8-hydroxy-2'-deoxy Guanosine

Cayman Chemical Item Number 89320

8-OH-dG (CAS 88847-89-6)

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8-hydroxy-2'-deoxy Guanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems.1,2,3,4

1. Floyd, R.A. Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 4 2587-2597 (1990).

2. Beckman, K.B., and Ames, B.N. Oxidative decay of DNA. J Biol Chem 272 19633-19636 (1997).

3. Spencer, J.P.E., Jenner, A., Chimel, K., et al. DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells. FEBS Lett 374 233-236 (1995).

4. Epe, B., Ballmaier, D., Roussyn, I., et al. DNA damage by peroxynitrite characterized with DNA repair enzymes. Nucleic Acids Res 24 4105-4110 (1996).

  • 8-OH-dG
Formal Name 2'-​deoxy-​8-​hydroxy-​guanosine
CAS Number 88847-89-6
Molecular Formula C10H13N5O5
Formula Weight 283.2
Formulation A crystalline solid
Purity ≥98%
λmax 206, 249, 296 nm
Stability 1 year
Storage Room temperature
Shipping Room temperature in continental US; may vary elsewhere
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8-hydroxy-2'-deoxy Guanosine is available in the following screening library:

Size Price Quantity Subtotal
1 mg $39.00 $0.00
5 mg $176.00 $0.00
10 mg $312.00 $0.00
25 mg $683.00 $0.00
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Cart Total $0.00

Pricing updated 2015-07-30. Prices are subject to change without notice.

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Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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Ann Arbor, Michigan 48108 USA


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