Cayman Chemical Item Number 62580
Fumonisin B1 is a mycotoxin produced from F. moniliforme, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins.1 It functions as an inhibitor of ceramide synthase (sphingosine N-
Gelderblom, W.C.A., Jaskiewicz, K., Marasas, W.F.O., et al. Fumonisins -
2. Wang, E., Norred, W.P., Bacon, C.W., et al. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J Biol Chem 266 14486-14490 (1991).
3. Balsinde, J., Balboa, M.A., and Dennis, E.A. Inflammatory activation of arachidonic acid signaling in murine P388D1 macrophages via sphingomyelin synthesis. J Biol Chem 272 20373-20377 (1997).
Wieder, T., Orfanos, C.E., and Geilen, C.C. Induction of ceramide-
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Fumonisin B1 is available in the following screening library:
Pricing updated 2015-03-31. Prices are subject to change without notice.
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