FABP4 (human recombinant) FITC conjugated

Cayman Chemical Item Number 9001068

A-FABP; Adipocyte FABP; ALBP; Fatty Acid Binding Protein 4; aP2

FABP4 (human recombinant) FITC conjugated

See more

Description

Source: recombinant N-terminal His-tagged protein expressed in E. coli · Mr: 19 kDa · FABP4 is one of nine known cytosolic fatty acid binding proteins ranging in size from 14-15 kDa containing 127-132 amino acids.1 Members of this protein family exhibit high-affinity for small lipophilic ligands and were named according to the tissue from which they were initially isolated.1 Studies suggest that FABPs are involved in the uptake and metabolism of fatty acids, in the maintenance of cellular membrane fatty acid levels, in intracellular trafficking of these substrates, in the modulation of specific enzymes of lipid metabolic pathways, and in the modulation of cell growth and differentiation.2 FABP family members have highly conserved three dimensional structures and 22-73% amino acid sequence similarity. FABP4 is composed of ten antiparallel β strands that form a barrel. FABP4 is a fat cell specific protein involved in facilitating the bidirectional flux of fatty acids into and out of the adipocyte in response to insulin and epinephrine.3,4,5

1 Zimmerman, A.W., and Veerkamp, J.H. New insights into the structure and function of fatty acid-binding proteins. Cell Mol Life Sci 59 1096-1116 (2002).

2 Massolini, G., and Calleri, E. Survey of binding properties of fatty acid-binding proteins chromatographic methods. J Chromatogr B 797 255-268 (2003).

3 Trillou, C.R., Arnone, M., Delgorge, C., et al. Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice. Am J Physiol Regul Integr Comp Physiol 284 R345-R353 (2003).

4 Hotamisligil, G.S., Johnson, R.S., Distel, R.J., et al. Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274 1377-1379 (1996).

5 Uysal, K.T., Scheja, L., Wiesbrock, S.M., et al. Improved glucose and lipid metabolism in genetically obese mice lacking aP2. Endocrinology 141(9) 3388-3396 (2000).

Synonyms
  • A-FABP
  • Adipocyte FABP
  • ALBP
  • Fatty Acid Binding Protein 4
  • aP2
Formal Name
Formulation 50 mM sodium phosphate, pH 7.2, containing 150 mM sodium chloride and 20% glycerol
Purity ≥95%
Stability 9 months
Storage -80°C
Shipping Wet ice in continental US; may vary elsewhere

Download free InCHI Key generation software

Size Price Quantity Subtotal
10 µg $175.00 $0.00
25 µg $416.00 $0.00
50 µg $788.00 $0.00
Bulk Contact
Cart Total $0.00

Please Login or Register to use this page.

Pricing updated 2014-04-24. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

FABP1 (rat recombinant)
FABP3 (human recombinant)
FABP4 (human recombinant)
FABP4 Inhibitor/Ligand Screening Assay Kit
FABP4 (mouse recombinant)
FABP4 Polyclonal Antibody
FABP5 (mouse recombinant)
Show all 7 Hide all but first 3

Downloads

Batch-specific Information

Get batch-specific data and documents by batch number


Separate multiple batch numbers with commas

Cayman Chemical Company regularly evaluates our shipping methods to ensure product stability is maintained and our corporate environmental impact is minimized. Products selected for review are evaluated and shipping methods are certified by our Scientists. While occasionally our method of shipping a product may change, rest assured the shipping conditions on all Cayman Chemical products have been reviewed and validated.

Upon receipt, it is important to check the storage requirements of your products and place them at the appropriate temperature. Products shipped without ice may require frozen storage for long term stability.

Cayman Chemical was formed over thirty years ago by demonstrating the value of naturally growing gorgonian corals as a renewable, economically viable source of prostaglandins. Today we operate our business knowing that we owe our start to the renewable resources our environment had provided. As Cayman Chemical continues to grow we consistently evaluate our business processes to ensure we are operating at the highest environmental standards.

See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · Experimental Biology 2014 · San Diego, California · April 26-30, 2014 · Booth 323 Join us! · ASPET Symposium 2014: Scientists versus Street Chemists: The Toxicity of Designer Marijuana · San Diego, California · April 30, 2014
Other Resources
About Cayman Management Team Company Profile ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map Conference Travel Grants

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2014 Cayman Chemical Company

Manufacturer, supplier, and vendor of biochemical reagents, assay kits, forensic chemistry standards, antibodies, and proteins for scientific research · Buy now! · Analytical testing services and custom synthesis also available

Lost password?