N-acetyl-S-farnesyl-L-Cysteine • AFC (CAS 135304-07-3) (Inchi key XTURYZYJYQRJDO-JTCWOHKRSA-N) || Cayman Chemical | Supplier
N-acetyl-S-farnesyl-L-Cysteine
Item № 63270
CAS № 135304-07-3
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $25.00 $0.00
5 mg $63.00 $0.00
10 mg $113.00 $0.00
25 mg $250.00 $0.00

Pricing updated 2015-08-31. Prices are subject to change without notice.

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Description
Synonyms
  • AFC

N-acetyl-S-farnesyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).1,2 Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.

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Technical Information
Formal Name N-​acetyl-​S-​(3,​7,​11-​trimethyl-​2E,​6E,​10-​dodecatrienyl)-​L-​cysteine
CAS Number 135304-07-3
Synonyms
  • AFC
Molecular Formula C20H33NO3S
Formula Weight 367.5
Purity ≥98%
Formulation A solution in methyl acetate
SMILES CC(N([C@H]​(C(O)​=O)​CSC/C=C(CC/C=C(C)​/CC/C=C(C)​/C)​\C)​[H]​)​=O
InChI Code ​1S/C20H33NO3S/c1-15(2)​8-6-9-16(3)​10-7-11-17(4)​12-13-25-14-19(20(23)​24)​21-18(5)​22/h8,10,12,19H,6-7,9,11,13-14H2,1-5H3,(H,21,22)​(H,23,24)​/b16-10+,17-12+
InChI Key XTURYZYJYQRJDO-JTCWOHKRSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 87 Kb PDF

Download Safety Data Sheet (SDS) 31 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Volker, C., Lane, P., Kwee, C., et al. A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues. FEBS Lett 295 189-194 (1991).

2. Pérez-Sala, D., Gilbert, B.A., Tan, E.W., et al. Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates. Biochem J 284 835-840 (1992).

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