15-keto Prostaglandin F
Item № 16720
CAS № 35850-13-6
Purity ≥98%
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1 mg $53.00 $0.00
5 mg $239.00 $0.00
10 mg $424.00 $0.00

Pricing updated 2015-11-29. Prices are subject to change without notice.

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  • 15-keto PGF

15-keto Prostaglandin F (15-keto PGF) is the first metabolite of PGF. in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone.1,2 15-keto PGF stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively.1,2 15-keto PGF is 10-fold less active than PGF in decreasing rabbit intraocular pressure.3

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Technical Information
Formal Name 9α,11α-dihydroxy-15-oxo-prosta-5Z,13E-dien-1-oic acid
CAS Number 35850-13-6
  • 15-keto PGF
Molecular Formula C20H32O5
Formula Weight 352.5
Purity ≥98%
Formulation A solution in methyl acetate
λmax 234 nm
SMILES O[C@H]1[C@H](/C=C/C(CCCCC)=O)[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C1
InChI Code 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,16-19,22-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t16-,17-,18+,19-/m1/s1

WARNING - This product is not for human or veterinary use.

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Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
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References & Background Reading
Product Description References

1. Sorensen, P.W., Hara, T.J., Goetz, F.W., et al. F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. Biol Reprod 39 1039-1050 (1988).

2. Moore, A., and Waring, C.P. Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar) PARR. J Exp Biol 199 2307-2316 (1996).

3. Woodward, D.F., Williams, L.S., and Chen, J. Marked differential effects of prostanoid metabolites on rabbit intraocular pressure. Ophthalmic Res 21 428-435 (1989).

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