Progesterone 3-PEG11-biotin Exclusive

Cayman Chemical Item Number 9000645

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Description

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells.1 The main function of progesterone is to prepare the uterine lining for implantation of a fertilized ovum and to maintain pregnancy. Measurement of serum or plasma progesterone levels are used as an index to monitor ovulation and investigate luteal function. Progesterone 3-PEG11-biotin is an affinity probe that allows progesterone to be detected or immobilized using the biotin ligand. The PEG11 moiety serves to separate the biotin linker from progesterone with a hydrophilic spacer.

1. Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. 3rd ed. 973-1015 (1995).

Formal Name N-​(1-​(((E)-​(17-​acetyl-​10,​13-​dimethyl-​7,​8,​9,​11,​12,​13,​14,​15,​16,​17-​decahydro-​1H-​cyclopenta[a]phenanthren-​3(2H,​6H,​10H)-​ylidene)amino)oxy)-​2-​oxo-​6,​9,​12,​15,​18,​21,​24,​27,​30,​33,​36-​undecaoxa-​3-​azaoctatriacontan-​38-​yl)-​5-​((3aS,​6aR)-​2-​oxohexahydro-​1H-​thieno[3,​4-​d]imidazol-​4-​yl)pentanamide
Molecular Formula C57H97N5O16S
Formula Weight 1140.5
Formulation A solution in ethanol
Purity 98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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[H]​[C@]​12[C@]​(NC(N2)​=O)​([H]​)​CSC1CCCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CO/N=C3CCC(C(CCC4(C)​C5CCC4C(C)​=O)​C5CC6)​(C)​C6=C\3)​=O)​=O
InCHI Code
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​1S/C57H97N5O16S/c1-43(63)​47-10-11-48-46-9-8-44-40-45(12-14-56(44,2)​49(46)​13-15-57(47,48)​3)​62-78-41-53(65)​59-17-19-68-21-23-70-25-27-72-29-31-74-33-35-76-37-39-77-38-36-75-34-32-73-30-28-71-26-24-69-22-20-67-18-16-58-52(64)​7-5-4-6-51-54-50(42-79
InCHI Key
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HMXZDVJPIOMNQC-PHVMEARQSA-N

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Size Price Quantity Subtotal
500 µg $72.00 $0.00
1 mg $137.00 $0.00
5 mg $576.00 $0.00
10 mg $1,008.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2015-03-29. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

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