Pyrrolidino PAF C-16

Cayman Chemical Item Number 60909

(CAS 91021-63-5)

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Description

Pyrrolidino PAF C-16 is a synthetic analog of PAF C-16. It is a potent mediator of PAF-like activities, including hypotension1,2 and platelet aggregation, where it is approximately 3-10 times more potent than PAF itself.1,2

1. Shigenobu, K., Masuda, Y., Tanaka, Y., et al. Platelet activating factor analogues: Lack of correlation between their activities to produce hypotension and endothelium-mediated vasodilation. J Pharmacobiodyn 8 128-133 (1985).

2. Kasuya, Y., Masuda, Y., and Shigenobu, K. Hypotensive actions of some analogues of platelet-activating factor (PAF) with higher potencies than natural PAF. Can J Physiol Pharmacol 62 457-459 (1984).

Formal Name 1-​O-​hexadecyl-​2-​O-​acetyl-​sn-​glyceryl-​3-​phosphoryl-​N-​methyl-​pyrrolidinium ethanol
CAS Number 91021-63-5
Molecular Formula C28H56NO7P
Formula Weight 549.7
Formulation A lyophilized powder
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCOC[C@@H]​(OC(C)​=O)​COP(OCC[N+]​1(C)​CCCC1)​([O-]​)​=O
InCHI Code
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​1S/C28H56NO7P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-19-23-33-25-28(36-27(2)​30)​26-35-37(31,32)​34-24-22-29(3)​20-17-18-21-29/h28H,4-26H2,1-3H3/t28-/m1/s1
InCHI Key
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QBLLCUIJMABRFJ-MUUNZHRXSA-N

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Pyrrolidino PAF C-16 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $39.00 $0.00
5 mg $176.00 $0.00
10 mg $312.00 $0.00
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PAF C-16

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