Arachidonoyl PAF C-16

Cayman Chemical Item Number 60904

1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine (CAS 86288-11-1)

Arachidonoyl PAF C-16 (CAS 86288-11-1)

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Description

Arachidonoyl PAF C-16 is the product of acylation of lyso-PAF C-16 by a CoA-independent transacylase.1,2 It is the most common precursor for formation of PAF C-16 by the remodeling pathway.3

1 Kramer, R.M., Patton, G.M., Pritzker, C.R., et al. Metabolism of platelet-activating factor in human platelets. J Biol Chem 259 13316-13320 (1984).

2 Venable, M.E., Olson, S.C., Nieto, M.L., et al. Enzymatic studies of lyso platelet-activation factor acylation in human neutrophils and changes upon stimulation. J Biol Chem 268 7965-7975 (1993).

3 Prescott, S.M., Zimmerman, G.A., and McIntyre, T.M. Platelet-activating factor. J Biol Chem 265 17381-17384 (1990).

Synonyms
  • 1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine
Formal Name 1-​O-​hexadecyl-​2-​O-​(5Z,​8Z,​11Z,​14Z-​eicosatetraenoyl)-​sn-​glyceryl-​3-​phosphorylcholine
CAS Number 86288-11-1
Molecular Formula C44H82NO7P
Formula Weight 768.1
Formulation A solution in ethanol containing 0.1% BHT
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H]​(COP([O-]​)​(OCC[N+]​(C)​(C)​C)​=O)​COCCCCCCCCCCCCCCCC)​=O
InCHI Code
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​1S/C44H82NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-27-29-31-33-35-37-44(46)​52-43(42-51-53(47,48)​50-40-38-45(3,4)​5)​41-49-39-36-34-32-30-28-26-21-19-17-15-13-11-9-7-2/h14,16,20,22,24-25,29,31,43H,6-13,15,17-19,21,23,26-28,30,32-42H2,1-5H3/b16-14-
InCHI Key
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DUUSFCFZBREELS-WWBBCYQPSA-N

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Arachidonoyl PAF C-16 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $39.00 $0.00
5 mg $176.00 $0.00
10 mg $312.00 $0.00
25 mg $683.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-16. Prices are subject to change without notice.

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