Prostaglandin E2-PEG11-biotin Exclusive

Cayman Chemical Item Number 9000376

PGE2-PEG11-biotin

Prostaglandin E2-PEG11-biotin

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Description

PGE2 is the major eicosanoid product of cyclooxygenase-1 and 2 in epithelial cells, leukocytes, reproductive tissues, and many others. PGE2 contracts smooth muscle, protects the gastric mucosa, modulates immune function, and regulates fertility and implantation. PGE2 acts through at least four G-protein coupled receptors, EP1 -EP4. PGE2-PEG11-biotin is an affinity probe which allows PGE2 to be detected or immobilized using the biotin ligand. The PEG11 moiety serves to separate the biotin linker from PGE2 with a hydrophilic spacer. It is thus a tool to be used in the elucidation of PGE2 actions or interactions in aqueous solutions.
Synonyms
  • PGE2-PEG11-biotin
Formal Name 11α,​15S-​dihydroxy-​9-​oxo-​prosta-​52,​13E-​dien-​1-​oyl-​polyethylene glycol 11-​N’-​biotinoyl-​1,​5-​diaminopentane
Molecular Formula C54H96N4O17S
Formula Weight 1105.4
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O=C1[C@H]​(C/C=C\CCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]​2SC[C@@]​(N3)​([H]​)​[C@]​2([H]​)​NC3=O)​=O)​=O)​[C@@H]​(/C=C/[C@@H]​(O)​CCCCC)​[C@H]​(O)​C1
InCHI Code
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​1S/C54H96N4O17S/c1-2-3-6-11-44(59)​16-17-46-45(48(60)​42-49(46)​61)​12-7-4-5-8-14-51(62)​55-18-20-65-22-24-67-26-28-69-30-32-71-34-36-73-38-40-75-41-39-74-37-35-72-33-31-70-29-27-68-25-23-66-21-19-56-52(63)​15-10-9-13-50-53-47(43-76-50)​57-54(64)​58-53
InCHI Key
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GJDVPBZZICGDDC-FLSODGMCSA-N

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Size Price Quantity Subtotal
50 µg $67.00 $0.00
100 µg $127.00 $0.00
250 µg $302.00 $0.00
500 µg $536.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2014-04-17. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

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