Hexadecyl Acetyl Glycerol

Cayman Chemical Item Number 60920

HAG (CAS 77133-35-8)

Hexadecyl Acetyl Glycerol (CAS 77133-35-8)

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Description

Hexadecyl acetyl glycerol (HAG) is an analog of DAG, which inhibits the activation of PKC by DAG.1 It also inhibits the growth of HL-60 cells and induces differentiation to cells resembling mononuclear phagocytes. Following treatment with 5 µg/ml HAG for six days, HL-60 cells demonstrated a 10-fold increase in non-specific esterase activity.2

1 Daniel, L.W., Small, G.W., and Schmitt, J.D. Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols. Biochem Biophys Res Commun 151 291-297 (1988).

2 McNamara, M.J.C., Schmitt, J.D., Wykle, R.L., et al. 1-O-Hexadecyl-2-acetyl-sn-glycerol stimulates differentiation of HL-60 human promyelocytic leukemia cells to macrophage-like cells. Biochem Biophys Res Commun 122 824-830 (1984).

Synonyms
  • HAG
Formal Name 1-​O-​hexadecyl-​2-​O-​acetyl-​sn-​glycerol
CAS Number 77133-35-8
Molecular Formula C21H42O4
Formula Weight 358.6
Formulation A solution in acetonitrile
Purity ≥90%
Stability 6 months
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCOC[C@H]​(CO)​OC(=O)​C
InCHI Code
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​1S/C21H42O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24-19-21(18-22)​25-20(2)​23/h21-22H,3-19H2,1-2H3/t21-/m0/s1
InCHI Key
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QTEHGUUSIIWOOW-NRFANRHFSA-N

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Hexadecyl Acetyl Glycerol is available in the following screening library:

Size Price Quantity Subtotal
5 mg $39.00 $0.00
10 mg $74.00 $0.00
50 mg $312.00 $0.00
100 mg $546.00 $0.00
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Pricing updated 2014-04-19. Prices are subject to change without notice.

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