17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α • 17-<wbr/>trifluoromethylphenyl-<wbr/>13,14-<wbr/>dihydro trinor PGF<sub>2α</sub> (CAS 294856-01-2) (Inchi key GGAGMUSEFHEEBF-XPRPYWGDSA-N) || Cayman Chemical | Supplier
17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F
Item № 16895
CAS № 294856-01-2
Purity ≥98%
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $56.00 $0.00
5 mg $252.00 $0.00
10 mg $448.00 $0.00

Pricing updated 2015-09-01. Prices are subject to change without notice.

Bulk Inquiry Form

X

Enter number, size, and select unit. Example: 2 x 500 mg

Please indicate any analytical testing requirements, special handling, packaging, or delivery requirements.

Description
Synonyms
  • 17-trifluoromethylphenyl-13,14-dihydro trinor PGF

A number of 17-phenyl trinor prostaglandin F (17-phenyl trinor PGF) derivatives have been approved for the treatment of glaucoma.1,2,3 Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.4 17-trifluoromethylphenyl-13,14-dihydro trinor PGF bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF would act very much like the free acid of latanoprost.

Download Product Insert Download Safety Data Sheet (SDS)

Related Products

Show all 7 Hide all but first 3

View Related Product Categories
View Screening Libraries with 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F
Technical Information
Formal Name 9α,​11α,​15R-​trihydroxy-​17-​(3-​(trifluoromethyl)phenyl)-​18,​19,​20-​trinor-​prosta-​5Z-​en-​1-​oic acid
CAS Number 294856-01-2
Synonyms
  • 17-trifluoromethylphenyl-13,14-dihydro trinor PGF
Molecular Formula C24H33O5F3
Formula Weight 458.5
Purity ≥98%
Formulation A solution in methyl acetate
SMILES O[C@@H]​1[C@H]​(C/C=C\CCCC(O)​=O)​[C@@H]​(CC[C@@H]​(O)​CCC2=CC(C(F)​(F)​F)​=CC=C2)​[C@H]​(O)​C1
InChI Code ​1S/C24H33F3O5/c25-24(26,27)​17-7-5-6-16(14-17)​10-11-18(28)​12-13-20-19(21(29)​15-22(20)​30)​8-3-1-2-4-9-23(31)​32/h1,3,5-7,14,18-22,28-30H,2,4,8-13,15H2,(H,31,32)​/b3-1-/t18-,19+,20+,21-,22+/m0/s1
InChI Key GGAGMUSEFHEEBF-XPRPYWGDSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
Product Downloads

Download Product Insert 128 Kb PDF

Download Safety Data Sheet (SDS) 31 Kb PDF

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Separate multiple batch numbers with commas

Inserts
QC Sheets
Certificates of Analysis
GCMS Data
References & Background Reading
Product Description References

1. Woodward, D.F., Krauss, A.H., Chen, J., et al. The pharmacology of Bimatoprost (Lumigan™). Surv Ophthalmol 45 S337-S345 (2001).

2. Stjernschantz, J.W. From PGF-isopropyl ester to latanoprost: A review of the development of xalatan. The proper lecture. Invest Ophthamol Vis Sci 42(6) 1134-1145 (2001).

3. Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future 25 41-45 (2000).

4. Resul, B., Stjernschantz, J., No, K., et al. Phenyl-substituted prostaglandins: Potent and selective antiglaucoma agents. J Med Chem 36 243-248 (1993).

Technical Support
Contact Us
  • To streamline the process attach the appropriate questionnaire to your inquiry.

  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Contract Research Services

We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.

Cayman is know as a partner to scientists worldwide, responding to your needs with services in:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

JOIN OUR SOCIAL NETWORK!

Please wait...