8-hydroxy-2'-deoxy Guanosine • 8-<wbr/>OH-<wbr/>dG (CAS 88847-89-6) (Inchi key HCAJQHYUCKICQH-VPENINKCSA-N) || Cayman Chemical | Supplier
8-hydroxy-2'-deoxy Guanosine
Item № 89320
CAS № 88847-89-6
Purity ≥98%
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $39.00 $0.00
5 mg $176.00 $0.00
10 mg $312.00 $0.00
25 mg $683.00 $0.00

Pricing updated 2015-08-29. Prices are subject to change without notice.

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Description
Synonyms
  • 8-OH-dG

8-hydroxy-2'-deoxy Guanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems.1,2,3,4

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Technical Information
Formal Name 2'-​deoxy-​8-​hydroxy-​guanosine
CAS Number 88847-89-6
Synonyms
  • 8-OH-dG
Molecular Formula C10H13N5O5
Formula Weight 283.2
Purity ≥98%
Formulation A crystalline solid
λmax 206, 249, 296 nm
SMILES NC(N1[H]​)​=NC(N([C@H]​2C[C@H]​(O)​[C@@H]​(CO)​O2)​C(N3)​=O)​=C3C1=O
InChI Code ​1S/C10H13N5O5/c11-9-13-7-6(8(18)​14-9)​12-10(19)​15(7)​5-1-3(17)​4(2-16)​20-5/h3-5,16-17H,1-2H2,(H,12,19)​(H3,11,13,14,18)​/t3-,4+,5+/m0/s1
InChI Key HCAJQHYUCKICQH-VPENINKCSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage Room temperature
Shipping Room temperature in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
Product Downloads

Download Product Insert 119 Kb PDF

Download Safety Data Sheet (SDS) 24 Kb PDF

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Additional Information

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Inserts
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GCMS Data
References & Background Reading
Product Description References

1. Floyd, R.A. Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 4 2587-2597 (1990).

2. Beckman, K.B., and Ames, B.N. Oxidative decay of DNA. J Biol Chem 272 19633-19636 (1997).

3. Spencer, J.P.E., Jenner, A., Chimel, K., et al. DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells. FEBS Lett 374 233-236 (1995).

4. Epe, B., Ballmaier, D., Roussyn, I., et al. DNA damage by peroxynitrite characterized with DNA repair enzymes. Nucleic Acids Res 24 4105-4110 (1996).

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