2-O-methyl PAF C-16

Cayman Chemical Item Number 60902

(CAS 78858-44-3)

See more

Description

2-O-methyl PAF C-16 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. Although the biological activities of 2-O-methyl PAF C-16 have not been well characterized, the C-18 analog has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.1 In rat astrocytes, the C-18 analog causes the release of large quantities of NO by a pathway involving activation of NOS.2

1. van Blitterswijk, W.J., Hilkmann, H., and Storme, G.A. Accumulation of an alkyl lysophospholipid in tumor cell membranes affects membrane fluidity and tumor cell invasion. Lipids 22 820-823 (1987).

2. Cardile, V., Jiang, X., Renis, M., et al. Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero-3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytes. Brain Res 715 98-103 (1996).

Formal Name 1-​O-​hexadecyl-​2-​O-​methyl-​sn-​glyceryl-​3-​phosphorylcholine
CAS Number 78858-44-3
Molecular Formula C25H54NO6P
Formula Weight 495.7
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
CCCCCCCCCCCCCCCCOC[C@@H]​(OC)​COP(OCC[N+]​(C)​(C)​C)​([O-]​)​=O
InCHI Code
Copy InCHI code to clipboard
​1S/C25H54NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-30-23-25(29-5)​24-32-33(27,28)​31-22-20-26(2,3)​4/h25H,6-24H2,1-5H3
InCHI Key
Copy InCHI key to clipboard
RZNRKXGAJMGLIM-UHFFFAOYSA-N

Download free InCHI Key generation software

2-O-methyl PAF C-16 is available in the following screening library:

Size Price Quantity Subtotal
5 mg $46.00 $0.00
10 mg $87.00 $0.00
50 mg $368.00 $0.00
100 mg $644.00 $0.00
Bulk Contact
Cart Total $0.00

Bulk Inquiry Form:

Thank you for requesting a bulk size for this product.










X

Enter number, size, and select unit. Example: 2 x 500 mg




Please indicate any analytical testing requirements, special handling, packaging, or delivery requirements.

Pricing updated 2015-04-19. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

PAF C-16
PAF C-16 Carboxylic Acid Exclusive

Downloads

Batch-specific Information

Get batch-specific data and documents by batch number


Separate multiple batch numbers with commas

Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

JOIN OUR SOCIAL NETWORK!

Please wait...

Lost password?