9,12-Octadecadiynoic Acid
Item № 90400
CAS № 2012-14-8
Purity ≥98%
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1 mg $61.00 $0.00
5 mg $275.00 $0.00
10 mg $488.00 $0.00

Pricing updated 2015-09-04. Prices are subject to change without notice.

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Description
Synonyms
  • Ro 3-1314

Ro 3-1314 is an inhibitor of both COX and lipoxygenase.1,2 Ro 3-1314 inhibits ram seminal vesicle COX with a Ki of 0.6 µM.1 It is a more effective inhibitor of COX-1 than of 15-LO, inhibiting 95% and 68%, respectively, of these enzymatic activities when used at a concentration of 48 µM.2

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Technical Information
Formal Name 9,​12-​octadecadiynoic acid
CAS Number 2012-14-8
Synonyms
  • Ro 3-1314
Molecular Formula C18H28O2
Formula Weight 276.4
Purity ≥98%
Formulation A crystalline solid
SMILES CCCCCCCCCCCCCCCCCC(=O)​O
InChI Code ​1S/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)​20/h2-5,8,11-17H2,1H3,(H,19,20)​
InChI Key KDYILQLPKVZDGB-UHFFFAOYSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year
Product Downloads & Resources
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Download Product Insert 113 Kb PDF

Download Safety Data Sheet (SDS) 22 Kb PDF

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Additional Information

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Inserts
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References & Background Reading
Product Description References

1. Vanderhoek, J.Y., and Lands, W.E.M. Acetylenic inhibitors of sheep vesicular gland oxygenase. Biochim Biophys Acta 296 374-381 (1973).

2. Downing, D.T., Barve, J.A., Gunstone, F.D., et al. Structural requirements of acetylenic fatty acids for inhibition of soybean lipoxygenase and prostaglandin synthase. Biochim Biophys Acta 280 343-347 (1972).

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