Pricing updated 2015-10-04. Prices are subject to change without notice.
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor.1,2,3 Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-
|Immunogen||human DcR2 precursor amino acids 249-
|Formulation||100 µg affinity-
WARNING - This product is not for human or veterinary use.
|Shipping||Wet ice in continental US; may vary elsewhere|
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1. Pan, G., O'Rourke, K., Chinnaiyan, A.M., et al. The receptor for the cytotoxic ligand TRAIL. Science 276 111-113 (1997).
Pan, G., Ni, J., Wei, Y., et al. An antagonist decoy receptor and a death domain-
Sheridan, J.P., Marsters, S.A., Pitti, R.M., et al. Control of TRAIL-
4. Marsters, S.A., Sheridan, J.P., Pitti, R.M., et al. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol 7 1003-1006 (1997).
6. Pan, G., Ni, J., Yu, G., et al. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling. FEBS Lett 424 41-45 (1998).
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