DEA NONOate

Cayman Chemical Item Number 82100

Diethylamine NONOate; DEA/NO (CAS 372965-00-9)

DEA NONOate (CAS 372965-00-9)

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Description

DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.1,2

1 Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ·NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. J Med Chem 34 3242-3247 (1991).

2 Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods Enzymol 268 281-293 (1996).

Synonyms
  • Diethylamine NONOate
  • DEA/NO
Formal Name Diethylammonium (Z)-​1-​(N,​N-​diethylamino)diazen-​1-​ium-​1,​2-​diolate
CAS Number 372965-00-9
Molecular Formula C4H11N3O2 · C4H11N
Formula Weight 206.3
Formulation A crystalline solid
Purity ≥98%
λmax 250 nm
ε 9
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCN(N([O-]​)​N=O)​CC.CC[NH2+]​CC
InCHI Code
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​1S/C4H10N3O2.C4H11N/c1-3-6(4-2)​7(9)​5-8;1-3-5-4-2/h3-4H2,1-2H3;5H,3-4H2,1-2H3/q-1;/p+1
InCHI Key
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YMXHDQWHPBQRQP-UHFFFAOYSA-O

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Size Price Quantity Subtotal
10 mg $19.00 $0.00
50 mg $52.00 $0.00
100 mg $95.00 $0.00
500 mg $428.00 $0.00
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Cart Total $0.00

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Pricing updated 2014-04-23. Prices are subject to change without notice.

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