S-Farnesyl Thioacetic Acid • FTA (CAS 135784-48-4) (Inchi key GNWWFEVBHYESNK-XGGJEREUSA-N) || Cayman Chemical | Supplier
S-Farnesyl Thioacetic Acid
Item № 63260
CAS № 135784-48-4
Purity ≥97%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $14.00 $0.00
5 mg $63.00 $0.00
10 mg $112.00 $0.00
50 mg $490.00 $0.00

Pricing updated 2015-09-01. Prices are subject to change without notice.

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Description
Synonyms
  • FTA

S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine which behaves as a competitive inhibitor of isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). It can also inhibit methylation of both farnesylated and geranylgeranylated substrates.1,2,3

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Technical Information
Formal Name (3,​7,​11-​trimethyl-​2E,​6E,​10-​dodecatrienyl)thioacetic acid
CAS Number 135784-48-4
Synonyms
  • FTA
Molecular Formula C17H28O2S
Formula Weight 296.5
Purity ≥97%
Formulation A solution in ethanol
SMILES C/C(C)​=C/CC/C(C)​=C/CC/C(C)​=C/CSCC(O)​=O
InChI Code ​1S/C17H28O2S/c1-14(2)​7-5-8-15(3)​9-6-10-16(4)​11-12-20-13-17(18)​19/h7,9,11H,5-6,8,10,12-13H2,1-4H3,(H,18,19)​/b15-9+,16-11+
InChI Key GNWWFEVBHYESNK-XGGJEREUSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 124 Kb PDF

Download Safety Data Sheet (SDS) 33 Kb PDF

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Additional Information

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Inserts
QC Sheets
Certificates of Analysis
GCMS Data
References & Background Reading
Product Description References

1. Rando, R.R. Chemical biology of protein isoprenylation/methylation. Biochim Biophys Acta 1300 5-16 (1996).

2. Volker, C., Lane, P., Kwee, C., et al. A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues. FEBS Lett 295 189-194 (1991).

3. Pérez-Sala, D., Gilbert, B.A., Tan, E.W., et al. Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates. Biochem J 284 835-840 (1992).

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