PtdIns-(1,2-dihexanoyl) (sodium salt)
Item № 9000660
Purity ≥98%
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100 µg $50.00 $0.00
500 µg $225.00 $0.00
1 mg $400.00 $0.00

Pricing updated 2016-02-05. Prices are subject to change without notice.

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The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-(1,2-dihexanoyl) is a synthetic analog of natural PtdIns featuring C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates IP3 and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

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Technical Information
Formal Name 1-(1,2-dihexanoylphosphatidyl)inositol, monosodium salt
Molecular Formula C21H38O13P • Na
Formula Weight 552.5
Purity ≥98%
Formulation A lyophilized powder
SMILES CCCCCC(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O)([O-])=O)OC(CCCCC)=O)=O.[Na+]
InChI Code 1S/C21H39O13P.Na/c1-3-5-7-9-14(22)31-11-13(33-15(23)10-8-6-4-2)12-32-35(29,30)34-21-19(27)17(25)16(24)18(26)20(21)28;/h13,16-21,24-28H,3-12H2,1-2H3,(H,29,30);/q;+1/p-1/t13-,16-,17-,18+,19-,20-,21-;/m1./s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 124 Kb PDF

Download Safety Data Sheet (SDS) 22 Kb PDF

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Additional Information

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References & Background Reading
Product Description References

1. Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).

2. Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

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