2-O-ethyl PAF C-16 (CAS 78858-42-1) (Inchi key LPHUUVMLQFHHQG-UHFFFAOYSA-N) || Cayman Chemical | Supplier
2-O-ethyl PAF C-16
Item № 60925
CAS № 78858-42-1
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
5 mg $50.00 $0.00
10 mg $90.00 $0.00
50 mg $405.00 $0.00
100 mg $730.00 $0.00

Pricing updated 2015-09-01. Prices are subject to change without notice.

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Description

2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP.1 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.2

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Technical Information
Formal Name 1-​O-​hexadecyl-​2-​O-​ethyl-​sn-​glyceryl-​3-​phosphorylcholine
CAS Number 78858-42-1
Molecular Formula C26H56NO6P
Formula Weight 509.7
Purity ≥98%
Formulation A lyophilized powder
SMILES CCCCCCCCCCCCCCCCOC[C@@H]​(OCC)​COP(OCC[N+]​(C)​(C)​C)​([O-]​)​=O
InChI Code ​1S/C26H56NO6P/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-20-22-30-24-26(31-7-2)​25-33-34(28,29)​32-23-21-27(3,4)​5/h26H,6-25H2,1-5H3
InChI Key LPHUUVMLQFHHQG-UHFFFAOYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
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Download Product Insert 77 Kb PDF

Download Safety Data Sheet (SDS) 24 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Hadváry, P., Cassal, J., Hirth, G., et al. Structural requirements for the activation of blood platelets by analogues of platelet-activating factor (PAF-acether). Platelet-Activating Factor INSERM Symposium 23 57-64 (1983).

2. O'Flaherty, J.T., Lees, C.J., Miller, C.H., et al. Selective desensitization of neutrophils: Further studies with 1-O-alkyl-sn-glycero-3-phosphocholine analogues. J Immunol 127 731-737 (1981).

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