.00

Pricing updated 2015-09-03. Prices are subject to change without notice.

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  • AGN 191129
  • PGF-OMe

Prostaglandin F alcohol methyl ether (PGF-OMe) is an analog of PGF in which the C-1 carboxyl group has been replaced an O-methyl ether. The compound is reported to retain ocular hypotensive properties,1 but the receptors which mediate this activity have not been clearly documented.2

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Technical Information
Formal Name 1-​methoxy-​9α,​11α,​15S-​trihydroxyprosta-​5Z,​13E-​diene
CAS Number 143656-18-2
  • AGN 191129
  • PGF-OMe
Molecular Formula C21H38O4
Formula Weight 354.5
Purity >98%
Formulation A solution in methyl acetate
SMILES O[C@@H]​1[C@H]​(C/C=C\CCCCOC)​[C@@H]​(/C=C/[C@@H]​(O)​CCCCC)​[C@H]​(O)​C1
InChI Code ​1S/C21H38O4/c1-3-4-8-11-17(22)​13-14-19-18(20(23)​16-21(19)​24)​12-9-6-5-7-10-15-25-2/h6,9,13-14,17-24H,3-5,7-8,10-12,15-16H2,1-2H3/b9-6-,14-13+/t17-,18+,19+,20-,21+/m0/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
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References & Background Reading
Product Description References

1. Woodward, D.F., and Chan, M.F. Preparation of PGF-1 alcohols as ocular hypotensives. 38204 1-12 (1993).

2. Woodward, D.F., Krauss, A.H., Chen, J., et al. Replacement of the carboxylic acid group of prostaglandin F with a hydroxyl or methoxy substituent provides biologically unique compounds. Br J Pharmacol 130 1933-1943 (2000).

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