(±)9-HODE
Item № 38400
CAS № 98524-19-7
Purity ≥98%
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CART TOTAL $0.00
100 µg $76.00 $0.00
500 µg $342.00 $0.00
1 mg $608.00 $0.00

Pricing updated 2015-09-05. Prices are subject to change without notice.

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Description

(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes.1,2 Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs and HODEs.3,4

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Technical Information
Formal Name (±)-​9-​hydroxy-​10E,​12Z-​octadecadienoic acid
CAS Number 98524-19-7
Molecular Formula C18H32O3
Formula Weight 296.5
Purity ≥98%
Formulation A solution in ethanol
λmax 234 nm
SMILES CCCCC/C=C\C=C/C(O)​CCCCCCCC(=O)​O
InChI Code ​1S/C18H32O3/c1-2-3-4-5-6-8-11-14-17(19)​15-12-9-7-10-13-16-18(20)​21/h6,8,11,14,17,19H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)​/b8-6-,14-11+
InChI Key NPDSHTNEKLQQIJ-ZJHFMPGASA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 126 Kb PDF

Download Safety Data Sheet (SDS) 28 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Kühn, H., Belkner, J., and Wiesner, R. Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes. Eur J Biochem 191 221-227 (1990).

2. Kühn, H., Belkner, J., and Wiesner, R. Metabolism of polyenoic fatty acids by rabbit reticulocytes. Intracellular action of the erythroid lipoxygenase on membrane lipids. Biomed Biochim Acta 49 S25-S30 (1990).

3. Folcik, V.A., and Cathcart, M.K. Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL. J Lipid Res 35 1570-1582 (1994).

4. Ku, G., Thomas, C.E., Akeson, A.L., et al. Induction of interleukin 1β expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid. J Biol Chem 267 14183-14188 (1992).

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