Eicosapentaenoyl PAF C-16

Cayman Chemical Item Number 60907

(CAS 132196-28-2)

Eicosapentaenoyl PAF C-16 (CAS 132196-28-2)

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Description

Eicosapentaenoyl PAF C-16 can be formed by incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, as has been demonstrated using neutrophils from monkeys and humans fed a diet enriched in fish oils.1,2 Eicosapentaenoyl PAF C-16 can serve as a substrate for PAF C-16 formation by the remodeling pathway.2

1 Chabot, M.C., Schmitt, J.D., Bullock, B.C., et al. Reacylation of platelet activating factor with eicosapentaenoic acid in fish-oil-enriched monkey neutrophils. Biochim Biophys Acta 922 214-220 (1987).

2 Triggiani, M., Connell, T.R., and Chilton, F.H. Evidence that increasing the cellular content of eicosapentaenoic acid does not reduce the biosynthesis of platelet-activating factor. J Immunol 145 2241-2248 (1990).

Formal Name 1-​O-​hexadecyl-​2-​O-​(5Z,​8Z,​11Z,​14Z,​17Z-​eicosapentaenoyl)-​sn-​glyceryl-​3-​phosphorylcholine
CAS Number 132196-28-2
Molecular Formula C44H80NO7P
Formula Weight 766.1
Formulation Solution in ethanol with 0.1% BHT
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H]​(COP(OCC[N+]​(C)​(C)​C)​([O-]​)​=O)​COCCCCCCCCCCCCCCCC)​=O
InCHI Code
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​1S/C44H80NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-27-29-31-33-35-37-44(46)​52-43(42-51-53(47,48)​50-40-38-45(3,4)​5)​41-49-39-36-34-32-30-28-26-21-19-17-15-13-11-9-7-2/h8,10,14,16,20,22,24-25,29,31,43H,6-7,9,11-13,15,17-19,21,23,26-28,30,32-42H2,1
InCHI Key
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YHSSHPWVFALMBA-IARQOZKNSA-N

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Eicosapentaenoyl PAF C-16 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $39.00 $0.00
5 mg $176.00 $0.00
10 mg $312.00 $0.00
25 mg $683.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-17. Prices are subject to change without notice.

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