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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
13100 13,14-dihydro-15-keto-tetranor Prostaglandin D2 Exclusive 1204116-69-7 ≥95% 2009-10-28 13.389705340699 13-14-dihydro-15-keto-tetranor-prostaglandin-d2 PGDM metabolites PGD2 CRTH2 DP2 tetranors agonists prostaglandins receptors CRTH2/DP2 13.389705340699
13812 17β-hydroxy Wortmannin Exclusive 58053-83-1 ≥98% 2010-05-18 14.079069981584 17-hydroxy-wortmannin phosphoinositide 3-kinase PI3K mTOR inhibitors inhibits inhibition inhibitory cancers 17-hydroxywortmannins 17-hydroxy wortmannins hydroxywortmannins PI3-K HWT phosphatidylinositol 14.079069981584
10010188 1-Hexadecyl Lysophosphatidic Acid 52603-03-9 ≥98% 2007-11-10 20.290165745856 1-hexadecyl-lysophosphatidic-acid Alkyl glycero phosphate 16:0; 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate; AGP 16:0 LPAs G-proteins Gproteins GPCRs cell proliferation smooth muscles contractions platelet aggregation neurite retraction 20.290165745856
10010292 1-Hexadecyl Lysophosphatidic Acid (sodium salt) - ≥98% 2007-11-10 18.804254143646 1-hexadecyl-lysophosphatidic-acid-sodium-salt Alkyl glycero phosphate 16:0 (sodium salt); 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt); AGP 16:0 (sodium salt) LPAs G-protein Gprotein GPCRs cell proliferations smooth muscles contractions platelet aggregation neurite retraction 52603-03-9 18.804254143646
10954 1-NA-PP1 221243-82-9 ≥98% 2011-09-30 49.868011049724 1-na-pp1 1-Naphthyl-PP1; PP1 Analog inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn Cdk2 c-Abl cAbl mammalian yeast 1NMPP1 1NA-PP1 cells permeable tyrosine cell-permeable AS Src-family Src I338G v-Src-AS1 49.868011049724
13330 1-NM-PP1 221244-14-0 ≥95% 2009-07-22 44.961077348066 1-nm-pp1 PP1 Analog II inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn Cdk2 CAMKII mammalian yeast 1NMPP1 44.961077348066
10007072 1-Palmitoyl-2-linoleoyl PE 26662-95-3 ≥98% 2005-12-20 13.717070799184 1-palmitoyl-2-linoleoyl-pe (1-palmitoyl, 2-linoleoyl)-Phosphatidylethanolamine; PLPE; (1-palmitoyl, 2-linoleoyl)-Phosphoethanolamine phosphoethanolamines phosphatidylethanolamines lipids biosynthesis lysophospholipases anandamides biochemical pathways fatty acids cellular membranes A2 D substrates sPLA2-IIA 13.717070799184
11046 2-NBDG 186689-07-6 ≥98% (mixture of α and β) 2012-09-06 100.831887661142 2-nbdg NBD-Glucose fluorescence fluorescent probes glucose uptake cells viability contrast reagents neoplasia cancers diabetes flow cytometry microscopy 213484-93-6 100.831887661142
10005707 (2S)-OMPT 1217471-69-6 ≥98% 2005-10-19 17.812836095764 -2s-ompt GPR lysophosphatidic acids lipids mediators receptors LPA1/Edg-2 LPA2/Edg-4 LPA3/Edg-7 LPA4/GPR23 agonists calcium mobilization Sf9 cells (2R)-OMPT release assays LPA3-transfected rat hepatoma Rh7777 17.812836095764
10727 3,5-dimethyl PIT-1 701947-53-7 ≥98% 2011-05-25 7.477375690607 3-5-dimethyl-pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domain cancers inhibitors Akts PDK1 PTENs proteins binding inhibits inhibited inhibition DM-PIT-1 7.477375690607
13221 3-hexanoyl-NBD Cholesterol 201731-19-3 ≥98% 2009-06-05 2.409506774532 3-hexanoyl-nbd-cholesterol 3-C6-NBD Cholesterol fluorescent cholesterol NBD fluorophore membrane lipids flourescently-tagged probes 2.409506774532
10009804 3-PT-PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) - ≥98% 2009-03-20 9.090662983425 3-pt-ptdins-3-4-5-p3-1-2-dioctanoyl-sodium-salt 3-Phosphorothioate-Phosphatidylinositol-4,5-diphosphate C-8 3-PT-PtdIns(3,4,5)-P3 PtdIns(3,4,5)-P3 PTEN PIP PIP(3,4,5) cells signaling PI3 kinases cancers phosphatidyl inositols phosphates membrane phospholipids signalling sodium transport 922712-46-7 9.090662983425
15580 5-Bromo-2'-deoxyuridine New 59-14-3 ≥98% 2014-03-03 0E-12 5-bromo-2-deoxyuridine Broxuridine; BrdU; Bromodeoxyuridine; NSC 38297 723-​73-​9 3445-​26-​9 1236362-​78-​9 5-BrdU bromodeoxyuridine cells proliferation proliferates thymidine analogs DNA S phases cycles labels BrdU bromo deoxyuridine biology dyes stains indicators molecular 2'-Deoxy-5-bromouridine 5-BDU 5-Bromo-2'-desoxyuridine 5-Bromodeoxyuridine 5-Bromodesoxyuridine 5-Bromouracil deoxyriboside 5-Bromouracil-2-deoxyriboside BDU BRUDR BUdR BrdUrd 0E-12
10009315 6-Aminonicotinamide 329-89-5 ≥98% 2008-11-21 5.682320441989 6-aminonicotinamide SR 4388; NSC 21206; 6-AN inhibitors inhibits inhibition 6-phosphoguconate dehydrogenase cancers ATPs oxidative injury neurodegeneration cardiovascular 5.682320441989
10009856 7-AAD Cell Viability Assay Kit - 2008-10-29 55.762720823954 7-aad-cell-viability-assay-kit 7-Amino Actinomycin D Cell Viability Kit kits 7AAD measurement cells fixation blocking cytoxicity effects environmental toxins drug fluorescence fluorescent cell-based assays cell based assay cba 55.762720823954
14431 8-bromo-Cyclic AMP (sodium salt) 76939-46-3 ≥98% 2013-05-21 9.950155514630 8-bromo-cyclic-amp-sodium-salt 8-bromo-cAMP (sodium salt) 23583-48-4 cyclic-AMP-dependent proteins kinases PKAs activators signals transductions cAMPs analogs cells sodium salts cAMP permeable activates activations GMP reduced potency hydrolysis membranes permeability cells Na+ cAMP-dependent cGMP-dependent dependents 9.950155514630
12011 8-CPT-Cyclic AMP (sodium salt) 93882-12-3 ≥98% 2013-05-21 7.386803765090 8-cpt-cyclic-amp-sodium-salt 8-(p-Chlorophenylthio)-cAMP; 8-CPT-cAMP 41941-66-6 cyclic-AMP-dependent kinases cyclic-GMP-dependent proteins PKAs PKGs inhibitors activators phosphodiesterases PDE VA cGMP PDE III cAMP PDE IV signals signaling transductions PDEs cyclics AMPs cAMP cGMP lipophilic acitvators cells permeables analogs CPT GMP pathways sodium salts Na+ inhibits inhibitors cAMP-dependent dependents cGMP-dependent cAMP-specific cGMP-specific cAMP-inhibited cGMP-inhibited inhibited specific 7.386803765090
11016 A-23187 52665-69-7 ≥98% 2011-10-25 12.024072612470 a-23187 Calcimycin calcium cells activations ionophore signaling apoptosis antibiotic A23187 A 23187 37259-87-6 37263-57-3 51257-80-8 51310-65-7 53095-21-9 12.024072612470
13653 ABT-869 796967-16-3 ≥98% 2010-12-09 5.756795580110 abt-869 Linifanib inhibitors RTK tyrosine kinases VEGF PDGF cancers KDR Flt1 Flt3 Flt4 CSF-1R KIT acute myeloid leukemia antiproliferative anti-proliferative ABT 869 ABT869 Indazoles 5.756795580110
14465 Ac-DEVD-CMK 285570-60-7 ≥98% 2013-05-13 4.351522406384 ac-devd-cmk Caspase-3 Inhibitor III; Ac-Asp-Glu-Val-Asp-CMK inhibitors caspase-3 apoptosis Ac-DEVD-CMK caspase-6 caspase-7 caspase-8 caspase-10 inhibits inhibitions caspases 3 6 7 8 10 III cells permeables cell-permeable irreversible AcDEVDCMK Ac DEVD CMK deaths 4.351522406384
11421 Actinomycin D 50-76-0 ≥98% 2012-10-03 6.007734806630 actinomycin-d Cosmegen; Dactinomycin; NCI C04682; Oncostatin K; Meractinomycin; NSC 3053 1402-51-3 1402-58-0 C1 AIV I1 IV X1 A IV 7 AD actinomycindioic D acid dilactone chounghwamycin B dactinomycin D lyovac NCIC04682 NCI-C04682 NSC3053 NSC-3053 antibiotics DNAs transcriptions RNAs synthesis anticancers cells deaths antitumors anti-cancers anti cancers anti-tumors anti tumors agents fluorescent derivative 7-aminoactinomycin 7-AAD AAD 7AAD markers actinomycin-d 6.007734806630
14498 Adenosine 5'-triphosphate (sodium salt) 987-65-5 ≥95% 2013-05-23 2.399779983376 adenosine-5-triphosphate-sodium-salt NSC 20268; ATP 56-65-5 56560-86-2 1181748-98-0 signals transductions enzymes substrates cells biology energy storage metabolisms coenzymes signals signaling adenylates cyclases cAMPs second messengers 2 2nd energies stores stored ATPs adenosines 5 triphosphates in vivo metabolic pumps co-enzyme co enzymes enzymatic reactions rxns cellular processes respirations biosynthetic motility divisions adetphos disodium sodium 2Na+ Na2+ salts NSCs 20268 NSC20268 NSC-20268 2.399779983376
14957 Adenosine 5'-(γ-thio)-triphosphate (lithium salt) 93839-89-5 ≥90% 2013-10-03 2.399779983376 adenosine-5-thio-triphosphate-lithium-salt ATPγS 35094-46-3 purinergic receptors ATP P2Y2 receptors P2Y11 P2Y substrates analogs agonists ATPγS adenosines thriphosphates lithium salts analogs ATP DNA kinases substrates RNA eIF4A eukaryotic initiations factors non-hydrolyzable G-protein-coupled G proteins coupled N-acetylglucosamines RNA-stimulated nucleotides hydrolysis RNA stimulated 2.399779983376
13297 AG-126 118409-62-4 ≥95% 2009-07-14 5.860624448008 ag-126 Tyrphostin AG-126 tyrphostins proteins tyrosine inhibitors inhibits inhibition cells growth epidermal growth factors receptors kinase GFRK EGFs EGFRK PDGF PDGFRK platelet-derived platelet derived phosphorylation ERK1 p44 ERK2 p42 TNF-α TNFα TNF α NF-κB NFκB NF κB COX-2 COX2 iNOS inflammation 5.860624448008
10010568 AG-370 134036-53-6 >95% (cis/trans mixture) 2009-01-09 1.380481482801 ag-370 NSC 651712 PTK inhibitor tyrphostin tyrosine PDGF receptor kinase EGF receptor antiproliferative 1.380481482801
10793 AG-879 148741-30-4 ≥95% 2011-05-06 4.864360125942 ag-879 Tyrphostin AG-879 PTKs inhibitors tyrphostins tyrosine kinases antiproliferative NGF TrkA ErbB2 FLK-1 AG879 AG 879 inhibited inhibition 4.864360125942
13733 Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282) - 2010-01-11 1.119605367008 akt1-phospho-ser473-monoclonal-antibody-clone-104a282 antibodies Akts PKBs peptides Akt-1 Akt 1 protein kinase B serine threonine western blots blotting immunoblotting WB IP Immunoprecipitation IP 1.119605367008
13732 Akt1 Polyclonal Antibody - 2010-01-11 1.119605367008 akt1-polyclonal-antibody antibodies Akts PKBs peptides Akt-1 Akt 1 protein kinase B serine threonine western blots blotting immunoblotting WB 1.119605367008
14794 ALK5 Inhibitor II 446859-33-2 ≥98% 2013-08-09 35.582039265983 alk5-inhibitor-ii E 616452; SJN 2511; RepSox TGF-β1 receptors serine/threonine kinases ALK5 inhibitors E 616452 RepSox SJN 2511 stem cells pluripotency reprogramming Sox2 Nanog TGFs ser/thr serines threonine ALK-5 ALKs 5 five inhibits inhibitions E-616452 S616452 SJN-2511 SJN2511 Rep Sox Rep-Sox Soxs 2 two Sox-2 biology intracellular signaling stem research biochemistry permeable selective autophosphorylation HepG2 p38 MAPK GSK3 transcription factors pathways 35.582039265983
15526 ALK5 Inhibitor II (hydrochloride) New - ≥98% 2014-02-21 195.312316968131 alk5-inhibitor-ii-hydrochloride SJN 2511; E 616452; RepSox 446859-33-2 1450722-69-6TGF-β1 receptors serine/threonine kinases ALK5 inhibitors E 616452 RepSox SJN 2511 stem cells pluripotency reprogramming Sox2 Nanog TGFs ser/thr serines threonine ALK-5 ALKs 5 five inhibits inhibitions E-616452 S616452 SJN-2511 SJN2511 Rep Sox Rep-Sox Soxs 2 two Sox-2 biology intracellular signaling research biochemistry permeable selective autophosphorylation HepG2 p38 MAPK GSK3 transcription factors pathways TGF-β1 HCl Nanog reprogramming 195.312316968131
11679 Andrographolide 5508-58-7 ≥98% 2012-06-25 4.567204419889 andrographolide andrographis andrographolid 5953-53-7 101060-34-8 diterpenoids medicinal plants immunosuppression antithrombosis anti-inflammatory anti-inflammatory anti inflammatory antineoplastic anti-neoplastic neoplastic anti-viral antiviral viral anti-bacterial antibacterial bacterial anti-diabetic antidiabetic diabetics anti-oxidative stress antioxidative oxiddative antipyretic anti-pyretic pyretic anti-oedematogenic antioedematogenic oedematogenic anti-nociceptive antinociceptive nociceptive nuclear factor kappa B NF-κB p50 CYP1A endothelial cells E-selectin neutrophils allergic inflammations asthma CYP450 eselectin E selectin signaling signalling Andrographis paniculata inhibits inhibition inhibitors NFκB NF κB DNA 4.567204419889
600300 Annexin V FITC Assay Kit - 2010-05-11 56.893373793180 annexin-v-fitc-assay-kit assays kits measures measurements apoptosis cells death cycles tissues homeostasis dysregulation neurodegenerative diseases ischemic damages autoimmune disorders cancers drugs discovery signaling pathways membranes phospholipids phosphatidylserines phosphatidylethanolamines leaflets bilayers externalizations residues plasma phospholipids binding proteins fluorochrome-labeled fluorochromes fluorescence microscopy flow cytometry FC plate readers TUNEL TdT-mediated dUTP Nick-End Labeling analysis ISEL in situ end labeling DNA laddering detection fragmentation FITC-conjugated fluoresceins 56.893373793180
10575 Apicidin 183506-66-3 ≥98% 2012-01-27 9.137217478654 apicidin OSI 2040 funfal toxins malaria HDAC HAT histones deacetylase transcriptions epigenetics anticancer anti-cancer antiproliferation antiparasitic anti-proliferation anti-parasitic apicomplexan parasites HDAC3 HDAC-3 NcoR HDAC3/NcoR class I HDACs p21 WAF1/Cip1 WAF1 Cip1 gelsolin cells cycle morphology inhibits inhibitors inhibitions chromatin cancers deacetylase modification 9.137217478654
13495 ARAP2 Polyclonal Antibody - 2009-09-03 0.298385040374 arap2-polyclonal-antibody Centaurin-δ-1 antibodies proteins A chromatography WB western blots immunoblotting IHC immunohistochemistry blotting 0.298385040374
13496 AROS Polyclonal Antibody (aa 1-50) - 2009-09-03 0E-12 aros-polyclonal-antibody-aa-1-50 WB western blots immunoblotting protein nucleolar RPS19 cDNA chromosome 22q13.1 antibodies blotting 0E-12
13498 ARRB2 Polyclonal Antibody - 2009-09-22 5.424295580110 arrb2-polyclonal-antibody β-Arrestin-2 WB IHC western blots blotting immunoblotting antibodies immunohistochemisty ARRB-2 βarrestin2 β-arrestin2 β arrestin 2 β2R receptors adrenergic 5.424295580110
11226 AS-703026 1236699-92-5 ≥98% 2012-03-08 12.817928176795 as-703026 MSC1936369B AS 703026 AS703026 1204531-26-9 MEKs MEK1/2 MEK-1/2 MEK1 MEK2 ERKs Ras Raf inhibitors inhibits inhibitions cancers multiple myeloma EGFR signals transductions kinases cells biology 12.817928176795
600140 Autophagy/Cytotoxicity Dual Staining Kit - 2009-07-14 57.284581689029 autophagy-cytotoxicity-dual-staining-kit assays kits measuring measurement MDC cell-based autophagy cells cytotoxicity staining autofluorescent autofluorescence substances multilamellar body bodies ions trapping mechanisms membranes lipids probes autophagic vacuoles cultured degradation digestion intracellular lysosomes organelles misfolded proteins microorganisms cytoplasms double membranes autophagosomes autolysosomes homeostasis dysregulation cancers infections aging degenerative diseases stress death apoptosis 57.284581689029
10803 Autotaxin (human recombinant) - ≥95% 2011-04-04 15.703784530386 autotaxin-human-recombinant ENPP-2; Lysophospholipase D; Ectonucleotide Pyrophosphatase/Phosphodiesterase-2 lipids hydrolysis lysophophatidyl choline lysophophatidic acids secreated glycosylated active 15.703784530386
10008612 azido-FTY720 881914-35-8 ≥98% 2006-09-13 50.415260896255 azido-fty720 sphingosine 1 phosphate S1P1 S1P3 S1P4 S1P5 immunosuppressant kinases photoreactive agonists analogs allograft transplants inhibits inhibitors inhibition lymphocytes emigration lymphoid organs in vivo Azido FTY720 FTY 720 50.415260896255
11706 BAPTA 85233-19-8 ≥95% 2013-10-03 10.274059551166 bapta calciums chelators ions Ca2+ concentrations indicators dyes membranes permeable membrane-permeable binds binders bindings carboxylic acids measurements manipulation free cells biology stains BAPTA functional groups 4 four two 2 derivatives extracellular 10.274059551166
15551 BAPTA-Acetoxymethyl ester New 126150-97-8 ≥98% 2014-02-07 0E-12 bapta-acetoxymethyl-ester BAPTA-AM dyes stains indicators cells biology ions channels blockers blocks blocking cell-permeable calcium AMs acetoxymethyl esters analogs binds cytoplasmic esterases signaling inhibits inhibitions inhibition voltage-gated coltage gated potassium Kv chelators 0E-12
10011131 BAY-41-8543 Exclusive 256498-66-5 ≥98% 2009-11-16 11.320285451197 bay-41-8543 soluble guanylate cyclase sGC nitric oxide NO GTP cyclic GMP cGMP agonist stimulator platelet aggregation blood pressure bleeding time thrombosis pulmonary hypertension BAY 41-8543 BAY 41 8543 11.320285451197
15922 BCECF-Acetoxymethyl ester New 117464-70-7 ≥95% 2014-04-15 0E-12 bcecf-acetoxymethyl-ester BCECF-AM 133561-​37-​2 133561-​38-​3 134331-​92-​3 1189115-​29-​4 1119449-23-8 928715-17-7 fluorescence fluorescent probes dyes stains indicators cells biology intracellular AMs BCECF-AM BCECFAM BCECF membranes permeant esterases polar fluorescein derivatives flow cytometry FC spectrofluorometry ions potassium pH membrane-permeant ratios imaging 0E-12
11426 Beauvericin 26048-05-5 ≥98% 2012-02-22 11.397799263351 beauvericin toxins mycotoxins fungus insects apoptosis Beauveria bassiana B. bassiana fungal parasites arthropods fusarium pathogens cells SF-9 NSC708472 NSC-708472 NSC 708472 11.397799263351
13298 Bisindolylmaleimide I 133052-90-1 ≥95% 2009-08-28 28.117635780766 bisindolylmaleimide-i BIM I; GF 109203X; Gö 6850 634199-82-9 682340-45-0 inhibitors inhibits inhibitions PCK GSK-3 GSK3 staurosporine 5-HT3 receptors 5HT3 Go 6850 28.117635780766
11020 Bisindolylmaleimide II 137592-45-1 ≥97% (isomer mixture) 2012-03-13 16.301343516381 bisindolylmaleimide-ii BIM II PKC staurosporines inhibitors inhibits inhibition PDK1 PKA kinases C PKCα signaling insulin ligands binding protein kinase C 16.301343516381
11072 Bisindolylmaleimide III 137592-43-9 ≥98% 2013-01-28 25.369948013300 bisindolylmaleimide-iii BIM III PKC staurosporine inhibitors PDK1 S6K1 MAPKAP-K1 RSK2 MSK1 kinases bisindolymaleimide III 3 proteins inhibitors inhibits staurosporine S6K1 MAPKAP-K1 MAPKAPK1 MAPKAP K1 RSK2 MSK1 potency signaling, pathways 25.369948013300
13334 Bisindolylmaleimide IX (mesylate) 138489-18-6 >98% 2009-10-28 16.499254143646 bisindolylmaleimide-ix-mesylate Ro 31-8220; BIM IX bisindolylmaleimide inhibitor protein kinase C PKC PKC-α PKC-βI PKC-βII PKC-γ PKC-ε PKA CaM kinase II glycogen synthase kinase-3 GSK-3 Ro318220 GSK3 125314-64-9 Ro-31-8220 75-75-2 16.499254143646
11073 Bisindolylmaleimide XI (hydrochloride) 145333-02-4 ≥98% 2012-03-21 16.004115115240 bisindolylmaleimide-xi-hydrochloride Ro 31-0432; BIM XI 131848-98-1 Ro32-0432 Ro-32-0432 Ro-320432 Ro 320432 Ro320432 PKC isozymes Staurosporine inhibitors inhibits inhibition proteins kinases C PKCα PKCβI PKCε hydrochloride HCl cells hearts T-cell T cell inflammatory inflammation Ro 32-0432 16.004115115240
13124 BIX01294 (hydrochloride hydrate) - ≥98% 2009-12-03 29.266186063090 bix01294-hydrochloride-hydrate euchromatin genes expressions epigenetics G9a histones methyltransferase HMTase embryogenesis imprinting lymphocytes development inhibitors proteins GLP stem cells 935693-62-2 29.266186063090
13013 (−)-Blebbistatin 856925-71-8 ≥98% 2009-04-16 130.436677298021 -blebbistatin (S)-Blebbistatin inhibitors muscles myosin ATPase smooth muscle bleb apoptosis cell migration chemotaxis cytokinesis cells division growth UV light blebs (-)-(S)-Blebbistatin 130.436677298021
13165 (+)-Blebbistatin 1177356-70-5 ≥98% 2009-04-16 64.772988072494 -blebbistatin (R)-Blebbistatin inhibitors muscles myosin ATPase smooth muscle bleb apoptosis cell migration chemotaxis cytokinesis cells division growth UV light (+)-(R)-Blebbistatin inhibition inhibited 64.772988072494
13186 (±)-Blebbistatin 674289-55-5 ≥98% 2009-06-09 110.648695547409 -blebbistatin inhibitors muscles myosin ATPase smooth bleb apoptosis cells migration chemotaxis cytokinesis division growth UV lights 110.648695547409
11069 BRD2 bromodomains 1 and 2 (human recombinant) - ≥90% 2011-12-20 6.453718427548 brd2-bromodomains-1-and-2-human-recombinant RING3; RNF3; Bromodomain containing protein 2 BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysines regulations trandcription proteins domains nucleosomes BRDT BRD-T cells inflammatory inflammation mitosis viruses viral hosts binding binds molecules inhibitors inhibits inhibition humans diseases 6.453718427548
14822 BRD4 bromodomains 1 and 2 (human recombinant; aa 2-477) - ≥70% 2013-08-09 0.410534445822 brd4-bromodomains-1-and-2-human-recombinant-aa-2-477 MCAP; Bromodomain containing protein 4; HUNK1 BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRDs BRD-2 BRD-3 BRD-4 bromodomains epigenetics extra terminals BRDs 2 3 4 two three four transcription 0.410534445822
11052 BRD4 bromodomains 1 and 2 (human recombinant; aa 49-460) - ≥90% 2011-12-20 6.375789200382 brd4-bromodomains-1-and-2-human-recombinant-aa-49-460 Bromodomain containing protein 4; MCAP; HUNK1 BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysines regulations trandcription proteins domains nucleosomes BRDT BRD-T cells inflammatory inflammation mitosis viruses viral hosts binding binds molecules inhibitors inhibits inhibition humans diseases 6.375789200382
13497 BRD4/HUNK1 Polyclonal Antibody - 2009-09-22 0.677700807479 brd4-hunk1-polyclonal-antibody Bromodomain containing protein 4 BET antibodies WB western blots blotting immunoblotting terminus isoforms 0.677700807479
11861 Brefeldin A 20350-15-6 ≥98% 2012-07-11 7.673342541437 brefeldin-a NSC 56310; Nectrolide; BFA; Synergisidin; Ascotoxin; Cyanein; Decumbin; NSC 89671; NSC 244390; NSC 107456 3459-16-3 11006-23-8 11039-44-4 19022-59-4 27740-36-9 31874-13-2 60132-23-2 78206-62-9 cyanaein NSC107456 NSC-107456 NSC244390 NSC-244390 NSC56310 NSC-56310 NSC89671 NSC-89671 natural products endosomes GEFs Arf endocytosis inhibitors golgi complex golgi apparatus endoplasmic reticulum secretion proteins trafficking vesicles inhibits inhibition fungal metabolites intracellular transport Sec7 Sec-7 Sec 7 domains guanine exchange factors ADP cells plants fungi invertebrates vertebrates brefeldin-A 7.673342541437
14932 BX-795 New 702675-74-9 ≥98% 2013-10-28 19.370070793480 bx-795 BX795 BX-795 inhibitors kinases proteins signals transduction inflammation cells cycles BXs BX795 795 potent ATP inhibits inhibitions 3-phosphoinositide-dependent 1 phosphoinositide dependent extracellular signal-regulated signals regulated 8 ERK-8 ERKs 8 eight ERK8 MAPK-interacting 2 two MAPKs interacting MNK2 MNKs MNK-2 auroras B C aurora-B aurora-C MAP/mictrotubule MAP microtubule affinity-regulating affinity regulating TNF associated factors NK-kB activator TBK-1 TBK1 TBKs IKKs competetive PDK1 19.370070793480
10681 C-16 Ceramide 24696-26-2 ≥98% 2011-03-08 4.673446132596 c-16-ceramide Palmitoyl Ceramide sphingomyelins apoptosis ceramides lipids membranes second messengers C16 ceramides longevity assurance homologs 6/LASS6 Ceramides C 16 4.673446132596
10724 C-20 Ceramide 7344-02-7 ≥98% 2011-03-08 2.497064917126 c-20-ceramide sphingomyelins apoptosis differentiation brains C20-ceramide C20:0 ceramides 20:0 synthesis 1 2 synthases 2.497064917126
700550 Calcium Assay Kit - 2011-05-12 114.371212400245 calcium-assay-kit kits assays measures measurements Ca Ca2+ minerals skin cells hair nails urination sweat feces skeletal systems tissues bones teeth mass neurological endocrine cardiovascular digestive metabolic pulmonary heart cancers diseases homogenates lysates o-Cresolphthalein-calcium 114.371212400245
12076 Canertinib (hydrochloride) 289499-45-2 ≥98% 2012-11-06 6.230800411889 canertinib-hydrochloride PD 183805; CI 1033 267243-28-7 338796-35-3 HCl dihydrochloride hydrochloride CI1033 CI-1033 PD183805 PD-183805 receptors tyrosine kinases EGFR HER-2 HER-3 HER-4 proliferation tumors inhibitors, anti-cancers inhibits inhibitions anticancer pan-ErbB ErbB quinazoline HERs HER2 HER3 HER4 proliferation malignant peripheral nerves sheath cells neuroblastoma acute myeloid leukemia T98G HCT8 breasts resistance proteins BCRP 6.230800411889
13916 Caspase-14 Monoclonal Antibody (Clone 70A1426) - 2010-09-13 1.582549936251 caspase-14-monoclonal-antibody-clone-70a1426 caspases cysteine proteases mediators programmed cells death apoptosis prodomain catalytic subunits pentapeptides QACRG embryonic tissues ontogenesis western blots immunoblotting blotting WB FC flow cytometry antibodies 14 fourteen 1.582549936251
14464 Caspase-3/7 Inhibitor I 1110670-49-9 ≥98% 2013-05-13 2.837049723757 caspase-3-7-inhibitor-i inhibitors caspase-3 caspase-7 caspases 3 7 inhibits inhibitions potent reversible isatins sulfonamide-based sulfonamides 9 1 2 4 6 8 apoptosis camptothecin-treated camptothecin treated treats Jurkat cells condrocytes hydrophobic residues S2 catalytic cysteines I 2.837049723757
10009135 Caspase-3 Fluorescence Assay Kit - 2007-08-06 33.111463185642 caspase-3-fluorescence-assay-kit assays kits caspases fluorescent cells death apoptosis necrosis aspartate-specific cysteinyl fluorescence fluorometric proteases family mitochondrial mitochondria electrons transport oxidative phosphorylation adenosine triphosphate ATP cytochromes C caspase-9 anti-cancers drugs N-Ac-DEVD-N'-MC-R110 HTS high throughput screening N-Ac-Asp-Glu-Val-Asp-CHO cell-based assay cell based assay cba 33.111463185642
13912 Caspase-7 Monoclonal Antibody (Clone 25B881.1) - 2010-09-09 1.409454013649 caspase-7-monoclonal-antibody-clone-25b881-1 caspases seven caspase 7 cysteine proteases programmed cell death apoptosis catalytic subunits MCH3 MCH-3 MCH p20 p12 caspase-3 western blots immunlotting blotting WB immunohistochemistry IHC 1.409454013649
13914 Caspase-8 Monoclonal Antibody - biotin (Clone 90A992) - 2010-09-09 0.252104470115 caspase-8-monoclonal-antibody-biotin-clone-90a992 caspases eight 8 cysteine proteases key mediators programmed cells death apoptosis FLICE ICE CD95 CD-95 CDs 95 subunits a2be active enzyme inhibitors inhibits inhibition ELISA biotinylated biotins 0.252104470115
13913 Caspase-8 Monoclonal Antibody (Clone 90A992) - 2010-09-09 1.409454013649 caspase-8-monoclonal-antibody-clone-90a992 caspases eight 8 cysteine proteases key mediators programmed cells death apoptosis FLICE ICE CD95 CD-95 CDs 95 subunits a2be active enzyme inhibitors inhibits inhibition antibodies western blots blotting immunoblotting WB immunohistochemistry IHC flow cytometry FC 1.409454013649
13702 Cav1.2 Calcium Channel Monoclonal Antibody (Clone S57-46) - 2009-11-05 1.823204419890 cav1-2-calcium-channel-monoclonal-antibody-clone-s57-46 antibodies western blotting blots immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC channels ions fusion proteins gated voltage-gated ligand-gated voltage ligand 1.823204419890
13703 Cav1.3 Calcium Channel Monoclonal Antibody (Clone S38-8) - 2009-11-05 0.607734806630 cav1-3-calcium-channel-monoclonal-antibody-clone-s38-8 antibodies channels ions fusion proteins CACNAID western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC gated voltage-gated ligand-gated voltage ligand 0.607734806630
13706 Cav1.3 Calcium Channel Monoclonal Antibody (Clone S48A-9) - 2009-11-12 1.823204419890 cav1-3-calcium-channel-monoclonal-antibody-clone-s48a-9 antibodies channels ions fusion proteins CACNAID western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC gated voltage-gated ligand-gated voltage ligand 1.823204419890
13700 Cavβ1 Calcium Channel Monoclonal Antibody (Clone S7-18) - 2009-10-24 0.607734806630 cav-1-calcium-channel-monoclonal-antibody-clone-s7-18 antibodies western blotting immunoblotting WB IHC ICC IF immunohistochemistry immunocytochemistry immunofluorescence perox ions channels membrane proteins voltage ligands gated 0.607734806630
13701 Cavβ4 Calcium Channel Monoclonal Antibody (Clone S10-7) - 2009-11-05 0.607734806630 cav-4-calcium-channel-monoclonal-antibody-clone-s10-7 western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC ions channels antibodies epilepsy IGE JME subunits gated voltage-gated ligand-gated ligand voltage 0.607734806630
10009078 CAY10505 328960-84-5 ≥98% 2009-11-04 7.954950276243 cay10505 phosphoinositide 3-kinase immunity autoimmune inflammation PI3Kγ PI3Kα PI3Kβ PI3Kδ casein kinases 2 CK2 phosphorylation PKB/Akt macrophages neutrophil recruitment cancer PI3s T2Ds PI3Ks PI3K.gamma. PI3Kg 7.954950276243
13207 CAY10594 Exclusive 1130067-34-3 ≥98% 2009-06-23 21.809723710576 cay10594 Phospholipase D PLDs PLD1 PLD2 phosphatidic acid PA inhibitors chemotaxis cells migration cancers breast cancer inhibition inhibited 21.809723710576
13146 CAY10603 1045792-66-2 ≥95% 2009-06-18 18.970612645795 cay10603 HDAC 6 inhibitors inhibits inhibition tubulin microtubule pancreatic cancers SAHA HDAC6 HDAC-6 HDACs HDACIs potent selective cells 18.970612645795
13381 CAY10606 1159576-98-3 ≥98% 2009-12-04 64.293687845303 cay10606 5-lipoxygenases 5-LOs leukotrienes LTs LTB4 arachidonic acids inhibitors inhibit neutrophils blood ionophore A23187 formyl peptides fMLP lipopolysaccharides LPS reversed pleurisy inflammation inflammatory inhibition 64.293687845303
13687 CAY10622 Exclusive 1038549-25-5 ≥98% 2010-10-18 4.929631675874 cay10622 Rho kinases ROCK-I ROCK-II inhibitors inhibits inhibition 4.929631675874
15467 CBX3 (human recombinant) New - ≥95% 2014-03-10 0E-12 cbx3-human-recombinant Heterochromatin Protein 1 Homolog γ; HP1-γ; Chromobox Protein Homolog 3 epigenetics chromodomains CSD CBX chromobox histones 3 H3K9me3 proteins recombinant homologs 3 three HECH heterochromatin 1 one gamma .gamma. g γ HP1 modifiers 2 two HP1γ HP1.gamma. HP1gamma HP1g genes regulations formations methylated H3 lysine 9 nine H1 26 H1K26me G9A 185 Nanog genes transcriptions HIV-1 tumors stems cells osteosarcoma 0E-12
10339 CD25 Monoclonal PE Antibody (Clone 143-13) Exclusive - 2010-06-09 15.292058011049 cd25-monoclonal-pe-antibody-clone-143-13 Interleukin-2 receptor α subunit; Tac; IL-2Rα; p55 antibodies antiserum FC flow cytometry immunocytochemistry ICC interleukins 2 IL-2 IL2 cytokines immunochemical immunohistochemistry IHC frozen tissues sections 15.292058011049
10208 CD34 Monoclonal FITC Antibody (Clone ICO-115) - 2008-07-23 29.391712707182 cd34-monoclonal-fitc-antibody-clone-ico-115 antibodies antiserum antisera flow cytometry immunofluorescence FC IF transmembranes glycoproteins leukemias stem cell lines 29.391712707182
10009349 Cell Cycle Phase Determination Kit - 2007-04-20 43.804986187845 cell-cycle-phase-determination-kit assays kits measures measurements microscopy flow cytometry plate readers regulators cells transcription factors DNA proteins division proliferation induction inhibition fixation permeabilization staining sub-G1 G0 G2 S propidium iodide apoptosis cancer cell-based assay cell based assay cba 43.804986187845
14456 CFSE 150347-59-4 ≥90% 2013-09-26 1.733109452736 cfse 5(6)-Carboxyfluorescein diacetate succinimidyl ester cell-permeable dyes cells permeable fluorescein succinimidyl esters fluorescent cell proliferation assay flow cytometry FC stable acetate moieties daughter cells eight 8 generational divisions CFDA-SE CFDASE CFDA SE trace vibrant biology cycles stains indicators 1.733109452736
10009853 CFSE Cell Division Assay Kit - 2010-01-15 67.406646496536 cfse-cell-division-assay-kit derivative carboxyfluorescein diacetate, succinimidyl ester CFDA-SE cells proliferation growth factors receptors surfaces signaling molecules transcription factors DNA deoxyribonucleases proteins divisions cascades human pathological diseases cancers cell-tracing fluorescent fluorescence dyes proliferative activity parent generations daughter acetate groups molecules cleaved background unstained staining CFSE-labeled radioactivity radioactive labeling divisions inductions inhibitors inhibits inhibitions in vitro models flow cytometry fluorochromes fluorescein 67.406646496536
13322 CGP 57380 522629-08-9 ≥95% 2009-08-28 17.130377532228 cgp-57380 MNK1 Inhibitor inhibitors inhibits inhibitions MAPKs MAP kinases interacting interacting-kinase 1 MNK1 p38 JNK1 ERK1/2 PKC Src-like phosphorylation elF4E TNF-a TNF-α TNFα TNFa arsenite anisomycin PMA fetal calf serum 293 cells RAW264.7 toll-like receptors TLR2 HKLM TLR4 LPS TLR6/2 FSL TLR7 imiquimod TLR9 CpG DNA CGP57380 CGP-57380 17.130377532228
13122 CHIR99021 252917-06-9 ≥98% 2011-02-18 217.050946132596 chir99021 CT 99021 GSK-3α GSK-3β inhibitors glucose metabolism insulin diabetes Wnt stem cells mice mouse CHIR-99021 CT-99021 CHIR 99021 CT99021 pyridines glucogen synthesis CHO-IR self-renewal 217.050946132596
10009779 Cholesterol Cell-Based Detection Assay Kit - 2007-05-04 46.900681399632 cholesterol-cell-based-detection-assay-kit Fluorescence Kits Metabolism coronary heart diseases LDL lipoproteins ADHP atherosclerosis fluorescent fluorometric assays cell-based assay cell based assays cba U18666A U 18666A U-18666A 46.900681399632
15106 Cholesterol Sulfate (sodium salt) New 2864-50-8 ≥95% 2013-10-25 2.616908484609 cholesterol-sulfate-sodium-salt SCS; Sodium Cholesteyl Sulfate 1256-86-6 127565-99-5 164266-84-6 sulfolipid sterols steroids cells membranes lipids bilayer liposomes sodium salts endogenous substrates proteins keratinocyte differentiation development epidermal barrier biology synthetics metabolism synthesis stabilizes regulates 2.616908484609
10007290 cis-7-Hexadecenoic Acid 2416-19-5 ≥98% 2006-02-21 2.707882136280 cis-7-hexadecenoic-acid monounsaturated fatty acids cellular membranes autotrophic bacterial genera populations natural environments mining lakes cultures sulfates biofilters sulfide-oxidizing organisms strains Nitrospira nitrates 2.707882136280
10006864 cis-7-Hexadecenoic Acid methyl ester 56875-67-3 ≥98% 2006-02-21 2.358047882136 cis-7-hexadecenoic-acid-methyl-ester cis-7-Hexadecenoate methyl ester esters monounsaturated fatty acids cellular membranes autotrophic bacterial genera populations natural environments mining lakes cultures sulfates biofilters sulfide-oxidizing organisms strains Nitrospira nitrates 2.358047882136
11320 Citrinin 518-75-2 ≥98% 2012-02-21 5.943174953959 citrinin NSC 186 11003-17-1 16051-41-5 mycotoxin food contaminants cytotoxin mycotoxic Balkan nephropathy yellow rice fever apoptosis tubulin polymerization microtubule organization Penicillium citrinum P. citrinum NSC-186 NSC186 5.943174953959
11050 Concanamycin A 80890-47-7 ≥95% 2012-03-21 7.750276243094 concanamycin-a Antibiotic X 4357B; NSC 674620; X 4357B 66771-59-3 NSC674620 NSC-674620 X-4357B X4357B vacuolar H+-ATPase V-type proton pumps inhibitors inhibits inhibition pH lysosomes endosomes V1 V0 domains plecomacrolide antibiotics Streptomyces viral glycoproteins influenza viruses cells 7.750276243094
15502 Concanamycin B New 81552-33-2 ≥95% 2014-01-27 0E-12 concanamycin-b 8-deethyl-8-methyl-Concanamycin A; MCH 210 natural products antibiotics inhibitors cells biology immunology bones research potent ATPases V major histocompatibility complex MHCs 210 MCH210 MCH-210 selective H+ H+-ATPases V V-ATPases acidification vacuolar organelles endosomal transports resorptions CD8 T lymphocytes class II two humans S 45B 0E-12
14951 Concanavalin A 11028-71-0 2013-09-25 2.407438016529 concanavalin-a 12612-33-8 lectin jack beans C. ensiformis canavalia glycoproteins agglutination mitogenesis apoptosis glycolipids affinity chromatography purifications autoimmune hepatitis AIH immune response T cells T-cells cross-links cross links cell-surface surface concanacalin-A Con A ConA Con-A plants immunology biology carbohydrates 2.407438016529
10010096 COX-2 (mouse) Polyclonal FITC Antibody Exclusive - 2008-04-23 22.471012891344 cox-2-mouse-polyclonal-fitc-antibody Cyclooxygenase 2; PGHS2; Prostaglandin H Synthase 2 antibodies prostaglandins thromboxanes prostacyclins arachidonic acids FC flow cytometry ICC immmunocytochemistry WB western blots blotting immunoblotting IF immunofluorescence 22.471012891344
14748 Cyclic Pifithrin-α (hydrobromide) 511296-88-1 ≥95% 2013-08-16 6.915073264472 cyclic-pifithrin-hydrobromide Cyclic PFT-α; Pifithrin-β; PFT-β 60477-34-1 inhibitors cancers neurosciences intracellulars signalings apoptosis cells biology signals transductions autophagy inhibits inhibitions pifithrins pifithrin-a pifithrin-alpha pifithrin-.alpha. pifithrin-α pifithrin-beta pifithrin-β pifithrin-.beta. pifithrin-b β α beta alpha .beta. .alpha. b a h2O2 IGROV-1 IGROV1 IGROV 1 one A2780 A-2780 A 2780 HCT-116 HCT116 HCT 116 H460 H 460 H-460 antimicrotubules anti-microtubule anti microtubule DNA damages UV ultraviolet radiation melanocytes p53 transcription hydrogen peroxide H2O2 growth 6.915073264472
14126 Cycloheximide 66-81-9 ≥95% 2013-06-25 28.495509515039 cycloheximide NSC 185; Naramycin A 4630-76-6 6399-67-3 17974-04-8 21059-09-6 antibiotics inhibitors inhibits inhibitions proteins synthesis eukaryotes translation elongation apoptosis S. griseus Streptomyces cells types molecular biology biologies ribsome profiling profiles translational half-life half life NSCs 185 NSC185 NSC-185 naramycin-A acti-aid actiaid acti aids acti-dione actidione acti dione BR PM TGF actidion CHX cicloheximide FT 3422-2 FT-3422-2 FT3422-2 34222 3422 2 FT-34222 FT-3422 FT34222 FT3422 LDNs LDN97549 LDN-97549 97549 NM-MCD 80 NMMCD-80 naramycin microcapsule D 80 NM-MCU TZA Us 4527 U-4527 U4527 28.495509515039
11321 Cyclopamine 4449-51-8 ≥98% 2012-02-20 31.120965316145 cyclopamine 11-Deoxojervine; Jervine 11051-96-0 26108-61-2 veratraman 11-deoxyjervine 11 deoxyjervine hedgehogs development teratogen cancers smoothened inhibitors cyclopia genes expressions signal transduction inhibits inhibition signaling steroids alkaloids pathways pax7 31.120965316145
11326 Cyclopiazonic Acid 18172-33-3 ≥95% 2012-02-23 29.606266114180 cyclopiazonic-acid NSC 117181 inhibitors SERCA calcium Ca2+-ATPase ATPases smooth muscles endothelial cells endothelium cardiovascular vascular biology cardiology mycotoxins Penicillium Aspergillus NSC117181 NSC-117181 29.606266114180
11327 Cytochalasin A 14110-64-6 ≥98% 2012-07-25 3.414115938135 cytochalasin-a Dehydrophomin; Phomin; NSC 174119 NSC174119 NSC-174119 11032-94-3 11041-99-9 actin polymerization cytoskeleton inhibitors glucose transporter cells biology inhibits inhibition analogs HIV1 HIV HIV-1 1 protease transports tyrosine phosphatase PTP3 PTP-3 PTP 3 dictyostelium activating activates activation STATc STAT-c STAT c cytochalasin-A cytochalasin-b 3.414115938135
11328 Cytochalasin B 14930-96-2 ≥98% 2012-02-22 18.175235464351 cytochalasin-b NSC 107658; Phomin 11032-95-4 11042-65-2 16006-03-4 21476-12-0 inhibitors actin proliferation migration phagocytosis glucose exocytosis cells division chemotaxis inhibits inhibition mycotoxins polymerization NSC-107658 NSC107658 18.175235464351
11329 Cytochalasin C New 22144-76-9 ≥99% 2014-01-24 0.186740331491 cytochalasin-c inhibitors cells biology cytoskeletal research cytochalasins actin filaments polymerization cancers inhibitions inhibits polymerizes movements growths phagocytosis degranulation secretions cultures mice mouse D 11044-50-1 0.186740331491
11330 Cytochalasin D 22144-77-0 ≥95% 2013-06-25 13.383186003683 cytochalasin-d NSC 209835 11032-97-6 25852-72-6 28455-04-1 69401-32-7 zygosporin-A zygosporins A inhibitors cancers cells biology cytoskeletal research inhibits inhibitions cytochalasins D cell-permeable cells permeables filaments polymerizations prevents migrations tumors cells cytochalasin-d NSC-209835 NSCs 209835 NSC209835 fungal fungus fungi metabolites actins movements growths phagocytosis cellular eating drinking degranulations secretions 13.383186003683
11331 Cytochalasin E 36011-19-5 ≥98% 2012-07-24 5.558107734806 cytochalasin-e 12623-99-3 actin polymerization cytoskeleton inhibitors angiogenesis cancer cells biology inhibitions inhibits epoxide-containing epoxide analogs cytochalasin-b cytochalasin b endothelial impairment impairing impairing angiogenesis tumors growth cytochalasin-e 5.558107734806
10568 Cytokeratin Monoclonal APC Antibody (Clone C-11) - 2011-03-04 1.940355169692 cytokeratin-monoclonal-apc-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms flow cytometry FC proteins immunofluorescence IF 1.940355169692
10349 Cytokeratin Monoclonal FITC Antibody (Clone C-11) - 2010-04-14 2.020193370165 cytokeratin-monoclonal-fitc-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms western blots WB flow cytometry FC immunofluorescence IF immunoblotting proteins blotting 2.020193370165
10478 Cytokeratin Monoclonal PE Antibody (Clone C-11) - 2010-10-28 0.943646408840 cytokeratin-monoclonal-pe-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera anti-serum anti serum anti-ser anti sera isoforms flow cytometry FC immunoblotting proteins blotting IF immunofluorescence 0.943646408840
13305 D 4476 301836-43-1 ≥98% 2009-07-29 22.931652788740 d-4476 Casein Kinase I Inhibitor inhibitors inhibits inhibition casein kinases 1 CK1 Ck1δ TGF-β TGFβ type-1 receptors ALK5 PKD1 p38α MAPK kinases phosphorylation FOXO1a RhoB p53 Smad3 D4476 22.931652788740
10007945 D-erythro-Sphinganine 764-22-7 ≥98% 2010-08-10 17.797795077850 d-erythro-sphinganine Dihydro-D-erythro Sphingosine; D-erythro-Dihydrosphingosine ceramide sphingosine sphingosine kinases sphinganine-1-phosphates mycotoxins fumonisins cancers protein kinase C PKC spingosine-1-phosphates cell signaling octadecasphinganine Dihydro-C18-sphingosine SPC 102860 SPC102860 signalling SPC-102860 17.797795077850
10007907 D-erythro-Sphingosine C-18 123-78-4 >98% 2007-01-17 20.824923265807 d-erythro-sphingosine-c-18 (-)-Sphingosine Sphingosines S1P sphingosine-1-phosphates kinases SPHK1 SPHK2 Proliferation cancers inhibits inhibitors inhibition ceramides DAG diacylglycerols cells phophorylation morphogenesis SK1 sphingolipids SK2 anti-proliferative 20.824923265807
10012577 Diallyl Trisulfide 2050-87-5 ≥95% 2009-04-07 8.413363259668 diallyl-trisulfide NSC 651936; DATS garlic hydrogen sulfides H2S cancers tumors smooth muscle cholesterol atherosclerosis donors supresses colon synthesis genes expression adenocarcinomas HCT-15 cells PC-3 xenografts 8.413363259668
11219 DMABA-d10 NHS ester 1175002-05-7 9% deuterated forms (d1-d10) 2012-02-15 0.534069981583 dmaba-d10-nhs-ester GC/MS deuterium deuterateds internal standards LC/MS GC-MS LC-MS mass spectrometry MS phosphatidylethanolamines FAAH fatty acids synthesis PUFA polyunsaturated fatty acyl phospholipids probes electorspray tandem PE lipids markers 0.534069981583
11217 DMABA-d4 NHS ester 1175002-03-5 ≥99% deuterated forms (d1-d4) 2012-02-15 0.213627992633 dmaba-d4-nhs-ester 4-(dimethylamino) Benzoic Acid-d4; N-Succinimidyl 4-(dimethylamino)benzoate-d4; DMABA N-hydroxysuccinimide ester-d4 GC/MS deuterium deuterateds internal standards LC/MS GC-MS LC-MS mass spectrometry MS phosphatidylethanolamines FAAH fatty acids synthesis PUFA polyunsaturated fatty acyl phospholipids probes electorspray tandem PE lipids markers 0.213627992633
11218 DMABA-d6 NHS ester 1175002-04-6 ≥99% deuterated form (d1-d6) 2012-02-07 0.213627992633 dmaba-d6-nhs-ester N-Succinimidyl 4-(dimethylamino)benzoate-d6; 4-(dimethylamino) Benzoic Acid-d6; DMABA N-hydroxysuccinimide ester-d6 GC/MS deuterium deuterateds internal standards LC/MS GC-MS LC-MS mass spectrometry MS phosphatidylethanolamines FAAH fatty acids synthesis PUFA polyunsaturated fatty acyl phospholipids probes electorspray tandem PE lipids markers 0.213627992633
11216 DMABA NHS ester 58068-85-2 ≥98% 2012-01-19 0.320441988950 dmaba-nhs-ester 4-(dimethylamino) Benzoic Acid; DMABA N-hydroxysuccinimide ester; N-Succinimidyl 4-(dimethylamino)benzoate phosphatidylethanolamines FAAH fatty acids synthesis PUFA polyunsaturated fatty acyl phospholipids probes MS mass spectrometry electorspray tandem PE lipids markers 0.320441988950
10008448 D-myo-Inositol-1,2,3,4-tetraphosphate (sodium salt) - ≥98% 2007-06-22 4.131976672805 d-myo-inositol-1-2-3-4-tetraphosphate-sodium-salt 1,2,3,4-IP4 (sodium salt); Ins(1,2,3,4)-P4 (sodium salt) phosphates IP3 transduction InsPs phosphatidylinositols phospholipases C Pleckstrin homology PH domains signalling signaling cells 114418-90-5 4.131976672805
10008453 D-myo-Inositol-1,2,3,5,6-pentaphosphate (sodium salt) - ≥98% 2009-03-02 4.105911602210 d-myo-inositol-1-2-3-5-6-pentaphosphate-sodium-salt Ins(1,2,3,5,6)-P5 (sodium salt); 1,2,3,5,6-IP5 (sodium salt) phytates k. terrigena calcium channel inositosl Ins(1,4,5)P3 26326-85-2 4.105911602210
10008449 D-myo-Inositol-1,2,3,5-tetraphosphate (sodium salt) - ≥98% 2007-06-27 4.529502762431 d-myo-inositol-1-2-3-5-tetraphosphate-sodium-salt 1,2,3,5-IP4 (sodium salt); Ins(1,2,3,5)-P4 (sodium salt) inositols phosphates IP3 transduction InsP phosphatidylinositol phospholipase C Pleckstrin signaling signalling cells homology PH domains 4.529502762431
10008450 D-myo-Inositol-1,2,3,6-tetraphosphate (sodium salt) - ≥98% 2007-06-22 4.529502762431 d-myo-inositol-1-2-3-6-tetraphosphate-sodium-salt 1,2,3,6-IP4 (sodium salt); Ins(1,2,3,6)-P4 (sodium salt) inositols phosphates IP3 transduction InsP phosphatidylinositol phospholipases C Pleckstrin homology PH domains signalling signaling cells 41613-03-0 4.529502762431
10008452 D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt) - ≥98% 2007-06-08 7.311972208271 d-myo-inositol-1-2-4-5-6-pentaphosphate-sodium-salt Ins(1,2,4,5,6)P5 (sodium salt); 1,2,4,5,6-IP5 (sodium salt) IP3 inositols phosphate transduction InsP phosphitidylinositol phospholipase C PLC InsP6 kinase signaling signalling cells 26326-86-3 7.311972208271
10008451 D-myo-Inositol-1,2,4,5-tetraphosphate (sodium salt) - ≥98% 2007-06-22 4.529502762431 d-myo-inositol-1-2-4-5-tetraphosphate-sodium-salt Ins(1,2,4,5)P4 (sodium salt); 1,2,4,5-IP4 (sodium salt) phosphates IP3 transduction InsPs phosphatidylinositols phospholipases C Pleckstrin homology PH domains signalling signaling cells 117142-45-7 4.529502762431
10008444 D-myo-Inositol-1,2,5,6-tetraphosphate (sodium salt) - ≥98% 2007-06-06 4.529502762431 d-myo-inositol-1-2-5-6-tetraphosphate-sodium-salt Ins(1,2,5,6)P4 (sodium salt); 1,2,5,6-IP4 (sodium salt) inositol phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC Grp-1 Pleckstrin homology PH domain signalling signaling cells 28841-60-3 4.529502762431
10007780 D-myo-Inositol-1,2,6-triphosphate (sodium salt) - ≥98% 2006-01-13 16.318867403315 d-myo-inositol-1-2-6-triphosphate-sodium-salt Ins(1,2,6)-P3; 1,2,6-IP3 phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels D/L racemic Xenopus oocytes 16.318867403315
10008439 D-myo-Inositol-1,2-diphosphate (sodium salt) 208584-51-4 ≥98% 2008-01-17 11.191566692975 d-myo-inositol-1-2-diphosphate-sodium-salt Ins(1,2)P2 (sodium salt); 1,2-IP2 (sodium salt) inositols phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC signaling signalling PtdIns initiating Ca2+ calcium release phosphoinositols 11.191566692975
10007784 D-myo-Inositol-1,3,4,5,6-pentaphosphate (sodium salt) - ≥98% 2006-01-13 13.884254143646 d-myo-inositol-1-3-4-5-6-pentaphosphate-sodium-salt Ins(1,3,4,5,6)P5 (sodium salt); 1,3,4,5,6-IP5 (sodium salt) phosphoinositides 3-kinases PI3-K/Akt phosphates IP3 signals transductions cells growh proliferation anticancers agents isomers InsP phosphitidylinositols phospholipases messengers cellular PKB apoptosis ovarian lung breast antiangiogenic in vitro capillary tubes HUVEC antitumor xenografts nude mice PH domains Grp1 13.884254143646
10007781 D-myo-Inositol-1,3,5-triphosphate (sodium salt) - ≥98% 2006-01-11 11.154165131983 d-myo-inositol-1-3-5-triphosphate-sodium-salt Ins(1,3,5)P3 (sodium salt); 1,3,5-IP3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels meso compounds Xenopus oocytes 11.154165131983
10008443 D-myo-Inositol-1,3-diphosphate (sodium salt) 208584-52-5 ≥98% 2006-12-21 16.444728631784 d-myo-inositol-1-3-diphosphate-sodium-salt 1,3-IP2 (sodium salt); Ins(1,3)-P2 (sodium salt) phosphates IP2 signals transductions InsP phosphatidyls inositols messengers cellular phospholipases PLC ER endoplasmic reticulum calcium Ca2+ dephosphorylation 16.444728631784
10007783 D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) 157542-47-7 ≥98% 2006-01-13 17.536155198393 d-myo-inositol-1-4-5-6-tetraphosphate-sodium-salt Ins(1,4,5,6)-P4; 1,4,5,6-IP4 oligophosphates isomers IP3 signals transductions InsP phosphatidylinositols phospholipases intestinal epithelial cells strains incubation times Salmonella epidermal growth factor EGF PI3-kinases cellular calcium Ca2+ Ca++ channels D/L racemic mixture Xenopus oocytes 17.536155198393
10008205 D-myo-Inositol-1,4,5-triphosphate (sodium salt) 141611-10-1 ≥98% 2006-01-30 17.808602534936 d-myo-inositol-1-4-5-triphosphate-sodium-salt Ins(1,4,5)P3; 1,4,5-IP3 phosphates IP3 signals transductions InsP phosphitidylinositols Ins(1,4,5)P3 phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels analogs agonists rat hepatic receptors 17.808602534936
10008427 D-myo-Inositol-1,4,6-triphosphate (sodium salt) 157380-18-2 ≥98% 2007-06-22 12.591540055248 d-myo-inositol-1-4-6-triphosphate-sodium-salt 1,4,6-IP3; Ins(1,4,6)-P3 phosphates IP3 transduction InsPs phosphatidylinositols phospholipase C PLC signalling signaling cells 114418-85-8 12.591540055248
10008438 D-myo-Inositol-1,4-diphosphate (sodium salt) - ≥98% 2007-01-08 21.380718232044 d-myo-inositol-1-4-diphosphate-sodium-salt Ins(1,4)-P2 (sodium salt); 1,4-IP2 (sodium salt) phosphates IP2 signals transductions InsP phosphatidyls inositols messengers cellular phospholipases PLC ER endoplasmic reticulum calcium Ca2+ dephosphorylation signalling 74465-19-3 21.380718232044
10008422 D-myo-Inositol-1,5,6-triphosphate (sodium salt) 120965-76-6 ≥98% 2009-08-04 25.940156537753 d-myo-inositol-1-5-6-triphosphate-sodium-salt 1,5,6-IP3 (sodium salt); Ins(1,5,6)-P3 (sodium salt) phosphates IP2 signal transduction cells cycling apoptosis differentiation motility InsP phosphatidyl inositol IP3 second messengers trisphosphates PtdIns phosphatidylinositol D-myos PIPS 25.940156537753
10008441 D-myo-Inositol-1,5-diphosphate (sodium salt) - ≥98% 2007-06-13 36.680276243094 d-myo-inositol-1-5-diphosphate-sodium-salt Ins(1,5)-P2 (sodium salt); 1,5-IP2 (sodium salt) inositol phosphates IP3 signaling transduction signalling cells InsP phosphitidylinositols phospholipases cPLC 114418-78-9 36.680276243094
9001248 D-myo-Inositol-1-phosphate (cyclohexyl ammonium salt) - ≥95% 2012-10-25 8.516187845303 d-myo-inositol-1-phosphate-cyclohexyl-ammonium-salt Ins(1)P1 (cyclohexyl ammonium salt); 1-IP1 (cyclohexyl ammonium salt) 106032-59-1 cells signaling signal transduction inositols InsP phosphates intracellular 8.516187845303
10007777 D-myo-Inositol-1-phosphate (sodium salt) - ≥98% 2006-01-13 21.442786985880 d-myo-inositol-1-phosphate-sodium-salt 1-IP1 (sodium salt); Ins(1)P1 (sodium salt) phosphates IP1 signals transductions InsP phosphatidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels meso compounds Xenopus oocytes 15421-51-9 956031-56-4 21.442786985880
10008456 D-myo-Inositol-2,3,4,5-tetraphosphate (ammonium salt) - ≥98% 2007-06-25 31.048379373849 d-myo-inositol-2-3-4-5-tetraphosphate-ammonium-salt Ins(2,3,45)-P4 (ammonium salt); 2,3,4,5-IP4 (ammonium salt) inositol phosphates IP3 signals transduction InsP phosphitidylinositols phospholipases cPLC signaling signalling 114418-93-8 31.048379373849
10008455 D-myo-Inositol-2,3,5,6-tetraphosphate (sodium salt) - ≥98% 2009-02-26 2.897297421730 d-myo-inositol-2-3-5-6-tetraphosphate-sodium-salt 2,3,5,6-IP4 (sodium salt); Ins(2,3,5,6)-P4 (sodium salt) Inositols phosphates K. terrigena phytate calcium channels D-Ins(2,3,5,6)P4 D-Ins(1,2,3,5,6)P5 IPs PtdIns PIs 11418-91-6 2.897297421730
10008423 D-myo-Inositol-2,3,5-triphosphate (ammonium salt) - ≥98% 2008-09-30 7.438606507059 d-myo-inositol-2-3-5-triphosphate-ammonium-salt 2,3,5-IP3 (ammonium salt); Ins(2,3,5)P3 (ammonium salt) phosphates IP3 signal transduction InsP phosphitidylinositols phospholipase C PLC cell signaling calcium channels 114418-82-5 7.438606507059
10007779 D-myo-Inositol-2,4,5-triphosphate (sodium salt) - ≥98% 2006-01-13 10.511316758747 d-myo-inositol-2-4-5-triphosphate-sodium-salt Ins(2,4,5)P3 (sodium salt); 2,4,5-IP3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols Ins(1,4,5)P3 phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels analogs agonists rat hepatic receptors 10.511316758747
10008424 D-myo-Inositol-2,5,6-triphosphate (sodium salt) - ≥98% 2008-10-10 7.438606507059 d-myo-inositol-2-5-6-triphosphate-sodium-salt 2,5,6-IP3 (sodium salt); Ins(2,5,6)P3 (sodium salt) phosphates IP3 signal transduction InsP phosphitidylinositols phospholipase C PLC cell signaling calcium channels L-myo-Inositol-2,4,5-triphosphate (sodium salt) 136735-76-7 7.438606507059
10007782 D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) - ≥98% 2006-01-13 13.643613761928 d-myo-inositol-3-4-5-6-tetraphosphate-sodium-salt Ins(3,4,5,6)-P4; 3,4,5,6-IP4 oligophosphates isomers kinases IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels Xenopus oocytes 13.643613761928
10008425 D-myo-Inositol-3,4,5-triphosphate (sodium salt) - ≥98% 2007-06-05 11.104389195825 d-myo-inositol-3-4-5-triphosphate-sodium-salt Ins(3,4,5)-P3; 3,4,5-IP4 inositols phosphate IP3 signal transduction InsP phosphitidylinositol phospholipase C PLC 112791-62-5 11.104389195825
10007778 D-myo-Inositol-3-phosphate (sodium salt) - ≥98% 2006-01-13 19.711009821976 d-myo-inositol-3-phosphate-sodium-salt 3-IP1 (sodium salt); Ins(3)P1 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels dephosphorylation 2831-74-5 956031-55-3 19.711009821976
10008418 D-myo-Inositol-4,5-diphosphate (sodium salt) - ≥98% 2007-01-04 21.162531686708 d-myo-inositol-4-5-diphosphate-sodium-salt 4,5-IP2 (sodium salt); Ins(4,5)-P2 (sodium salt) IP3 myo-inositols Ins(1,4,5)P3 Ins(4,5)P2 cells signaling transduction diphosphates salts InsPs phosphorylation receptors messengers inositol-4,5-biphosphate hydrolysis intracellular calcium PLC phospholipases signalling 69256-54-8 21.162531686708
10008437 D-myo-Inositol-4-phosphate (ammonium salt) 142760-33-6 ≥98% 2006-10-18 13.462713682158 d-myo-inositol-4-phosphate-ammonium-salt Ins(4)P1 (ammonium salt); 4-IP1 (ammonium salt) phosphates IP4 signals transductions InsP phosphatidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels dephosphorylation polyphosphates monophosphatase PtdIns 13.462713682158
14062 Dynasore 304448-55-3 ≥95% 2013-02-07 5.221657458564 dynasore receptors biochemistry infectious disease inhibitors inhibits inhibitions neuroscience cells biology endocytosis infections secretion receptors biology cell-permeable dyamin1 dyamin2 dyamins dyamin-1 dyamin-2 mitochondrial Drp1 Drp-1 GTPase clathrin neurotransmitters secreted cytokines 5.221657458564
13151 (E)-C-HDMAPP (ammonium salt) Exclusive 933030-60-5 ≥95% 2009-09-25 42.599723756906 -e-c-hdmapp-ammonium-salt (E)-1-Hydroxy-2-Methylbut-2-enyl 4-Diphosphate The pyrophosphonate form of (E)-HDMAPP; much more stable than (E)-HDMAPP in solution and in vascular circulation; potently stimulates the synthesis of TNF-α by γδ-T lymphocytes with an IC50 of 0.91 nM; also significantly increases the number of circulating γδ-T cells in vivo 42.599723756906
13541 eIF3A Polyclonal Antibody - 2010-07-09 0E-12 eif3a-polyclonal-antibody Eukaryotic Translation Initiation Factor 3A eIF-3A eIF proteins antibodies western blots blotting immunoblotting WB immunohistochemistry IHC eIF3B K7 cytokeratin 7 40S ribsome RNA tRNA mRNA cell biology 0E-12
13542 eIF3B Polyclonal Antibody - 2010-07-09 0.564309392265 eif3b-polyclonal-antibody Eukaryotic Translaction Initiation Factor 3B eIF acidic protein RRM RNA recognition motif 40S sibosomal mRNA tRNAi tissues antibodies western blots blotting immunoblotting WB IHC immunohistochemistry cell biology 0.564309392265
13544 eIF3D Polyclonal Antibody - 2010-07-09 0E-12 eif3d-polyclonal-antibody Eukaryotic Translation Initiation Factor 3D antibodies western blots blotting immunoblotting WB eIF3-D eIF-3D eIF 3D proteins subunits 40S ribosomol 60S GTP methionyl tRNA mRNA RNA ATM ATR cell biology 0E-12
13537 eIF3G Polyclonal Antibody (aa 200-250) - 2009-10-12 0E-12 eif3g-polyclonal-antibody-aa-200-250 Eukaryotic Translation Initiation Factor 3G antibodies immunoblotting blotting western blots WB IHC immunohistochemistry peptides RNA associated recognition motif RRM ubiquitously expressed 0E-12
13545 eIF3G Polyclonal Antibody (aa 50-100) - 2010-07-21 0E-12 eif3g-polyclonal-antibody-aa-50-100 Eukaryotic Translation Initiation Factor 3G antibodies eIF-3G eIF 3G western blots blotting immunoblotting WB immunohistochemistry IHC RNA proteins RRM recognition motif eIF3K tRNAi mRNA rRNA RNA-associated G family 0E-12
13547 eIF4A1 Polyclonal Antibody - 2010-07-27 0E-12 eif4a1-polyclonal-antibody Eukaryotic Translation Initiation Factor 4A1 antibodies western blots blotting immunoblotting WB RNA DEAD box helicase eIF4F kinase MNK1 eIF4B eIF4G eIF4E PABC1 eIF4A2 mRNAs 40S ribosomal tissues 0E-12
13550 eIF4B Polyclonal Antibody (aa 150-200) - 2010-09-07 0E-12 eif4b-polyclonal-antibody-aa-150-200 Eukaryotic Translation Initiation Factor 4B antibodies eIF eukarytoic translation initiations factors RNA RRM recognition domains RNP-CS N-terminal N-terminus DRYG aspartic acids argine tyrosine glycine DEAD box inhibitory inhibition inhibits western blots immunoblotting WB mRNAs 0E-12
15137 eIF4E (human recombinant) New - ≥90% 2014-02-28 0E-12 eif4e-human-recombinant mRNA Cap-binding Protein; Eukaryotic Translation Initiation Factor 4E; eIF-4F 25 kDa subunit Translations mRNA 5'-cap cancers inititaion factors MCM eukaryotic messengers RNA mRNA four F 4E E caps structures proteins synthesis mnk1 mitogen activated mitogen-activated kinases kinase-interacting interacting oncogene oncogenic humans malignancy malignancies breast colon heads necks carcinomas cells biology recombinant 0E-12
15564 eIF4E (human recombinant; GST-tagged) New - ≥85% 2014-02-28 0E-12 eif4e-human-recombinant-gst-tagged Eukaryotic Translation Initiation Factor 4E; mRNA Cap-binding Protein; eIF-4F 25 kDa subunit translations mRNA 5'-cap cancers initiation factors eukaryotic messengers RNA mRNA four F 4E E caps structures proteins synthesis mnk1 mitogen activated mitogen-activated kinases kinase-interacting interacting oncogene oncogenic humans malignancy malignancies breast colon heads necks carcinomas cells biology recombinant 0E-12
10009798 EX-527 49843-98-3 ≥98% 2009-10-23 19.116556169428 ex-527 sirtuins SIRT1 histones deacetylase HDAC energy metabolism inflammation inhibitors p53 DNA damage 848193-68-0 848193-69-1 ex527 ex 527 19.116556169428
10010019 FABP2 Polyclonal Antibody - 2007-10-02 5.898780584056 fabp2-polyclonal-antibody I-FABP; Fatty Acid Binding Protein 2; Intestinal-Fatty Acid Binding Protein WB western blots fatty acids FABPs lipophilic ligands metabolism polymorphism FABP2 IFABP obesity diabetes antibodies antiserum diabetic antisera atherosclerosis endocrinology blotting immunoblotting 5.898780584056
15218 FCCP New 370-86-5 ≥98% 2013-11-05 17.426234653161 fccp Trifluoromethoxy carbonylcyanide phenylhydrazone carbonyl cyanide-p-trifluoromethoxyphenylhydrazone FCCP mitochondira uncoupler oxidative phosphorylation ATP synthesis proton gradient microtubule depolymerization cells biology mitochondrial proteins FCCCP 17.426234653161
13563 FIPI 939055-18-2 ≥98% 2010-03-24 22.593425375756 fipi 5-Fluoro-2-Indolyl des-Chlorohalopemide Phospholipases D PLD phosphatidic acids PA Ras activation cells spreading stress fiber formation chemotaxis membrane vesicles trafficking halopemide inhibitors inhibits inhibition PLD1 PLD2 F-actin cytoskeletons inflammation arthritis Pharmascience Brand of Domperidone Maleate Stadapharm Brand of Domperidone Maleate Ratiopharm Brand of Domperidone Maleate Taxandria Brand of Domperidone Maleate Novopharm Brand of Domperidone Maleate Nu-Pharm Brand of Domperidone Maleate Nu Pharm Brand of Domperidone Maleate Apotex Brand of Domperidone Maleate Hexal Brand of Domperidone Maleate Aliud Brand of Domperidone Maleate Teva Brand of Domperidone Maleate Pierre Fabre Brand of Domperidone Gry Brand of Domperidone Maleate Rottapharm Brand of Domperidone Monohydrochloride, Domperidone Domperidone Monohydrochloride Janssen Brand of Domperidone Domperidone Maleate (1:1) Maleate, Domperidone Domperidone Maleate Gamir Domperidona Stada Domperidon ratio-Domperidone ratio Domperidone Hexal Domperidon Domperidona Gamir Novo-Domperidone Novo Domperidone Domperidon Stada Domperidon Hexal PMS-Domperidone PMS Domperidone Domperidon-TEVA Domperidon TEVA Apo-Domperidone Apo Domperidone Nu-Domperidone Nu Domperidone Domperidon AL Domperidone Gastrocure Domperidon R-33,812 Nauzelin Motilium R-33812 R33,812 Péridys Domidon R33812 22.593425375756
13179 FKGK 11 1071000-98-0 ≥98% 2009-06-30 6.697062615101 fkgk-11 Phospholipases A2 iPLA2 inhibitors signal transduction inhibition PLAs 6.697062615101
13254 FTY720 phenoxy-biotin Exclusive - ≥95% 2009-10-28 54.652223756906 fty720-phenoxy-biotin sphingosine-1-phosphate S1P receptors S1P1 S1P3 S1P4 S1P5 immunosupression immune modulators transporters cPLA2 cytosolic phospholipase A2 biotins biotinylated biotinamide 54.652223756906
14591 Fura-2-Acetoxymethyl ester 108964-32-5 ≥95% 2013-06-04 11.370854376464 fura-2-acetoxymethyl-ester Fura-2AM 120065-52-3 dyes stains fluorescents probes cells biology biologies fluorescences fura-2-acetoxymethyl esters intracellular indicators fura-2 calciums fura2 fura 2 2A fura-2A acetoxymethyls fura-2AM noninvasives indicates UV lights light-excitable excitables cells membranes cellular esterases pentacrboxylates Ca2+ spectral properties concentrations lows highs conditions excitations wavelengths emissions variables artifacts images 11.370854376464
15366 Fura-PE3-Acetoxymethyl ester New 172890-84-5 ≥95% 2014-01-08 87.046040515653 fura-pe3-acetoxymethyl-ester Fura-2 Leakage Resistant; Fura-PE3/AM fluorescences dyes stains indicators fluorescents probes cells biology intracellular signaling leaks leak-resistant calcium fura PE3 acetoxymethyl esters AMs UVs LRs leakage resistant 87.046040515653
14965 Furin Inhibitor I 150113-99-8 ≥95% 2013-10-15 8.576336086648 furin-inhibitor-i Decanoyl-Arg-Val-Lys-Arg-CMK decanoyl-Arg-Val-Lys-Arg-CMK decanoyl-Arg-Val-Lys-Arg-chloromethylketone dec-RVKR-CMK TACE decanoyl Arg Val Lys Arg CMKs chloromethylketones chloromethyl ketones chloro methyl inhibitors inhibits inhibitions decanoyl RVKR dec decanoyl-RVKR- dec-CMK furins proproteins pro-proteins pro proteins convertases antiviral inflammation anti-viral anti viral inhibitor-1 1 one selective irreversible cell-permeable cells permeable SPCs SPC1 SPC-1 SPC2 SPC-2 PC2 PC-2 PCs 2 two SPC2/PC2 SPC3 SPC-3 3 three PC3 PC-3 SPC3/PC1/PC3 PC-1 PC1 SPC4 SPC-4 four 4 PACE4 PACEs PACE-4 SPC4/PACE4 SPC-6 6 six SPC6 PC5 PC-5 five 5 PC6 PC-6 SPC6/PC5/PC6 SPC7 SPC-7 seven 7 LPCs PC7 PC-7 PC8 PC-8 8 eight SPC/LPC/PC7/PC8 inflammatory MMPs MMP-2 MMP2 infectious diseases biology competetive glycoproteins pro-MMP-2 8.576336086648
13355 Geldanamycin 30562-34-6 ≥98% 2010-07-29 12.101356660528 geldanamycin NSC 122750 NSC 212518 antibiotics heat shock proteins 90 Hsp90 GRP94 gp96 genes expression cells proliferation apoptosis angiogenesis c-jun adenocarcinoma cancers AP-1 steroids receptors 2,5-Cyclohexadiene-1,4-Diones 1,4-Benzoquinones 1,2-Benzoquinones p-Benzoquinones-o-Benzoquinones Benzoquinones Benzodiones Quinones geldanomycin GDM NSC122750 NSC-122750 NSC 122750 AC-6794 BRN 1633093 geldanamicin 30562-34-6 antibiotic U29135 U-29135 U 29135 AC1NQZ81 ligands GRP94 Hsp 90 12.101356660528
600360 Glutathione Cell-Based Detection Kit (Blue Fluorescence) - 2011-01-11 56.682006708760 glutathione-cell-based-detection-kit-blue-fluorescence GSH Cell-Based Detection Kit (Blue Fluorescence) kits assy kits measuring measurement glutathiones GSH tripeptides thiols animal cells oxygen radicals hydrogen peroxides H2O2 oxidative stress anti-oxidant antioxidents environmental toxins damages mitochondrial degeneration age-related aging apoptosis intracellular levels indicators cell-permeable dyes monochlorobimane MCB high-throughput screening 56.682006708760
10010013 Glutathione S-Transferase Polyclonal Antibody - 2007-09-26 63.714350828729 glutathione-s-transferase-polyclonal-antibody GST polyclonal antibody recombinant proteins enzymes SDS-PAGE cellular purifications WB western blots blotting immunoblotting IP immunoprecipitation 63.714350828729
600450 Glycolysis Cell-Based Assay Kit Exclusive - 2011-08-18 102.473010888178 glycolysis-cell-based-assay-kit CBAs assays kits measures colorimetric colorimetric-based L-lactate culture media mediums cellular metabolic pathways glucose metabolisms cells ATP adenosines triphosphates oxygen exercise erythrocytes mitochondria glucoeogenesis intracellular molecules amino acids insulin glycolytic neurons aerobic energy muscles anaerobic cancers lactate pyruvate tricarboxylic acids cycles oxidizes carbon dioxide CO2 water H2O tumor aggressiveness embryonic stem activity hypoxia-inducible transcriptional factors HIF-1 extracellular inhibition inhibits inhibitors chemotherapeutic strategies strategy metabolomic drugs discovery anticancer 102.473010888178
10136 GPR17 (C-Term) Polyclonal Antibody - 2010-01-19 18.340578978241 gpr17-c-term-polyclonal-antibody G Protein-Coupled Receptor 17 proteins receptors antibodies western blots WB ICC signals signaling nucleotides CysLTs amino acids blotting immunoblotting FC flow cytometry immunocytochemistry cysteinyl leukotrienes 18.340578978241
11569 GSK 1059615 958852-01-2 ≥98% 2012-03-15 13.711522682903 gsk-1059615 Phosphatidylinositols PI 3-kinases α PI3Ks PI3Kα PI3Ka PI3K.alpha. inhibits inhibitors inhibition thiazolidinediones cells growth human cancers ATP-competitive p110α p110.alpha. p110a E542K E545K H1047R BT474 tumors xenografts MAPKs signaling biology signals transductions 13.711522682903
11931 GSK 4112 1216744-19-2 ≥98% 2012-09-20 2.492389502762 gsk-4112 REV-ERBα nuclear hormone receptors circadian rhythm adipogenesis lipids metabolisms inflammation hemes NCoR HDAC3 transcriptional repression agonists gluconeogenesis GSK4112 GSK-4112 REVERBα inhibits inhibitors inhibiting bmal1 ovaries metabolism 2.492389502762
12073 GSK-J4 (hydrochloride) - ≥95% 2012-12-07 23.002569060773 gsk-j4-hydrochloride 1373423-53-0 epigenetics demethylase histones JMJD3 cells differentiation developments inflammation cancers GSK-J1 pro-drug prodrugs H3 lysine 27 H3K27 H3K-27 GSKJ1 GSKs J1 GSKJ4 J4 inhibitors inhibits inhibitions macrophages reduce LPS induce induced proinflammatory inflammatory pro pro-inflammatory cytokines TNF.alpha. TNF-.alpha. TNF .alpha. TNF-alpha TNF-a TNF-α TNFalpha TNFa TNFα alpha α HCl 23.002569060773
13345 GYY 4137 Exclusive 106740-09-4 ≥95% 2009-07-31 74.597348066297 gyy-4137 hydrogen sulfides H2S gaseous mediators nitric oxides NOs donors vasodilator antihypertensive anti-hypertensive rats spontaneously hypertensive hypertension models endotoxic shock TNF-α TNFα TNF α TNF-a TNFa IL-1b IL1b IL-1β IL1β IL-6 IL6 NFkB NF-kB NF-κB NFκB iNOS COX-2 COX2 PGE2 110-91-8 106740-08-3 74.597348066297
10010559 HA-1077 (hydrochloride) 203911-27-7 ≥98% 2008-09-03 27.289810536301 ha-1077-hydrochloride protein kinase inhibitors inhibits inhibition ROCK-II ROCKII PRK2 MSK1 MAPKAP-K1b vasodilation hypertension diabetes renal nephropathy cancers 105628-07-7 AT877 AT 877 hydrochloride dihydrochloride monohydrochloride HCl HA1077 HA 1077 Fasudil Eril 27.289810536301
13205 Halopemide Exclusive 59831-65-1 ≥98% 2009-04-21 25.500994397921 halopemide NSC 354856; R34301 inhibitors phospholipases D PLD PLD1 PLD2 dopamine receptors inhibits inhibition potent cells DP nueraleptic 25.500994397921
13705 HCN1 Cyclic Nucleotide-gated Channel Monoclonal Antibody (Clone S70-28) - 2009-12-01 0E-12 hcn1-cyclic-nucleotide-gated-channel-monoclonal-antibody-clone-s70-28 antibodies western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC ions channels HCN-1 HCN 1 0E-12
13707 HCN2 Cyclic Nucleotide-gated Channel Monoclonal Antibody (Clone S71-37) - 2009-12-01 0E-12 hcn2-cyclic-nucleotide-gated-channel-monoclonal-antibody-clone-s71-37 antibodies western blots blotting immunoblotting WB immunohistochemistry IHC ions channels HCN-2 HCN 2 ICC immunocytochemistry immunoprecipitation IP 0E-12
13708 HCN3 Cyclic Neuclotide-gated Channel Monoclonal Antibody (Clone S141-28) - 2009-12-01 0E-12 hcn3-cyclic-neuclotide-gated-channel-monoclonal-antibody-clone-s141-28 antibodies western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC ions channels HCN-3 HCN 3 0E-12
13709 HCN4 Cyclic Nucleotide-gated Channel Monoclonal Antibody (Clone S114-10) - 2009-12-02 0E-12 hcn4-cyclic-nucleotide-gated-channel-monoclonal-antibody-clone-s114-10 antibodies western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC ions channels HCN-4 HCN 4 hyperpolarization-activated cation gene family hyperpolarization activated activity activates 0E-12
16834 Hexadecanal-d5 - ≥99% deuterated forms (d1-d5) 2009-03-02 73.315000000000 hexadecanal-d5 16-Hexadecanal; Palmitaldehyde deuterated deuterium sphingosine-1-phosphate S1P palmitic acids S1P lyase 1 plasmalogen cell proliferation GC/MS GC-MS LC/MS LC-MS mass spectrometry 73.315000000000
10006910 HIF-1α Transcription Factor Assay Kit - 2007-10-31 67.266913970008 hif-1-transcription-factor-assay-kit Hypoxia Inducible Factor-1α tf HIF-1alpha factors HIF1.alpha. cancers basic-helix-loop-helix bHLH cellular oxygen homeostasis cells tissues ischemia infections embryos tumors drugs target breast prostate cardiovascular diseases nuclear extracts whole lysates assays kits ELISAs enzyme-linked immunosorbent double stranded dsDNA HIF1 HIF1alpha HIF1 alpha HIF-1 alpha 67.266913970008
13784 Histone H3.3 Polyclonal Antibody - 2010-05-07 3.605914671577 histone-h3-3-polyclonal-antibody H3F3B; H3.3A; H3.3B; H3F3A histones antibodies immunohistochemistry IHC western blotting blots immunoblotting WB H2A H2B H3 H4 H-2A H-2B H-3 H-4 H 2A 2B 3 4 proteins nuclear DNA cells biology chromatin research epigenetics genes regulation modification histones 3.605914671577
15547 Hoechst 33342 (hydrochloride) New 875756-97-1 ≥98% 2014-03-18 0E-12 hoechst-33342-hydrochloride Bisbenzimide; NSC 334072; HOE 33342 23491-52-3 fluorescent dyes stains probes supravital fluorescence DNA counterstain nuclear nuclei cells cycles apoptosis morphology DNA probes Hoechst HCl Hoechst-33342 cell-permeable permeable benzimidazole binds bindings binder adenine thymine blue apoptotic NSCs 334072 NSC-334072 NSC334072 HOEs HOE-3342 HOE3342 Hos 342 Ho-342 Ho342 probes FC flow cytometry indicators minor grooves rich sequences emits bound double stranded markers nuclear morphology 0E-12
15159 HQNO New 341-88-8 ≥98% 2013-11-01 7.777777777778 hqno KF8940; N-oxo-2-heptyl-4-Hydroxyquinoline; Pyo II 1401-​06-​5 1509-​87-​1 respiratory chains inhibitors inhibits inhibitions mitochondrial complex complexes I III NADH oxidase NADH:ubiquinone-1 oxidoreductase protons pumps reduce oxygen probing probed electrons sodium translocation cells biology ions channels blockers KFs KF8940 KF-8940 PyoII Pyo-II 7.777777777778
10011384 Hsc70 (Hsp73) Polyclonal Antibody - 2008-03-26 11.487487812804 hsc70-hsp73-polyclonal-antibody Heat Shock Cognate 70 heat shock stress protein antibodies antiserum WB immunoblotting western blots immunoprecipation immunofluorscence IP IF blotting 11.487487812804
10011383 Hsp40 Polyclonal Antibody - 40 kDa 2008-03-26 15.482956931924 hsp40-polyclonal-antibody HDJ1; Heat Shock Protein 40 DnaJ WB translation folding unfolding translocation degradation heat shock stress chaperone antibodies antiserum Hsps immunoblotting western blots blotting 15.482956931924
10011422 Hsp70 Monoclonal FITC Antibody (Clone C92) - >98% 2008-04-02 13.159431728492 hsp70-monoclonal-fitc-antibody-clone-c92 Heat Shock Protein 70 DnaJ translation folding unfolding translocation degradation heat shock stress chaperone antibodies antiserum flow cytometry FC proteins 13.159431728492
13347 IBMX 28822-58-4 ≥98% 2009-10-27 224.518263471435 ibmx Isobutylmethylxanthine; 1-Methyl-3-Isobutylxanthine; NSC 165960 inhibitor cAMP cGMP phophodiesterases PDE1 PDE2 PDE3 PDE4 PDE5 PDE7 PDE11 PDE8A PDE8B PDE9 cyclic-nucleotides methylxanthines caffeine theophylline adenosine receptors antagonist SC 2964 SC-2964 SC2964 IMX NSC165960 NSC-165960 xanthine 224.518263471435
10343 IgG1 Isotype Control FITC Monoclonal Antibody (Clone MOPC-21) - 2013-01-09 1.171307550644 igg1-isotype-control-fitc-monoclonal-antibody-clone-mopc-21 IgG1κ Isotype Control FITC; IgG1κ Fluorescein Isotype Control FITC fluorescein conjugaged MOPC21 MOPC 21 control IgG1 IFM immunofluorescence microscopy antibodies hybridoma MOPC21 MOPCs 1.171307550644
13314 Indirubin-3'-monoxime 160807-49-8 ≥98% 2009-07-15 13.841010823333 indirubin-3-monoxime glycogen synthase kinase-3β GSK-3β tau proteins Alzheimer's diseases cyclin-dependent kinases CDK Cdk1 cyclin A B E D1 Cdk4 Cdk2 Cdk5 p35 growth proliferation synchronization cells arrest G2/M phases phosphorylation inhibits inhibition inhibitors 13.841010823333
10004974 Ionomycin 56092-81-0 ≥98% 2011-09-30 22.853964088397 ionomycin ionophores calcium transport streptomyces conglobatus intracellular cytokines membranes stores biological SQ23377 SQ-23377 SQ 23377 D10.251.355.391 22.853964088397
11932 Ionomycin (calcium salt) 56092-82-1 ≥98% 2012-10-31 16.338287292817 ionomycin-calcium-salt 1214981-98-2 56092-81-0 Ionophore calcium transports Streptomyces conglobatus S. intracellular levels membranes cytokines salts 16.338287292817
10617 IU1 314245-33-5 ≥98% 2011-01-31 13.965508901166 iu1 inhibitors ubiquitin proteasomes proteins degradation oxidative injury inhibited inhibition 13.965508901166
13951 IWP-2 686770-61-6 ≥98% 2013-06-26 21.290839779005 iwp-2 Inhibitor of Wnt Production-2 develops Wnt signalings cancers embryonic development stems cells β-catenin beta-catenin .beta.-catenin beta catenins inhibitors Porcupines develops IWPs 2 IWP2 IWP-2 in vitro membranes membrane-bound bounds O-acyltransferase palmitoylating proteins blocks blockage blocking LRP6 exo endo inhibits inhibitions disheveled Dvl2 signals transductions intracellular biology productions pathways activity O acyltransferases ability secretions Wnt-dependent dependents phosphorylations LDLs receptor-related 6 related scaffolds Dishevelled preventing accumulations cardiomyocytes generations humans secreted tissues homeostasis tumorigenesis cascades genes transcriptions 21.290839779005
13952 IWP-2-V2 877618-79-6 ≥98% 2013-06-27 8.309447513812 iwp-2-v2 Inhibitor of Wnt Production-2-V2 develops Wnt signalings cancers embryonic development stems cells β-catenin beta-catenin .beta.-catenin beta catenins inhibitors Porcupines develops IWPs 2 V2 IWP2V2 IWP-2-V2 IWP-2V2 in vitro membranes membrane-bound bounds O-acyltransferase palmitoylating proteins blocks blockage blocking LRP6 exo endo inhibits inhibitions disheveled Dvl2 signals transductions intracellular biology productions pathways activity O acyltransferases ability secretions Wnt-dependent dependents phosphorylations LDLs receptor-related 6 related scaffolds Dishevelled preventing accumulations cardiomyocytes generations humans secreted tissues homeostasis tumorigenesis cascades genes transcriptions IWP-2 IWP2 derivatives benzothiazoles groups parents compounds impairing Wnt/β-catenin β smalls receptors surfaces activations inactivates palmitoylations 8.309447513812
13953 IWP-3 687561-60-0 ≥98% 2013-06-25 10.214419889502 iwp-3 Inhibitor of Wnt Production-3 Wnt signalings cancers embryonic development stems cells β-catenin beta-catenin .beta.-catenin beta catenins inhibitors Porcupines develops IWPs 3 IWP3 IWP-3 in vitro membranes membrane-bound bounds O-acyltransferase palmitoylating proteins blocks blockage blocking LRP6 exo endo inhibits inhibitions disheveled Dvl2 signals transductions intracellular biology productions pathways activity O acyltransferases ability secretions Wnt-dependent dependents phosphorylations LDLs receptor-related 6 related scaffolds Dishevelled preventing accumulations cardiomyocytes generations humans secreted tissues homeostasis tumorigenesis cascades genes transcriptions 10.214419889502
13954 IWP-4 686772-17-8 ≥95% 2013-07-10 11.111215469612 iwp-4 Inhibitor of Wnt Production-4 Wnt signaling cancer embryonic developments stems cells β-catenin b-catenin .beta.-catenin beta-catenin inhibitors Porcupines inhibits inhibitions production impairs pathways in vitro inactivates membranes membrane-bound bounds O-acyltransferase palmitoylating proteins secretion blocks blockage blocking LRP6 Dvl2 dishevelled scaffold LPR-6 LPRs 6 six low-density lipoproteins receptor-related signal transduction intracellular signaling biology 11.111215469612
13659 IWR-1-endo 1127442-82-3 ≥98% 2010-03-23 23.385130228886 iwr-1-endo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expression transcription inhibitors inhibits inhibition proteasomes Apc Axin2 Ck1 Gsk3β IWR-1-exoendo-1,3(4)-beta-D-glucanase Endo-1,3(4)-beta-Glucanase Endo-1,3(4)-B-Glucanase beta-(1-3,1-4)glucanase 23.385130228886
13598 IWR-1-exo 1127442-87-8 ≥98% 2010-03-23 8.866795580110 iwr-1-exo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expressio Cellobiohydrolase, 1,4-beta-D-Glucan 1,4-beta-D-Glucan Cellobiohydrolase 1,4 beta D Glucan Cellobiohydrolase 1,4-beta-Cellobiosidase, Cellulose Cellulose 1,4-beta-Cellobiosidase Cellulose 1,4 beta Cellobiosidase Beta-Glucancellobiohydrolase Beta Glucancellobiohydrolase Exo-Cellobiohydrolase Exo Cellobiohydrolase Cellobiohydrolase II Cellobiohydrolase I Cellobiohydrolase A Cellobiohydrolase Exoglucanase II CEL1 Protein CbhI Proteinn transcription inhibitors inhibits inhibition controls 8.866795580110
11705 Jasplakinolide 102396-24-7 ≥98% 2013-04-15 12.815431067712 jasplakinolide NSC 613009 natural products inhibitors inhibits inhibitions cytoskeletons skeletons macrocyclic peptides marine sponges proliferations proliferates PC3 PC-3 PCs prostate carcinomas cells binds bindings F-actin Factin F actins phalloidin filaments roles motility transports developments jaspamide NSC-613009 NSC613009 in vitro vivo polymerizations monomeric cellular 12.815431067712
15003 JC-1 3520-43-2 ≥98% 2013-03-26 120.813425414365 jc-1 CBIC2; NK 1420 21527-78-6 cells biology NK1420 NK-1420 apoptosis fluorescent probes flows cytometry JC1 JCs 1 mitrochondrial transmembranes cationic dyes iodideindicates indicators J-aggregates aggregates FC ΔΨm CBIC CBIC-2 CBICs NK1420 NK-1420 NKs death cellular membrane-permeable DELTA Phi fluorescence monomers 120.813425414365
10009172 JC-1 Mitochondrial Membrane Potential Assay Kit - 2007-04-12 144.178893412167 jc-1-mitochondrial-membrane-potential-assay-kit apoptosis cells mitochondria caspases cytochrome C electrons transport transmembranes Dym DELTApsim .DELTA..psi.m fluorscence fluorescent cationic dyes rhodamine-123 Rh123 DiOC6 cytofluorimetric lipophilic tetrachloro-1,1',3,3'-tetraethylbenzimidazoylcarbocyanine iodide green red J-aggregates monomeric assays kits measures measurements microscopy flow cytometry plate readers fluorometric cancer JC1 cell-based assays cell based assay cba JC 1 144.178893412167
11511 JNK2 Polyclonal Antibody - 2011-11-18 0E-12 jnk2-polyclonal-antibody MAPK9 antibody; c-Jun N-terminal Kinase 2; p54a; SAPK1a c-Jun kinases JNKs MAP phosphorylation JNK1 JNK3 nuclear signals transduction proteins transcription factors p53 Western blots WB blotting JNKs JNK-1 JNK-2 JNK-3 0E-12
10007542 KAPA (hydrochloride) Exclusive 177408-65-0 ≥98% 2007-07-12 4.970570902394 kapa-hydrochloride 7-keto-8-Aminopelargomic Acid biotins KAPAs DAPAs DTB vitamers growth factors proteins avidins assays intermediates vitamins reporters reactions biosynthetic 7,8-diamino desthiobiotins 4.970570902394
13711 KCNQ1 Potassium Channel Monoclonal Antibody (Clone S37A-10) - 2009-12-02 0E-12 kcnq1-potassium-channel-monoclonal-antibody-clone-s37a-10 antibodies western blots WB immunoblotting blotting immunoprecipitation IP immunohistochemistry IHC KCNQ-1 IKs inner ears cardiac muscles channels Kv7.1 hyperpolarization-activated cation hyperpolarization activated activity activate 0E-12
13713 KCNQ4 Potassium Channel Monoclonal Antibody (Clone S43-6) - 2009-12-02 0E-12 kcnq4-potassium-channel-monoclonal-antibody-clone-s43-6 antibodies western blots blotting immunoblotting immunoprecipitation immunocytochemistry ICC IP KCNQ-4 proteins retigabine hyperpolarization-activated hyperpolarization activated activity activate cation antioconvuslants anti-convulsantd 0E-12
10009437 Kifunensine 109944-15-2 ≥98% 2007-04-30 248.773729281768 kifunensine FR 900494 inhibitors cells biology glycoproteins glycosidases mannosidases kitasatosporia kifunense inhibition inhibits blocks a-mannosidase a-mannosidase alpha-mannosidase .alpha.-mannosidase endoplasmic reticulum ERs mutated mutations proteins golgi family subfamily 1A 1B 1C biosynthesis 248.773729281768
13714 Kir2.1 Potassium Channel Monoclonal Antibody (Clone S21-32) - 2009-12-02 0E-12 kir2-1-potassium-channel-monoclonal-antibody-clone-s21-32 channels antibodies western blots blotting immunoblotting WB immunohistochemistry IHC KCNJ2 genes Andersen-Tawil syndromes Andersen Tawil AT defects 0E-12
13715 Kir2.2 Potassium Channel Monoclonal Antibody (Clone S24-1) - 2009-12-02 0E-12 kir2-2-potassium-channel-monoclonal-antibody-clone-s24-1 channels ions antibodies western blots blotting immunoblotting WB immunohistochemistry IHC syndromes Smith-Magenis Smith Magenis chromosomes 17 seventeen tissues genes 0E-12
13716 Kir2.3 Potassium Channel Monoclonal Antibody (Clone S25-35) - 2009-12-04 0E-12 kir2-3-potassium-channel-monoclonal-antibody-clone-s25-35 antibodies channels ions western blots blotting immunoblotting WB IHC immunohistochemistry genes proteins potassiums 0E-12
14046 KLH Polyclonal Antibody - 2013-01-15 1.946850828729 klh-polyclonal-antibody Keyhole Limpet Hemocyanin negative control primary antibody KLH mammalian lysate 1.946850828729
13318 KN-62 127191-97-3 ≥98% 2009-07-16 7.515317679557 kn-62 inhibitors calcium calmodulin-dependent kinase II CaM kinase II purinergic receptors P2RX7 P2X7 inhibition inhibited selective permeableCaMKII calcium ca modulation CaMK11CaMK2 7.515317679557
9000890 KN-92 (hydrochloride) Exclusive 1431698-47-3 ≥98% 2011-05-25 10.125511049723 kn-92-hydrochloride Ca2+/calmodulin-dependents kinases II CaMKII KN-93 controls cells cycles inhibitors inhibited inhibition NIH 3T3 13319 inhibits KN92 KN 92 KN93 KN 93 176708-42-2 10.125511049723
13319 KN-93 139298-40-1 ≥98% 2009-08-05 17.318817679557 kn-93 inhibitors inhibits inhibition Ca2+ calmodulin dependent Ca2+/calmodulin-dependent kinase II CaMKII histamine parietal cells cardiac myocytes 5-LO 5-lipoxygenase HIF-1a HIF-1α HIF1α colon cancers phosphorylation CAM 17.318817679557
13864 KN-93 (hydrochloride) Exclusive - ≥98% 2013-03-14 10.676906077347 kn-93-hydrochloride 139298-40-1 inhibitors cells biology signals transductions KN93 KNs 93 inhibits inhibitions CaMKII Ca2+ calmodulin dependent kinases II blocks blocking histamines aminopyrine uptake up-take cancers calmodulin-dependent Ca2+-phosphodiesterases calcium- histame-induced parietal Ca2+-induced calcium-induced cardiac hearts myocytes constitutive phosphorylations 5-lipoxygenases 5-LO Ca2+-dependent calcium-dependent activations HIF-1α HIF-1 alpha HIF-1.alpha. HIF-1a colons 10.676906077347
10010965 KT 5823 126643-37-6 ≥95% 2009-01-15 104.672697974217 kt-5823 cGMP PKGs proteins kinases G inhibitors inhibits inhibition nitric oxides NO antibiotic KT5823 KT-5823 indolocarbazoles alkaloid PKG 104.672697974217
13717 Kv3.1b Potassium Channel Monoclonal Antibody (Clone S16B-8) - 2009-12-04 0E-12 kv3-1b-potassium-channel-monoclonal-antibody-clone-s16b-8 antibodies ions channels Shaw subfamily subfamilies western blots blotting immunoblotting WB immunohistochemistry IHC oxygen sensors olivocochlear effernet systems proteins potassiums voltage-gated show-related subfamily 0E-12
14775 L3MBTL1 MBT domains (human recombinant; GST-tagged) - ≥90% 2013-10-09 1.987130920019 l3mbtl1-mbt-domains-human-recombinant-gst-tagged L(3)MBT-like; H-l(3)MBT; Lethal(3)Malignant Brain Tumor-like Protein 1 expressions genes histones chromatin epigenetics MBTs domains cancers silencing cells cycles developments malignant brains tumors PWWP polycomb groups PcGs transcriptional transcriptions repressors repeats H3 H4 binds bindings binders mono dimethylated lysines H3K4me1 H4K20me2 compaction tumors suppressors genomic stability DNA replications repeats regions methyl readers regulations damages repairs demethylase chromatin biology histones H-l(3)mbt proteins L(3)mbt homolog L(3)MBTL1 1.987130920019
10011444 LAMP2 Monoclonal Antibody (Clone GL2A7) - 2008-06-02 0E-12 lamp2-monoclonal-antibody-clone-gl2a7 Lysosome Associated Membrane Protein 2 ICC immunocytochemistry lysosomes endosomes cells LAMP-2 immunoprecipitation IP 0E-12
10010630 Latrunculin A 76343-93-6 ≥98% 2008-07-02 23.507145488030 latrunculin-a NSC 613011 thiazolidinone macrolides monomeric actins G-actin Gactin F-actin Factin cytoskeleton dexamethasone 23.507145488030
10010631 Latrunculin B 76343-94-7 ≥97% 2009-02-20 17.923756906078 latrunculin-b monomeric actins G-actin G actins F-actin F inhibitors inhibits inhibition cytoskeleton 17.923756906078
10008882 LDH Cytotoxicity Assay Kit - 2006-12-15 170.318867581249 ldh-cytotoxicity-assay-kit Lactate Dehydrogenase Cytotoxicity Assay Kit cells death apoptosis necrosis measuring measurement cystolic enzymes cells membranes integrity cancer cell-based assays cell based assay cba 170.318867581249
14415 LE 135 155877-83-1 ≥98% 2013-06-25 1.386740331492 le-135 retinoic acids receptors RARs antagonists RARβ transcriptions activations inhibitors inhibits inhibitions LE135 LE-135 Les 135 RARb RAR-b b RAR.beta. RAR-.beta. .beta. RARbeta RAR-beta beta RAR-β β acid-induced induces transcriptional RXRs RXRa RXR-a RXRalpha RXR-alpha RXR.alpha. RXR-.alpha. RXRα α retinoids am80 am-80 ams 80 80-induced humans leukemia HL-60 HL60 HLs 60 cells promyelocytic nuclears receptors biology cancers moderate selectivity RARγ RARgamma RAR.gamma. RAR-gamma RARg RAR-g g X alpha beta gamma γ differentiations 1.386740331492
10008426 L-myo-Inositol-1,4,5-triphosphate (sodium salt) 2068-89-5 ≥98% 2009-09-14 7.374046961325 l-myo-inositol-1-4-5-triphosphate-sodium-salt D-myo-Inositol-3,5,6-triphosphate (sodium salt); Ins(1,4,5)P3 (sodium salt); 1,4,5-IP3 (sodium salt) inositols phosphates calcium cells signaling isomers D-myo-inositol-1,4,5-triphosphate 2068-89-5 7.374046961325
10006984 LPA1 Blocking Peptide - 2006-03-16 9.613370165746 lpa1-blocking-peptide EDG-2; LPA Receptor 1; LPAR1; Vzg-1 proteins diseases antibodies antisera antiserum WB western blots blotting ICC immunocytochemistry analogs GPCRs controls 9.613370165746
10005280 LPA1 Polyclonal Antibody - 2005-04-05 23.583100061387 lpa1-polyclonal-antibody LPA Receptor 1; LPAR1; Vzg-1; EDG-2 LPA analogs antibodies antisera antiserum western blots blotting wb icc immunocytochemistry GPCRs immunoblotting 23.583100061387
10005092 LPA3 Blocking Peptide - 2004-05-11 61.008821362799 lpa3-blocking-peptide EDG-7; Lysophosphatidic Acid Receptor 3 LPA analogs antibodies western blots blotting wb icc immunocytochemistry control peptides 61.008821362799
10004840 LPA3 Polyclonal Antibody - 2004-05-11 30.389676400947 lpa3-polyclonal-antibody Lysophosphatidic Acid Receptor 3; EDG-7 analogs antibodies antisera antiserum western blots blotting wb icc immunocytochemistry GPCRs edg7 receptors g-proteins coupled s1p1-5 cellular responses, cytoskeletal rearrangements proliferation inhibits inhibitors inhibition gap junction communication immunoblotting ELISA 30.389676400947
600310 Lysosome/Cytotoxicity Dual Staining Kit - 2010-06-15 28.333378058406 lysosome-cytotoxicity-dual-staining-kit lysosomes membrane-bound acidic intracellular compartments cells waste products fats carbohydrates proteins macromolecules mobilize recycle organelles microorganisms animals leukocytes degradative enzymes hydrolases pH 5 cytoplasm homeostasis Tay-Sachs diseases arthritis neurodegeneratives Parkinson's brains cathepsin D genes therapeutics kits assays measures measurements 4-Nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole NBD-PZ membranes permeable carboxylic acids luminal cultured propidium iodides death chloroquine inhibitors positive controls fluorescence fluorescent microscopy plates reader detections flow cytometry 28.333378058406
600160 Methionine Sulfoxide Immunoblotting Kit - 2009-12-17 192.514895027624 methionine-sulfoxide-immunoblotting-kit MetO Immunoblotting Kit proteins sulfoxides oxidative modifications residues MSRs reactive oxygen species ROSs methionines oxidations reductases sulfones phagocytosis phagocytotic mitochondrias mitochondrial respirations sulfoxidations age-related diseases cellular cells IgG-containing sera Alzheimer's diseases immunoblots immunoblotting western blots blotting kits assays measures measurements detection tissues lysates semi-pure purified reducing non-reducing sample buffers SDS-PAGE rabbit serums immunizations oxidized corn MetO-DZS18 192.514895027624
13357 Milrinone 78415-72-2 ≥98% 2011-03-07 196.953093922651 milrinone WIN 47,203; Primacor® inhibitors phosphodiesterases PDE3A PDE3B cAMP vascular diseases cardiovascular effects Sanofi Synthelabo Brand of Milrinone Lactate Sanofi Winthrop Brand of Milrinone Lactate Sanofi Synthelabo Brand of Milrinone Sanofi Brand of Milrinone Lactate Lactate Milrinone Milrinone Lactate Win-47203 Win 47203 Milrinone Corotrope Win47203 Primacor Corotrop inhibits inhibition 196.953093922651
15217 MLN 4924 New 905579-51-3 ≥98% 2013-11-13 47.555555555555 mln-4924 Pevonedistat neddylation NEDD8 ubiquitin-like proteins cullin-RING E3 ligases CRLs ubiquitination cancers inhibitors inhibits inhibitions NEDD8-activating enzymes NAE anti-tumor bortezomib therapy therapies NEDD-8 NEDDs 8 eight ubiquitin like cullin RINGs activating active activity antitumors anti tumors MLN4924 MLN-4924 analogs adenosine 5 monophosphate UAE SUMO SAE HCT-116 HCT116 DNA S-phase s phase in vivo E 3 proteasome-dependent proteasomes dependents turnovers substrates cellular processes cells survival targets therapeutic research MLN 4924 5’-monophosphate 5’ CRL-mediated mediated apoptosis HCT 116 deregulating synthesis dose-dependently doses dependently suppresses growth humans xenografts mice 47.555555555555
15269 MLS-573151 New 10179-57-4 ≥98% 2013-12-06 46.666666666667 mls-573151 inhibitors inhibits inhibitions signals transductions cancers cells cycling intracellulars signalings biology cytoskeletal research MLS000573151 MLSs 573151 MLS573151 MLS-000573151 000573151 Cdc42 division control protein s42 homologs specific 46.666666666667
10009365 MTT Cell Proliferation Assay Kit - 2007-02-15 72.520387150949 mtt-cell-proliferation-assay-kit assays kits screen measures measurements cells cellular growth factors signaling signalling molecules transcription DNA pathological cancers aging cycles progression regulatory cytokines mitogens drugs inductions inhibitors inhibits inhibitions in vitro plasma membranes formazan intracellular NAD(P)H-oxidoreductases NADPH-oxidoreductases proteins enzymes enzymatic cleavage microtiter plates tertrazolium salts mitochondrial dehydrogenases cancer cell-based assay cell based assay cba 72.520387150949
600330 Multi-Parameter Apoptosis Assay Kit - 2010-08-18 56.735335481891 multi-parameter-apoptosis-assay-kit assays kits measures measurements apoptosis cells death cycles tissues homeostasis dysregulation neurodegenerative diseases ischemic damages autoimmune disorders cancers drugs discovery signaling pathways membranes phospholipids phosphatidylserines phosphatidylethanolamines leaflets bilayers externalizations residues plasma phospholipids binding proteins fluorochrome-labeled fluorochromes annexin V fluorescence microscopy flow cytometry FC plate readers TUNEL TdT-mediated dUTP Nick-End Labeling analysis ISEL in situ end labeling DNA deoxyribonucleic acids mitochondrial transmembranes tetramethylrhodamines ethyls esters TMRE lipophilics probes laddering detection fragmentation FITC-conjugated fluoresceins 56.735335481891
14219 Multiubiquitin Chain Monoclonal Antibody (Clone FK1) - 2013-08-01 14.499465999776 multiubiquitin-chain-monoclonal-antibody-clone-fk1 ubiquitin eukaryotic cells post-translational modifications substrates ubiquitination apoptosis cycles division DNA transcription immune responses modulations surfaces receptors viral infections viruses polyubiquinated conjugates free monoubiquitinated ELISA IHC immunohistochemistry western blots blotting WB mouse immunoblotting 14.499465999776
14220 Multiubiquitin Chain Monoclonal Antibody (Clone FK2) - 2013-08-01 21.648455898767 multiubiquitin-chain-monoclonal-antibody-clone-fk2 ubiquitin eukaryotic cells post-translational modifications substrates ubiquitination apoptosis cycles division DNA transcription immune responses modulations surfaces receptors viral infections viruses polyubiquinated conjugates free monoubiquitinated ELISA IHC immunohistochemistry western blots blotting WB mouse immunoblotting 21.648455898767
13351 Myristic Acid 544-63-8 ≥98% 2009-08-11 4.861712707182 myristic-acid Tetradecanoic acid; NSC 5028 fatty acids N-myristoylation 45184-05-2 14-carbon saturated 14:0 1-Tridecanecarboxylic acid Edenor C 14 Emery 655 Hystren 9014 Imex C 1499 Lunac MY 98 NAA 104 NAA 142 Neo-Fat 14 Palmac 98-14 Philacid 1400 Prifac 2942 Prifrac 2942 Univol U 316S n-Tetradecan-1-oic acid n-Tetradecoic acid MY-98 MY98 NAAs NAA-104 NAA-142 NAA104 NAA142 NSCs 5028 NSC-5028 NSC5028 4.861712707182
13055 Naphthofluorescein 61419-02-1 ≥98% 2009-03-20 5.114235955363 naphthofluorescein CCG 8295 furin matrix metalloproteinase MTA-MMP MMP2 motility invasion cancer metastasis MMP inhibitors naphthafluorescein 5.114235955363
13718 Nav1.7 Sodium Channel Monoclonal Antibody (Clone S68-6) - 2009-12-04 0E-12 nav1-7-sodium-channel-monoclonal-antibody-clone-s68-6 antibodies channels ions western blots blotting immunoblotting immunoprecipitation WB IP immunocytochemistry ICC pain sensitivity insensitivity sodiums voltage-gated voltage gated 0E-12
11658 Necrostatin-1 4311-88-0 ≥98% 2012-06-06 9.755000000000 necrostatin-1 Nec-1 143443-40-7 Nec1 Nec 1 necroptosis necrosis cells death RIP1 TNFα RIP1 kinases inhibitors ischemic brain injury myocardial infarction TNF-α TNF α inhibits inhibition FADD Jurkat RIP-1 RIP 1 9.755000000000
10527 Necrostatin-5 337349-54-9 ≥98% 2012-04-02 3.315893186003 necrostatin-5 Nec-5 necroptosis necrosis cells death RIP1 TNFα RIP1 kinases inhibitors inhibits inhibition necrostatin 5 caspase Fas ligands serine threonine receptors tumors TNFα TNF-α FADD jurkat serine/threonine Ser/Thr 3.315893186003
10528 Necrostatin-7 351062-08-3 ≥98% 2012-03-13 3.510644567219 necrostatin-7 Nec-7 necroptosis necrosis cells death TNFα TNF-α inhibitors inhibits inhibition RIP1 Fas ligands tumors kinases Nec7 Nec 7 3.510644567219
14287 Neomycin (sulfate) 1405-10-3 ≥90% 2013-04-24 63.888438714957 neomycin-sulfate antibiotics proteins synthesis inhibitors aminoglycosides antibacterial cells cultures calcium channels Streptomyces fradiae S. inhibits inhibitions tissues translation binds bindings prokaryotic ribosomes skeletal muscles sarcoplasmic reticulum Ca2+ inositols phospholipids C D biosol bykomycin endomixin fradiomycin sulfates lidamycin crème myacine mycerin mycifradin N mycifradin-N myciguent neo-mantle neo mantle neobrettin neofracin neolate neomix sulphate neosulf new france F france-f nivemycin otobiotic quintess-N quintess tuttomycine 1339-25-9 8013-33-0 8057-38-3 12710-33-7 37318-28-8 56571-68-7 57866-39-4 60799-77-1 63626-34-6 124847-89-8 125863-87-8 126663-40-9 126683-25-8 127085-47-6 ions SR small subunits voltages voltage-sensitive sensitive voltage-gated gated turnovers phospholipases C PLCs phosphatidylcholines phosphatidylcholine-phospholipase Gram-positives Gram positives Gram-negatives negatives contaminations 63.888438714957
600610 Neutrophil Elastase Activity Assay Kit - 2012-06-21 80.843356353591 neutrophil-elastase-activity-assay-kit kits assays measures measurement neutrophils elastases enzymes leukocytes humans blood cytoplasmic cytoplasms azurophilic granules cells cellular stimulation pathogens phorbol myristate acetate PMA excreted excretion exocytosed exocytosis proteins networks of extracellular traps NET proteases released degrades degrading invading immune immunity systems responses expression non-small lung cancers tumors lines U937 HL-60 invasion metastasis insoluble elastins matrix mutations ELA2 genes encoding hereditary neutrophenia inflammatory chronic diseases therapeutics non-fluorescent substrates (Z-Ala-Ala-Ala-Ala)2Rh110 R110 whole regulates regulating releases 80.843356353591
600620 Neutrophil Myeloperoxidase Activity Assay Kit - 2012-08-28 107.560218226154 neutrophil-myeloperoxidase-activity-assay-kit Neutrophil MPO kits assays measures measurement MPOs myeloperoxidases peroxidases enzymes neutrophils leukocytes humans blood active cytoplasmic cytoplasms azurophilics granules cells activations stimulations stimulates activates pathogens pharmacological agents phorbal myristates acetates PMA phagolysosomes excreted extracellular regions proteins networks of traps NETs degrades degrading invading earliest early line defenses innate immunity systems catalyzes hydrogen peroxides peroxide-mediated oxidation halides ions hypochlorous acids HOCl reactives products secondary reactions rxns modifications destruction matrix matrices bacterial bacteria killing kills diseases cystic fibrosis renal dysfunctions arthritis cancers immunoresponses therapeutics 3,3’,5,5’-tetramethyl-benzidine TMB chromogenic substrates isolates whole samples 4-aminobenzhydrazide ABH 107.560218226154
11437 Nigericin (sodium salt) 28643-80-3 ≥98% 2012-04-30 13.587016574586 nigericin-sodium-salt NSC 292567 28380-24-7 antibiotic, potassium ionophore K+/H+ exchange, mitochondria membranes potential Streptomyces hygroscopicus cells pH T. gondii parasites efflux 13.587016574586
11214 NKH477 (hydrochloride) 138605-00-2 ≥95% 2012-02-16 54.079834254144 nkh477-hydrochloride Adehl; Colforsin Dapropate 113462-26-3 adenylate cyclase adenylyl cAMP cyclic AMP vascular diseases cardiovascular cardiac hypotension hypertension analogs cardiac smooth muscles histamines forskolin 11018 HCl hydrochloride NKH-477 NKH 477 54.079834254144
13857 Nocodazole 31430-18-9 ≥98% 2013-01-11 7.333038674033 nocodazole NSC 238159; R 17934; Oncodazole 59697-13-1 NSC238159 NSC-238159 R17934 R-17934 microtubules cytoskeleton cells cycling mitosis cancera division synchronization binds binding tubulin GTP hydrolysis elongation shortening velocities G2/M phase Golgi ministacks eukaryotic 7.333038674033
10007190 Nodularin 118399-22-7 >95% 2006-03-30 9.192150519205 nodularin cyanobacterium Nodularia spumigena contaminates contamination drinking water rural communities mussels flounder cod Northern Baltic Sea heptotoxic monocyclics pentapeptides inhibitors inhibition inhibits proteins proteases types 1 2A PP1 2A 2B 2C alkaline phosphatases acids insulin receptors tyrosine kinases phosphorylases 9.192150519205
600590 Nrf2 Transcription Factor Assay Kit - 2013-07-17 35.799009774755 nrf2-transcription-factor-assay-kit HEBP1; Nuclear Factor Erythroid 2-related factor 2; NF-E2-related factor 2; Nuclear factor E2-related factor 2; GABPA assays kits measuring measurement TFs factors NF-E2-related 2 Nuclear (erythroid-derived 2)-like 2 NFE2L2 E2 related leucines zippers types zipper-types transcriptions ubiquitously expressed expressions kidneys muscles lungs livers redox homeostasis oxidations reductions interactions cysteines cysteine-rich proteins Kelch like Kelch-like ECH-associated ECH associated 1 Keap1 resting cells complexes targets targeted targeting degrades degradations proteasomes oxidatives stresses undergoes conformational changes phosphoryateds phosphorylations releases releasing Nrf2/Keap1 translocations nucleus nuclei induced inductions genes encodes encoding cytoprotections cytoprotectives antioxidatives antioxidants enzymes activates activations defenses systems cellular molecules molecular damages cancers developments diseases diabetes neurodegenerative neurodegenerations diets dietary factors curcumin downstream lowers lowering inflammations inhibitors inhibits inhibitions carcinogenesis protections xenobiotics drugs interventions disorders nonradioactives non-radioactives non radioactives methods specifics DNA deoxyribonucleic acids binds bindings activity activities nuclear extracts double stranded dsDNA response elements primary antibody antibodies secondary 1 2 HRP horseradish peroxidases colorimetric ELISA EMSA enzyme-linked immunosorbents assays immunoassays radioactives electrophoretics mobility shift 35.799009774755
13196 NSC 23766 (hydrochloride) 1177865-17-6 ≥98% 2010-07-20 23.749889502762 nsc-23766-hydrochloride 733767-34-5 GTPases cells cycles growth proliferations cell-cell adhesions motility differentiation guanine nucleotides exchange factors GEFs inhibitors inhibits inhibition cell migration Aminoquinolines angiogenesis leukemia cancers gene expression Rac1 Inhibitor 23.749889502762
10010299 Oleoyl 3-carbacyclic Phosphatidic Acid Exclusive 779333-58-3 ≥95% 2009-10-14 18.184978514425 oleoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 18:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA oleate transcellular migration MM1 cells mesothelial autotoxin cancer survival growth migration invasion metastasis antagonist LPA1 LPA2 LPA3 476310-24-4 18.184978514425
11342 Oligomycin A 579-13-5 ≥98% 2012-03-05 7.337651933702 oligomycin-a MCH 32 11030-76-5 21307-25-5 31422-20-5 macrolide isomers mitochondria F1F0-ATP synthases apoptosis antifungals antitumors nematocidal Streptomyces toxic metabolism analogs MCH-32 MCH32 7.337651933702
11343 Oligomycin B 11050-94-5 ≥95% 2012-03-05 4.618591160221 oligomycin-b macrolide isomers mitochondria inhibitors ATP synthase inhibits inhibitions toxic mitochondrial metabolism myocardial ischemia Streptomyces toxic calcium rats neurons 4.618591160221
11341 Oligomycin Complex 1404-19-9 ≥98% (Mixture of A, B, C) 2012-07-24 5.228508287293 oligomycin-complex 11098-49-0 ATPs ATP synthases oligomycin A B ischemia inhibitors apoptosis inhibits inhibitions oligomycins mitochondrial F1-F0 F1F0 F1 F0 5.228508287293
600250 Orexin 2 Receptor STEP Reporter Assay Kit (Luminescence) Exclusive - 2010-03-31 3.239377197388 orexin-2-receptor-step-reporter-assay-kit-luminescence OX2R hypercretins 1 orexins 2 systems regulates regulator sleep wake cycles feeding cardiovascular autonomic ANS hypothalamic neuropeptides A B gut hormones secretions hypothalamus midbrains brainstems G protein-coupled receptors GPCRs orexin-1 OX1R orexin-2 OX2R orexin-A orexin-B sleep disorders narcolepsy humans animals rodents energy homeostasis pain stress antagonists drugs addictions withdrawals therapeutics obesity Surface transfections and expressions protocols solid phase transient transfection technology originus patents USPT US6897067 US6902933 US7056741 US 6897067 6902933 7056741 DNA deoxyribonucleases adherent cells receptor-mediated luminescent secretory alkaline phosphatases SEAP signals transductions cascades culture medium luminescence-based high throughput HTS screening screens agonists 3.239377197388
601060 Oxygen Consumption/Glycolysis Dual Assay Kit New - 2014-02-27 0E-12 oxygen-consumption-glycolysis-dual-assay-kit kits assays measures measuring measurement Warburg effect mitochondrias mitochondrion eukaryotes eukaryotic cells organelles energy energies ATP adenosines triphosphates generation cellular physiological signals signaling growths differentiations deaths necrosis dysfunctions diseases strokes Alzheimer's metabolic paths pathways changes pathological developments cancers aerobic glycolysis oxygens O2 oxidatives phosphorylations roles pharmacologicals targets functions therapeutics targets single parameter mechanisms drugs multi-parameter multiparameter consumptions glycolysis metabolics responses treatments electrodes phosphorescent probes MitoXpress Xtra MitoXpress-Xtra MitoXpress - Xtra MitoXpress® Xtra MitoXpress®-Xtra MitoXpress® - Xtra signals Luxcel Biosciences whole rates lactates extracellular levels intracellular glycolytic activity activities cultured media mediums dehydrogenases catalyzes catalyzing pyruvates NADH nicotinamides adenines dinucleotides reduced reduces tetrazolium substrates INT formazan derivatives simultaneously live living antimycin A inhibits inhibitors inhibitions mitochondrial ETC electrons transports chains controls HTS high throughputs screens screenings modulates apoptosis 0E-12
600800 Oxygen Consumption Rate Assay Kit (MitoXpress®-Xtra HS Method) - 2013-03-14 105.949734329172 oxygen-consumption-rate-assay-kit-mitoxpress-xtra-hs-method OCR kits assays measures measurements CBAs cell-based cells cellular respirations energy growths repairs movements enzyme enzymatic precesses processing aerobic indicators normal functions unhealthy dysfunctional mitochondrias cancers glycolysis Warburg effects parameters oxidatives phosphorylations electrodes phosphorescents probes Luxcel biosciences whole phosphorescence signals signalling signaling high senstivity Extra MitoExpress living antimycin A oxidations ETCs electrons transports chains positive controls glucose oxidases references depletions HTS high-throughput screens screenings modulates rates OCRs 105.949734329172
15224 P005091 New 882257-11-6 ≥98% 2013-11-12 40.513373721278 p005091 ubiquitin-specific ubiquitins specifics proteases USPs UBPs ubiquitylation proteasome USP7 cysteines USP-7 7 seven prostate cancers deubiquitylation HDM2 HDMs HDM-2 2 two E3 ligase tumors suppressors p53 anticancer anti-cancer anti multiple myeloma bortezomib therapy therapies deubiquintinase DUB selective USP/UBP P-005091 Ps 005091 P-5091 P5091 5091 trisubtituted thiophene inhibits inhibitions inhibitors caspases cathepsins calpain metalloproteases serines myeloma doxorubicin etoposide mechlorethamine in vivos B B-cells Bcells leukemia growths intracellular signaling P5091 40.513373721278
10011301 p38 MAPK Monoclonal Antibody (Clone 9F12) - 2008-05-22 1.169337016574 p38-mapk-monoclonal-antibody-clone-9f12 p38 MAPKα; p38 Mitogen-activated Protein Kinase serine threonine serine-threonine cell cycles development apotosis kinases stress signals cytokines gene expression western blots immunoblotting immunocytochemisty ICC WB flow cytometry signal transduction signalling signaling blotting FC 1.169337016574
10010374 p38 MAPK (Phospho-Thr180/Tyr182) Cell-Based Phosphorylation/Translocation Assay Kit - 2007-09-17 0.515138121547 p38-mapk-phospho-thr180-tyr182-cell-based-phosphorylation-translocation-assay-kit phosphorylation kits assays enzymes diseases asthma autoimmunity stress response nervous system fluorescence fluorescent fluorometric 0.515138121547
600060 p53 Total and p53 (Phospho-Ser392) Dual Staining Assay Kit - 2009-03-10 1.409852670350 p53-total-and-p53-phospho-ser392-dual-staining-assay-kit kits assays measuring measurements tumors treatments DyLightTM (-)-Nutlin-3 positive ontrols p53(Phospho-Ser392) dsDNA double-stranded suppressors proteins guardians of the genomes cells cellular responses genotoxic stresses activity cycles arrests apoptosis senescence cancers mutations inactivated binding ubiquitination acetylation phosphorylation sumoylation neddylation methylation glycosylation damages oncogenes ribosomal cell-matrix matrices adhesion hypoxia p21 WAF1 Cip1 MDM2 GADD45 Cyclin G Bax IGF-BP3 bcl-2 Bcl-XL cyclins B1 MAP4 survivin HPV16 PARP-1 WT1 E1b/E4 degradation nucleus cytoplasms proteasomes promoter carcinogenesis endogenous autosomal Li Fraumeni Syndromes nuclear extracts cell-based assays cell based assay cba 1.409852670350
10007358 Palmitic Acid methyl ester 112-39-0 >99% 2006-02-17 13.623747851955 palmitic-acid-methyl-ester Methyl Palmitate; MP esters saturated fatty acids synthesized synthesis plants animals acetyl coenzymes CoA energy storage 16-carbon dietary fats plasma lipoproteins expression COX-2 cyclooxygenase-2 cyclooxygenases proteins acylation lipids anchoring signaling signalling molecules 13.623747851955
10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid Exclusive 910228-13-6 ≥95% 2009-11-03 8.147920284135 palmitoleoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 16:1; 3-carbacyclic PA cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitoleate transcellular migration MM1 cells mesothelial autotoxins cancer survival growth migration invasion metastasis NPP2 ENPP2 ectonucleotide pyro phosphatase/phosphodiesterase 2 8.147920284135
10010293 Palmitoyl 3-carbacyclic Phosphatidic Acid Exclusive 476310-22-2 ≥95% 2009-10-07 11.773950276242 palmitoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 16:0 cyclic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitate transcellular migration MM1 cells mesothelial autotoxins cancers survival growth migration invasion metastasis 11.773950276242
10524 Paprotrain 57046-73-8 ≥98% 2013-02-04 0E-12 paprotrain Passenger Proteins Transport Inhibitor mitotic kinesin-like protein 2 MKLP-2 MKLP2 MKLPs 2 kinesin-6 cytokinesis chromosomes passengers proteins Aurora B kinases Survivin centromeres mitotic spindle mitosis anaphase binucleated cells Passenger PROteins TRAnsport Inhibitors microtubule kinesins inhibits inhibitions ATP ATPase MPP1 MPP-1 MPPs polymerization biology cancers 0E-12
11345 Paxilline 57186-25-1 ≥98% 2012-03-01 1.691104972376 paxilline (+)-Paxilline Paxicillin Paxillin inhibitors inhibits inhibitions channels K+ blockers potassium BKCa cells signaling smooth muscle vascular cardiovascular neuronal neuroscience 1.691104972376
10994 Paxillin (Phospho-Tyr118) Polyclonal Antibody - 2012-01-13 0E-12 paxillin-phospho-tyr118-polyclonal-antibody proteins LIM domains ERK-regulated scaffolds vinculin-binding phosphorylation Western blots blotting WB ERKs binds binding vinculin JNK 0E-12
10004805 PCNA Monoclonal Antibody (Clone IPO-38) - 2004-08-27 1.633281767955 pcna-monoclonal-antibody-clone-ipo-38 Proliferating Cell Nuclear Antigen; Nuclear Antigen of Proliferating Cells WB western blots blotting IHC immunohistochemistry immunoblots proliferating cells nuclear antigens ipo38 flow cytometry immunocytochemistry ICC mitosis DNA polymerases holoenzymes antibodies antisera antiserum cancers immunoblotting FC 1.633281767955
10240 PCSK9 Polyclonal Antibody - 2009-07-21 16.305313075506 pcsk9-polyclonal-antibody Proprotein Convertase Subtilisin Kexin 9; NARC-1 PCSK-9 PCSK 9 western blots ICC WB immunocytochemistry protease LDLs lipoproteins low-density low density cholesterol immunoblotting blotting 16.305313075506
13032 PD 173074 219580-11-7 ≥98% 2009-07-29 29.909041129527 pd-173074 fibroblast growths factors receptors FGFRs FGFR1 tyrosine kinase activity activities activation signals propagation inhibitors inhibition inhibits autophosphorylation PDGFR c-Src cSrc c Src EGFR InsR MEK PKC FGFR2 FGFR3 FGFR4 FGFR5 angiogenesis cancers tumors self-renewal self renewal stems cells ERK1/2 ERK-1/2 ERK 1/2 PD173074 29.909041129527
11347 Penitrem A 12627-35-9 ≥98% 2012-03-05 28.784223449969 penitrem-a NSC 354845; Tremortin A 12679-82-2 inhibitors inhibits inhibition channels blockers potassium BKCa cells signaling smooth muscles vascular cardiovascular neuronal neuroscience SLO1 Maxi-K fungal fungus toxins 28.784223449969
600990 Perfecta3D® Cell Viability Kit Exclusive New - 2013-10-24 54.955693490272 perfecta3d-cell-viability-kit cells cell-based based assay kits measuring measurements proliferations controlled controlling controls GFs growths factors binds bindings receptors surfaces connects intracellular signaling molecules actives TFs transcriptions DNA deoxyribonucleic acids proteins productions divisions dysfunctions regulatory cascades abnormal humans pathologicals conditions cancers aging mechanisms alters alterations cycles progressions diseases regulatory cytokines mitogens drugs 2 two dimensional 2D 3 three 3D cultures plates monolayer colorimetric substrates WST-1 environments normal body bodies hanging drops Biomatrix forms forming spheroids plastics grown grows growths tests compounds weeks enzymes enzymatic cleavages tetrazolium salt formazan cellular mitochondrial mitochondrias dehydrogenases viable screens regulations 54.955693490272
601050 Perfecta3D® LDH Cytotoxicity Assay Kit Exclusive New - 2014-02-27 0E-12 perfecta3d-ldh-cytotoxicity-assay-kit Perfecta3D® Lactate Dehydrogenase Cytotoxicity Assay Kit kits assays cells based cell-based measures measuring measurements deaths necrosis apoptosis membranes damaged damages leaky permeability permeabilities viability viabilities lactates dehydrogenases LDHs solubles enzymes cytoplasms lysis activity activities cultures mediums media integrity markers two dimensional 2D 2 D 2-D 3D 3 D 3-D normal body bodies hanging drops Biomatrix spheroids models plates coupled reactions rxns two-step steps catalyzes catalyzing reductions nicotinamides adenines dinucleotides reduced oxidations pyruvates diaphorases reduces tetrazolium salts INT formazan derivatives 0E-12
600540 Phagocytosis Assay Kit (IgG PE) - 2012-01-10 82.349364640884 phagocytosis-assay-kit-igg-pe kits assays measuring measurement ingestion killing phagocytic leukocytes defense pathogens microbe-innate immune cytoskeletal rearrangement membrane trafficking microbial mechanisms pro-inflammatory anti-inflammatory cytokines chemokines apoptosis antigen immune systems pathological Multiple Sclerosis Alzheimer's diseases atherosclerosis bacterial fungal infections in vitro fluorescently opsonizing latex beads fluorescently-labeled flow cytometry cytometric analysis quantification cell-based cell based cba phycoerythrins probes fluorescence 82.349364640884
10007191 PH Domain Leucine-rich Repeat Protein Phosphatase 1 Polyclonal Antibody - 2006-01-04 6.484005524861 ph-domain-leucine-rich-repeat-protein-phosphatase-1-polyclonal-antibody KIAA0606 Protein; PHLPP1; PLEKHE1 Protein; SCOP; Suprachiasmatic Nucleus Circadian Oscillatory Protein proteins diseases antibodies antisera antiserum western blots blotting immunocytochemistry ICC immunohistochemistry IHC cancers WB immunoblotting PH Domain Leucine-rich Repeat Protein Phosphatase Polyclonal Antibody 6.484005524861
10007192 PH Domain Leucine-rich Repeat Protein Phosphatase Blocking Peptide - 2006-01-30 2.594488950276 ph-domain-leucine-rich-repeat-protein-phosphatase-blocking-peptide KIAA0606 Protein; PHLPP; PLEKHE1 Protein; SCOP; Suprachiasmatic Nucleus Circadian Oscillatory Protein western blotting blots signaling signalling WB IHC ICC immunohistochemistry formalin-fixed paraffin-embedded immunocytochemistry proteins kinases Akt cells growth death serine residues Ser473 C-terminal hydrophobic motifs human cancers dephosphorylates dephosphorylation reduces activity apoptosis apoptotic colon glioblastomas lines tumors brain 2.594488950276
10735 Phthalazinone pyrazole Exclusive 880487-62-7 ≥98% 2011-07-27 18.433001841621 phthalazinone-pyrazole inhibitors inhibits inhibition auroras kinases cells cycle cancers centrosomes mitosis spindles cancers proliferation cells growth phosphorylation Auroroa-A Aurora-B Aurora-C A B C HCT116 HCT-116 Colo 116 HCT 116 Colo116 Colo-116 MCF7 MCF-7 MCF 7 18.433001841621
10012556 Phytomonic Acid 503-06-0 ≥98% 2008-09-04 5.445220994475 phytomonic-acid Lactobacillic Acid saturated fatty acids lactobacillus arabinosus cyclopropane ring cells membranes 5.445220994475
13326 Pifithrin-α 63208-82-2 ≥95% 2009-07-16 22.313909306856 pifithrin PFT-α p53 apoptosis DNA damage cyclin D1 C8 cells HUVECs endothelial cells dependent independent inactivator 22.313909306856
10748 Pifithrin-μ 64984-31-2 ≥98% 2011-06-20 17.671159153388 pifithrin 2-Phenylethynesulfonamide; PFT-μ p53 apoptosis Bcl-xL Bcl-2 mitochondria inhibitors nutlin heat shock proteins 70 HSP70 PES PAS pifithrin-mu pifithrin mu PFTμ PFTu 2-phenylacetylenylsulfonamide 2-phenylacetylenesulfonamide BclxL Bc12 17.671159153388
10728 PIT-1 53501-41-0 ≥98% 2011-03-25 7.100276243093 pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domains cancers inhibitors Akt PDK1 PTENs proteins binding pituitary-specific transcription factors pit-1 pituitary-specific pit 1 GHF-1 GHF 1 pit-oct-unc pit oct unc POU growth hormones 7.100276243093
10007839 PLC thio-PIP2 (sodium salt) - >98% 2006-01-18 15.523573401736 plc-thio-pip2-sodium-salt phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono 1012328-27-6 15.523573401736
11004 Podoplanin Monoclonal Antibody (Clone NZ-1.2) - 2011-08-05 0E-12 podoplanin-monoclonal-antibody-clone-nz-1-2 gp38; T1A; Aggrus mucin glycoproteins T1A gp38 aggrus tumors cells ligands CLEC-2 metastases tissues Th17 CD4+ humans PBMC antibodies 0E-12
11005 Podoplanin Monoclonal Antibody (Clone pmab-1) - 2011-08-05 0E-12 podoplanin-monoclonal-antibody-clone-pmab-1 T1A; Aggrus; gp38 gp38 glycoproteins tissues lymphatic endothelial cells tumors lymphangiogenesis Th17 autoimmune diseases antibodies myelin antigens migration inflammation 0E-12
14244 PP1 (Src Inhibitor) 172889-26-8 ≥98% 2013-03-04 12.936270718232 pp1-src-inhibitor EI 275; AGL 1872 347193-60-6 AGL1872 AGL-1872 EI275 EI-275 PTK inhibitors Src kinases tyrosine cancers antitumors TGF-β TGF β TGF-.beta. TGF.beta. TGF-b TGF-beta TGFb TGFbeta TGFs ATPs Src protein p56 p59 CD3 CD-3 CD 3 inhibits inhibition 12.936270718232
13198 PP2 172889-27-9 ≥98% 2010-09-20 23.264940805051 pp2 AGL 1879 PTK inhibitors inhibits inhibition Src kinase T cells T-cells enzymes AG1879 AG 1879 PP-2 PP 2 signalling tyrosine kinases tyrosine focal Tyr 577 adhesion kinases AG-1879 AGL1879 AGL 1879 thaliana Proteins Arabidopsis Proteins Arabidopsis thaliana Arabidopsis thaliana Proteins Hemagglutinins Plant Thale Cress Proteins Plant Hemagglutinins Arabidopsis Proteins Agglutinins Plant Plant Agglutinins Proteins Plant Phytagglutinins Plant Proteins Lectins Plant Plant Lectins 23.264940805051
15595 PP3 New 5334-30-5 ≥98% 2014-03-06 0E-12 pp3 NSC 1401 PTK inhibitors inhibits inhibitions Src Kinase tyrosine kinases cancers antitumors negative controls inactive PP-3 PPs 3 three analog PP1 PP2 cell biology intracellular signals signaling NSC1401 NSC-1401 NSCs 1401 0E-12
13559 PRMT5 Polyclonal Antibody - 2009-07-24 1.926519337016 prmt5-polyclonal-antibody JBP1; Skb1HS; Protein Arginine Methyltransferase 7 proteins PRMTs signaling WB western immunoblotting blots ADMA blotting janus kinase-binding kinase binding fission yeast 1 1.926519337016
13558 PRMT6 Polyclonal Antibody - 2009-07-24 1.926519337016 prmt6-polyclonal-antibody Protein Arginine Methyltransferase 6 antibodies WB HeLa proteins western immunoblotting blots blotting 1.926519337016
13551 PRMT7 Polyclonal Antibody - 2009-07-24 1.712461632903 prmt7-polyclonal-antibody Protein Arginine Methyltransferase 7 PRMTs antibodies proteins western blotting immunoblotting blots SRC steroid receptor co-activator coactivator GRIP-1 GRIP1 WB 1.712461632903
14289 Propidium Iodide 25535-16-4 ≥90% 2013-04-24 4.206574585635 propidium-iodide PI 36015-30-2 cells fluorescents probes fluorescence cells biology apoptosis viability deaths membranes impermeant penetrates dead damaged multicolor fluorescent techniques counterstains binds DNA RNA bindings microscopy cytometry FC diiodide viable deoxy ribonucleic acids intercalates intercalating bases flow 4.206574585635
9000376 Prostaglandin E2-PEG11-biotin Exclusive - ≥98% 2009-05-13 81.263075506445 prostaglandin-e2-peg11-biotin PGE2-PEG11-biotin prostaglandins E2 PGE2 linker spacer biotins biotinamides receptors ligands fatty acids binding proteins avidin PEGlycated PGE2-biotin PGs biotinylated 81.263075506445
10011237 Protein Phosphatase 2A C subunit (human recombinant; L309 deletion) Exclusive - 2008-07-17 36.582467771639 protein-phosphatase-2a-c-subunit-human-recombinant-l309-deletion PP2A L309; PP2A Δ309; PP2A Cα proteins phosphatases serine threonine cellular tumors enzyme kinetics regulations substrates phosphorylasion PP2As octahistidine-tag streptactin-tag active 36.582467771639
9000660 PtdIns-(1,2-dihexanoyl) (sodium salt) Exclusive - ≥98% 2010-09-24 10.662501428843 ptdins-1-2-dihexanoyl-sodium-salt 1051393-51-1 phosphatidylinositols triphosphates cells signaling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PLS 10.662501428843
10008099 PtdIns-(1,2-dioctanoyl) (sodium salt) 899827-36-2 ≥98% 2006-01-17 11.043305051302 ptdins-1-2-dioctanoyl-sodium-salt DOPI; Phosphatidylinositol C-8 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 105172-95-0 11.043305051302
10007710 PtdIns-(1,2-dipalmitoyl) (ammonium salt) Exclusive 34290-57-8 ≥98% 2005-12-30 23.590748535731 ptdins-1-2-dipalmitoyl-ammonium-salt Phosphatidylinositol C-16; DPPI phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 28366-80-5 23.590748535731
10007764 PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) - ≥98% 2005-12-30 21.407183945401 ptdins-3-4-5-p3-1-2-dioctanoyl-sodium-salt DOPI-3,4,5-P3; Phosphatidylinositol-3,4,5-trisphosphate phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP3 mono PIPs 167465-37-4 21.407183945401
9000414 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt) Exclusive - ≥99% deuterated forms (d1-d62) 2009-09-25 11.436391354413 ptdins-3-4-5-p3-1-2-dipalmitoyl-d62-sodium-salt DPPI-3,4,5-P3-d62; Phosphatidylinositol-3,4,5-trisphosphate C-16-d62 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids PIPs phosphatidylinositols triphosphates phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP3 mono di 11.436391354413
9000829 PtdIns-(3,4,5)-P3 (1-stearoyl, 2-docosahexaenoyl) (sodium salt) Exclusive - 98% 2010-08-23 29.290096685082 ptdins-3-4-5-p3-1-stearoyl-2-docosahexaenoyl-sodium-salt phospholipids phospholipases C PLC inositols tetrakisphosphates IP4 diacylglycerols DAG calcium pleckstrin homology domains 29.290096685082
10009531 PtdIns-(3,4,5)-P3-biotin (sodium salt) 1415684-80-8 ≥98% 2007-01-16 10.625457335789 ptdins-3-4-5-p3-biotin-sodium-salt PIP3-biotin; Phosphatidylinositol-3,4,5-triphosphate C-8-biotin phosphatidylinositols triphosphates phospholipids phophorylation intracellular signals transduction PIP2 biotinimides dioctanoyl PTEN PI3k affinity probes ligands detection transmembranes receptors nucleic acids proteins binding kinases biotins biotinylated 732974-95-7 10.625457335789
10010383 PtdIns-(3,4,5)-P3-fluorescein (ammonium salt) Exclusive - ≥95% 2008-08-13 20.189017363852 ptdins-3-4-5-p3-fluorescein-ammonium-salt PIPs PIP3-fluorescein fluorescent PI3K PTENs phosphatidylinositol phosphates phosphorylated kinases binding proteins PIPs 20.189017363852
10007759 PtdIns-(3,4)-P2 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 10.039969702370 ptdins-3-4-p2-1-2-dihexanoyl-sodium-salt DHPI-3,4-P2; Phosphatidylinositol-3,4-bisphosphate C-6 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 1005032-08-5 10.039969702370
10008400 PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) - ≥98% 2006-11-16 13.604690607734 ptdins-3-4-p2-1-2-dioctanoyl-sodium-salt DOPI-3,4-P2; Phosphatidylinositol-3,4-bisphosphate C-8 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 204858-54-8 13.604690607734
10007763 PtdIns-(3,5)-P2 (1,2-dioctanoyl) (sodium salt) - ≥98% 2005-12-30 22.340749539595 ptdins-3-5-p2-1-2-dioctanoyl-sodium-salt DOPI-3,5-P2; Phosphatidylinositol-3,5-bisphosphate C-8 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 752191-34-7 22.340749539595
10005616 PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 (ammonium salt) - ≥99% deuterated forms (d1-d62) 2005-12-30 10.607934539414 ptdins-3-p1-1-2-dipalmitoyl-d62-ammonium-salt Phosphatidylinositol-3-phosphate C16-d62; DPPI-3-P-d62 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP1 triphosphates mono 10.607934539414
10007762 PtdIns-(4,5)-P2 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 32.821635013811 ptdins-4-5-p2-1-2-dihexanoyl-sodium-salt DHPI-4,5-P2; Phosphatidylinositol-4,5-bisphosphate C-6 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 1005032-09-6 32.821635013811
10008115 PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) - ≥98% 2006-01-17 19.134154453209 ptdins-4-5-p2-1-2-dipalmitoyl-sodium-salt DPPI-4,5-P2; Phosphatidylinositol-4,5-diphosphate C-16 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono 120595-88-2 19.134154453209
10005615 PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (sodium salt) - ≥99% deuterated forms (d1-d62) 2006-01-30 11.436391354413 ptdins-4-5-p2-1-2-dipamitoyl-d62-sodium-salt DPPI-4,5-P2-d62; Phosphatidylinositol-4,5-diphosphate C16-d62 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP2 triphosphates mono di 11.436391354413
10008159 PtdIns-(4,5)-P2-biotin (sodium salt) - ≥98% 2006-12-21 20.606104972376 ptdins-4-5-p2-biotin-sodium-salt Phosphatidylinositol-4,5-diphosphate C-8-biotin phosphatidylinositols diphosphates phospholipids phophorylation intracellular signals transduction PIP2 biotinimides dioctanoyl PTEN PI3k affinity probes ligands detection transmembranes receptors nucleic acids proteins binding kinases PIPs biotins biotinylated 20.606104972376
10010388 PtdIns-(4,5)-P2-fluorescein (ammonium salt) - ≥95% 2008-08-14 38.796804788213 ptdins-4-5-p2-fluorescein-ammonium-salt PIPs PIP2 fluoresceins fluorescent PI3K PTEN probes 38.796804788213
10007757 PtdIns-(4)-P1 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 10.032484405631 ptdins-4-p1-1-2-dihexanoyl-sodium-salt Phosphatidylinositol-4-phosphate C-6; DHPI-4-P1 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 10.032484405631
10007711 PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) 1246303-11-6 ≥97% 2005-12-30 10.032484405631 ptdins-4-p1-1-2-dioctanoyl-ammonium-salt Phosphatidylinositol-4-phosphate C-8; DOPI-4-P1 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 10.032484405631
10008050 PtdIns-(5)-P1 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 10.366900552486 ptdins-5-p1-1-2-dihexanoyl-sodium-salt DHPI-5-P1; Phosphatidylinositol-5-phosphate phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 10.366900552486
10007758 PtdIns-(5)-P1 (1,2-dioctanoyl) (ammonium salt) - ≥98% 2005-12-30 10.366900552486 ptdins-5-p1-1-2-dioctanoyl-ammonium-salt Phosphatidylinositol-5-phosphate C-8; DOPI-5-P1 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 291527-92-9 10.366900552486
10009746 PTEN (human recombinant) - ≥95% 2008-09-04 10.249005524862 pten-human-recombinant Phosphatase and Tensin Homology on Chromosome 10; MMAC1; Phosphatidylinositol 3-phosphatase; TEP1 proteins PTENs phosphatase homology tensin chromosomes enzymes lipids Sf21 cells recombinant N-terminal tumor suppressor cancers phosphoinositide hexahistidine His-tag His-tagged active 10.249005524862
13884 Puromycin (hydrochloride) 58-58-2 ≥98% 2012-10-24 11.795082872928 puromycin-hydrochloride CL 16536; CL 13900; NSC 3055; PDH 53-79-2 CL13900 CL-13900 CL16536 CL-16536 CL 16,536 CL13,900 NSC3055 NSC-3055 P 638 P638 P-638 dihydrochloride stylomycin antibiotics translation proteins synthesis tRNA cells culture inhibitors ribosome mRNA inhibits inhibitions aminonucleoside Streptomyces alboniger prokaryotes eukaryotes premature termination nascent polypeptide chains 11.795082872928
13294 Pyrrophenone 341973-06-6 ≥90% 2010-04-07 26.711412786109 pyrrophenone phospholipase A2 group IVA phospholipase A2 PLA2 cytosolic PLA2 cPLA2 arachidonic acid AA prostaglandins PG leukotrienes LT inhibitors PGE2 LTB4 blood secretory type PLA2 sPLA2 inflammation inhibition inhibits inflammatory Pyrrolidines 26.711412786109
700470 Pyruvate Assay Kit - 2010-11-03 62.176422200556 pyruvate-assay-kit Pyruvic Acid Assay Kit kits assays measures measurements acids cells cellular metabolic metabolism pathways glucose glucolysis oxygen dehydrogenases acetyl-CoA coenzymes A citric cycle Kreb's Krebs ATP adenosines triphosphates carbohydrates gluconeogenesis fatty acids dietary supplements weight loss exercise endurance antioxidants biochemical reactions lactate redox NAD+ NADH circulatory failures blood shock livers diseases congestive hearts failures diabetes mellitus thiamine deficiency disorders fluorescence-based fluorescent quantifying biological samples serum plasma urine saliva intracellular extracellular concentrations culture acetyls phosphates hydrogens peroxides H2O2 carbon dioxides CO2 ADHP 10-acetyl-3,7-dihydroxyphenoxazines resorufins 62.176422200556
13346 Rapamycin 53123-88-9 ≥95% 2009-10-21 65.769371252956 rapamycin Sirolimus immunosuppresssants transplants rejection inhibitors IL-2 lymphocytes B cells T FKBP12 mTOR mTORC1 cancer adipogenesis diabetes tuberous sclerosis cardiovascular diseases 65.769371252956
14501 RGD Peptide 114681-65-1 ≥95% 2013-06-17 0.108287292818 rgd-peptide H-Gly-Arg-Gly-Asp-Asn-Pro-OH; GRGDNP arginines glycines aspartate integrin extra cellulars matrix cells adhesions migrations growths differentiations apoptosis pro-caspase-3 pro caspases 3 procaspase three inhibitors inhibits inhibitions RGD-peptides peptides synthetics motifs arginine-glycine-aspartate s autoprocessing auto processing activations active integrin-ligands interactions biology clusters clusting signals signaling 0.108287292818
15359 RGDS Peptide New 91037-65-9 2014-02-03 0E-12 rgds-peptide H-Arg-Gly-Asp-Ser-OH; Fibronectin Inhibitor 1349520-​82-​6 inhibitors inhibits inhibitions vascular diseases peptides infectious signal transduction cells biology fibronectin tetra-peptide tetrapeptide tetra peptides fibrinogen α a alpha .alpha. von Willebrand factors thrombin bindings binds binders platelets integrins 0E-12
13204 Robotnikinin 1132653-79-2 ≥97% 2013-01-31 49.833992224268 robotnikinin sonic hedgehog Shh signaling development cancers Patched Ptch1 Smoothened Smo Gli2 Gli1 small molecule inhibitors inhibits inhibitions upstream up-stream up stream keratinocytes humans skins 49.833992224268
14339 Ruthenium Red 11103-72-3 2013-04-12 1.778851205692 ruthenium-red C.I. 77800; Ammoniated Ruthenium Oxychloride 1307-52-4 polycationic dyes sarcoplasmic reticulum Ca2+ release uptakes ryanodine receptors skeletal muscles cardiac glycoconjugates labeling labels inhibits inhibitors inhibitions blocks mitochondria prevents ryanodine-sensitive sensitive intracellular binds anionic markers cellular transports barriers functions C.I.77800 C.I.-77800 SR calcium cells surface negative binding sites 1.778851205692
14962 Ryanodine 15662-33-6 ≥98% 2013-09-10 36.956999783338 ryanodine 1361-01-9 1580-06-9 8047-13-0 15800-60-9 25800-57-1 insecticides plants alkaloids ryanodine receptors RyRs calcium channels calium signaling skeletal muscles cardiac sarcoplasmic reticulum SR contractions insecticidal conductance poisonous R. speciosa ligands organic isoforms nanomolar membranes contractions paralysis ryanex ryania ryanicide ryanodin rafflesia 36.956999783338
14187 S14161 883046-50-2 ≥99% 2013-02-12 1.033977900552 s14161 inhibitors inhibits inhibitions cells cycles biology cancers cyclins D1 D2 D3 PI3K tumors leukemia CDKs blood cancers D-cyclins S-14161 S 14161 phosphonositide 3-kinase PI3K G0/G1 phases induces inducer apoptosis myeloma leukemia hematopoietic transactivation 1.033977900552
10006616 S1P1 Blocking Peptide - 2005-03-02 44.291136543015 s1p1-blocking-peptide EDG-1; S1PR1; Sphingosine-1-phosphate Receptor 1 antibodies western blotting blots signaling signalling WB IHC ICC immunohistochemistry formalin-fixed paraffin-embedded sections immunocytochemistry receptors controls peptides proteins sphingosine-1-phosphate receptors G-protein-coupled S1P1/EDG-1 S1P2/EDG-5 S1P3/EDG-3 S1P4/EDG-6 S1P5/EDG-8 44.291136543015
10005228 S1P1 Polyclonal Antibody - 2005-02-09 34.386486187845 s1p1-polyclonal-antibody Sphingosine-1-phosphate Receptor 1; S1PR1; EDG-1 antisera antiserum antibodies proteins WB western blots blotting IHC ICC immunohistochemistry immunocytochemistry sphingosine-1-phosphate receptors G-protein-coupled S1P1/EDG-1 S1P2/EDG-5 S1P3/EDG-3 S1P4/EDG-6 S1P5/EDG-8 immunoblotting 34.386486187845
13488 S1P2 Polyclonal Antibody - 2009-08-24 34.725370165746 s1p2-polyclonal-antibody EDG-5; S1PR2; Sphingosine-1-phosphate Receptor 2 Western blots WB immunoblotting lysosphingolipid sphingosine 1-phosphate cells PTEN blotting EDG-5 EDG5 EDG 5 34.725370165746
10006373 S1P3 Polyclonal Antibody - 2005-08-23 46.785745856353 s1p3-polyclonal-antibody EDG-3; S1PR3; Sphingosine-1-phosphate Receptor 3 antibodies antisera antiserum WB western blots blotting ICC immunocytochemistry FACS flow cytometry sphingosine-1-phosphates GPCRs G-protein-coupled receptors S1P1 S1P2 S1P4 S1P5 edg-1 edg-5 edg-6 edg-8 couples coupling Gi/o-ERK G12/13-Rho axes mediates cell proliferation survival migration singalling events expressed tissues physiological functions receptors human mouse murine glycosylation N-terminal extracellular domains proteins migrates SDS-PAGE cerbral cortex liver heart immunoblotting 46.785745856353
13489 S1P4 Polyclonal Antibody - 2009-08-25 9.348158379373 s1p4-polyclonal-antibody EDG-6; S1PR4; Sphingosine-1-phosphate Receptor 4 Flow immunoblotting WB western blots immunoblotting ICC immunocytochemistry blotting 9.348158379373
13490 S1P5 Polyclonal Antibody - 2009-08-24 7.258839779005 s1p5-polyclonal-antibody Sphingosine-1-phosphate Receptor 5; S1PR5; EDG-8 Western blots WB immunoblotting S1P immunohistochemistry IHC paraffin blotting EDG-8 EDG8 EDG 8 7.258839779005
13664 S32826 1096770-84-1 ≥98% 2010-06-18 10.467448518332 s32826 Autotaxins lysophospholipase D lysophosphatidylcholine lysophosphatidic acids LPAs inhibitors src phosphatase 1B adipocytes plasma inhibited inhibition inhibits Esters, Phosphonic Acid Phosphonic Acid Esters Phosphonic Acids Phosphonates 10.467448518332
11914 SAG 912545-86-9 ≥98% 2012-11-02 53.176672805402 sag Smoothened Agonist 364590-63-6 receptors agonists hedgehogs signal transductions cells differentiation stem cells neuroscience genes expressions smoothened SMO GPCR chlorobenzothiophene inhibits inhibitions inhibitors signaling binds blocks cyclopamine cilia genes transcriptions lungs glucocorticoids pluripotent stems neural lineage cyclopamine 53.176672805402
14933 SANT 1 New 304909-07-7 ≥98% 2014-03-31 0E-12 sant-1 889672-85-9 receptors antagonists cells biology genes regulations neurosciences signal transductions stems cells research cancers smoothened SMOs SANTs SANT1 SANT-1 one 1 potent hedgehog HH antagonism Gli mediated transcriptions GPCR-like GPCR like Patched signaling regulates expressions antagonizing counteracts activations agonists SAG binding binds competes targets inactive cytoplasm primary cilium activated represses repress Gli-mediated 0E-12
10009557 SC-1 839707-37-8 ≥98% 2008-08-11 49.201436464088 sc-1 Pluripotin stem cells embryonic ras signal transduction ERK1 ERK2 ERK-1 ERK-2 PI3-kinase differentiation self-renewal selfrenewal SC1 SC 1 49.201436464088
10010267 SC-514 354812-17-2 ≥98% 2009-08-07 31.372394106814 sc-514 SC514 SC 514 inhibitors inhibits inhibitions IκB kinase IkB IKK2 NF-κB NFκB IL-1β IL1β genes expressions IL-6 IL6 IL-8 IL8 COX-2 COX2 iNOS LPS smooth muscles cells TLR2 TNF astrocytes 31.372394106814
14156 SD 169 1670-87-7 ≥97% 2013-02-15 14.783908839779 sd-169 5-Carbamoylindole inhibitors inhibits inhibitors signals transductions neurosciences diabetes cells biology signalings diabetes SD-169 SD169 SDs 169 ATP MAPK MAP kinases T cells nonobese diabetic NOD mice glucose homeostasis axonal regeneration sciatic nerve crush injury injuries gavage damage 14.783908839779
600260 Secreted Alkaline Phosphatase Reporter Gene Assay Kit (Luminescence) - 2010-04-27 18.449355432780 secreted-alkaline-phosphatase-reporter-gene-assay-kit-luminescence SEAP Reporter Gene kits assays measuring measurement phosphatases genes expression transfected cells culture mediums intracellular mRNA messenger ribonucleic acids proteins kinetics chromogenic substrates p-nitrophenyl para-nitrophenyl phosphates pNPP chemiluminescence chemiluminescent detections AP 18.449355432780
10010721 S-Glutathionylated Protein Detection Kit - 2009-06-09 94.595740040709 s-glutathionylated-protein-detection-kit PSSG Detection Assay assays kits measures measurements flow cytometry cytometer fluorescence microscopy GSH tripeptides gamma-glutamyl g-glutamyl .gamma.-glutamyl γ-glutamylcsteinylglyceines proteins sufhydryls reduction plasma tissues livers disulfides cells metabolic structural cytoskeletal signaling adduct antibodies Biotin-Switch method whole permeabilized avidin overlay analysis free-thiols enzymatic cleavages protein-S-glutathiones streptavidin-based glutathione 94.595740040709
13332 (S)-Glycyl-H-1152 (hydrochloride) 913844-45-8 ≥98% 2010-01-27 30.478863456984 -s-glycyl-h-1152-hydrochloride Rho Kinase Inhibitor IV Rho kinases ROCK-I p160ROCK ROCK-II G protein Rho cytoskeletons adhesions proliferation smooth muscles contraction stem cells inhibitors inhibition inhibited Fasudil hydrochloride ROCK IV h1152 h-1152 h 1152 30.478863456984
10007653 (S)-H-1152 (hydrochloride) 451462-58-1 ≥95% 2010-02-25 5.919242256822 -s-h-1152-hydrochloride Rho kinase ROCK cytoskeletal cytoskeleton smooth muscles contractions vasoconstriction neurons neurite inhibitors Y-27632 HA-1077 PKA PKC MLCK H1152 H 1152 inhibition inhibits 451462-58-1 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine H-7 H 7 h1152 h-1152 h 1152 5.919242256822
10007974 SLF Exclusive 195513-96-3 ≥98% 2006-04-14 17.634254143646 slf Synthetic Ligand of FKBP FK-506 synthetic binding proteins FKBP12 ligands immunosuppressants inhibits calcium/calmodulin-dependent phosphatases calcineurins T-cells cell-permeable analogs homodimers heterodimers dimerization ligand-specific fusion signaling monomers 10-atoms linkers Fas 17.634254143646
10823 SMAD2 Polyclonal Antibody - 2011-05-05 0E-12 smad2-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-2 SMAD 2 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 0E-12
10832 SMAD3 Polyclonal Antibody - 2011-05-03 0.345552486187 smad3-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-3 SMAD 3 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells signaling TGF-β MH1 domains DNA proteins SARA ECM apoptosis proliferation differentiation 0.345552486187
10838 SMAD4 Polyclonal Antibody - 2011-05-05 0.345552486187 smad4-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-4 SMAD 4 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 0.345552486187
10845 SMAD7 Polyclonal Antibody - 2011-05-05 0E-12 smad7-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 0E-12
10840 SMAD7 Polyclonal Antibody (azide-free) - 2011-05-05 0.345552486187 smad7-polyclonal-antibody-azide-free WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 0.345552486187
13891 (S)-nitro-Blebbistatin 856925-75-2 ≥98% 2013-10-09 68.841408925835 -s-nitro-blebbistatin S-(-)-7-Desmethyl-8-nitro Blebbistatin inhibitors inhibits inhibitions apoptosis cells biology cycles signals transduction cytoskeletals research nitroblebbistatin nitro blebbistatins permeable cell-permeable ATPases Mg-ATPase Mg blue lights imaging muscles myosin cytotoxic intermediates irradiation 68.841408925835
13121 Sodium Butyrate 156-54-7 ≥95% 2009-07-31 56.732605893186 sodium-butyrate Butyric Acid fatty acids short chains inhibitors inhibits inhibition histones deacetylases HDACs epigenetics growth arrest differentiation apoptosis cancers inflammation genes expressions pro-inflammatory proinflammatory cytokines IFN-γ IL-6 IFNγ IL6 IL-1β IL1β IFNg 56.732605893186
10012555 Sodium Hydrogen Sulfide (hydrate) 207683-19-0 ≥65% 2009-09-03 12.253224510296 sodium-hydrogen-sulfide-hydrate NaHS; NSC 158264; Sodium Hydrosulfide hydrogen sulfide H2S donor inflammation oxidative stress cardiocascular neurological neurons pulmonary leukocytes neutrophils pain 1310-76-5 64568-18-9 111883-06-8 16721-80-5 12.253224510296
10010146 Soluble Epoxide Hydrolase Polyclonal Antibody - 2008-03-03 7.910097497562 soluble-epoxide-hydrolase-polyclonal-antibody Cytosolic Epoxide Hydrolase (CEH); sEH; EPHX2; Epoxide Hydrolase 2 metabolism hypertension inflammation EpETrEs EETs DiHETrEs DHET inhibitors inhibit inhibitions epoxyeicosatrienoic acids eicosatrienoic WB western blots blotting immunoblotting 7.910097497562
10010466 SP 600125 129-56-6 ≥98% 2009-01-07 22.100441988950 sp-600125 NSC 75890; Pyrazolanthrone; 1PMV c-Jun cJun JNKs inhibitors inhibits inhibition reversible cell-permeable cells COX-2 COX2 MAP kinase MAPK genes expressions apoptosis autophagy differentiation IL-10 IL10 TNF-α TNFα IFN-γ IFNγ T-cells Tcells HeLa sp600125 22.100441988950
14918 Spermidine 124-20-9 ≥98% 2013-09-05 0E-12 spermidine natural polyamines putrescine decarboxylated S-adenosylmethionine dcSAM SAM dc-SAM dc synthases metabolism growth developments stress 0E-12
10006964 Sphingomyelinase Fluorometric Assay Kit - 2009-11-25 82.314677716390 sphingomyelinase-fluorometric-assay-kit SMase Fluorometric Assay Kit sphingomyelinases SMases hydrolases enzymes sphingolipids metabolisms DNases I superfamily sphingomyelins phosphorylcholines ceramides cells cellular stress cations lysosomal acids secreted zinc-dependent membrane-bound magnesium-dependent neutral cytosolic magnesium-independent neutral alkalines mutations ASM genes Type A B Niemann-Pick diseases physiological pathophysiological lysosomal digestion neuronal vascular ceramide-mediated signal transduction cytokine-induced apoptosis differentiation immune inflammatory lipoproteins aggregation vessel walls atherogenesis intracellular trafficking metabolism assays kits measures measuring measurements acidic activity tissues homogenates lysates serum blood saliva urine coupled enzymatic reactions oxidases betaine h2o2 hydrogen peroxides horseradish peroxidases HRPs 10-acetyl-3,7-dihydroxyphenozazine ADHP fluorescent fluorescence 82.314677716390
10006822 Sphingosine Kinase 1 Polyclonal Antibody - 2006-12-21 29.205461325966 sphingosine-kinase-1-polyclonal-antibody SPHK 1 proteins diseases antibodies antisera antiserum WB western blots blotting ICC immunocytochemistry sphingosines kinases enzymes sphingolipids metabolisms catalyzes phosphorylation sphingosine-1-phosphates cells proliferation death tissues kidneys livers spleen hearts platelets tumors cytosolic membranes amino acids post translational modifications SK1 SPK1 cancers immunoblotting 29.205461325966
10012201 Sphingosine Kinase 1 Polyclonal FITC Antibody Exclusive - 2008-06-06 3.984861878453 sphingosine-kinase-1-polyclonal-fitc-antibody SPHK 1 SPHK-1 metabolism sphingolipids phosphorylation sphingosine-1-phosphate cell proliferation death immunofluorescence IF flow cytometry FC western blots WB SPHKs blotting immunoblotting 3.984861878453
13339 SQ 22,536 17318-31-9 ≥95% 2012-05-09 45.740662983426 sq-22-536 NSC 53339 inhibitors inhibits inhibition adenylyl cyclases cAMP platelets iloprost vasorelaxation pulmonary veins vascular smooth muscles prostaglandins PGs PGE PGE1 E1 SQ 22536 SQ22,536 SQ-22,536 sq22536 45.740662983426
13337 ST638 107761-24-0 ≥98% 2010-09-21 21.766732438832 st638 tyrosine kinases inhibitors inhibits inhibition cell signaling signalling receptors tumor necrosis factor phosphorylation TNF-α phorbol myristate acetate PMA cardiac fibroblasts TNFα TNF α TNFalpha TNF.alpha. 21.766732438832
10625 StemRegenin 1 1227633-49-9 ≥98% 2012-10-11 177.725033763045 stemregenin-1 SR1 SR-1 SR 1 pluripotency hematopoietic stems cells HSC therapies CD34 CD133 differentiation HSC expansion antagonists aryl hydrocarbon receptors AHR CD-34 CD-133 CDs 34 133 stems regenin purine signaling differentiation 177.725033763045
14268 StemRegenin 1 (hydrochloride) - ≥98% 2013-03-06 174.824149785144 stemregenin-1-hydrochloride SR1 1227633-49-9 research receptors antagonists biology pluripotency hematopoietic stem cells HSC therapies CD34 CD133 differentiation HSC expansion aryl hydrocarbon AHR CD-34 CD-133 CDs 34 133 regenin SR-1 SR 1 purines derivatives 174.824149785144
13338 SU 6656 330161-87-0 ≥95% 2009-08-04 25.741731123388 su-6656 inhibitors Src kinases Src Yes Lyn Fyn cells growth development nervous system fibrosis cancers inhibits inhibition CNS SU6656 25.741731123388
600320 Sulfenylated Protein Cell-Based Detection Kit - 2013-03-07 141.292247464335 sulfenylated-protein-cell-based-detection-kit S-sulfenylated Protein Detection Assay; Protein Sulfenylation Detection Kit P-SOH kits measures measurements cell-based CBAs oxidative damages oxidized reactive oxygen species ROS cells cellular pathways diseases proteins modifications sulfenylations oxidations cysteine residues redox-sensitive sensors molecular switches activates activating deactivates deactivating states stress-induced cancers intracellular pathological conditions sulfenic acids formations GC/MS GC-MS gas chromatography-mass spectrometry HPLC high-performance liquid detectors detections Western blots blotting ELISA enzymes immunoassay immunosorbents assays bioorthogonal chemical reporters DAz-2 cell-permeables chemoselectives in situ acid-modified 141.292247464335
13159 Sunitinib Malate 341031-54-7 ≥98% 2009-04-15 25.142255371393 sunitinib-malate Sutent™; SU 11248 receptors tyrosine kinase inhibitors platelet-derived growth factor receptors PDGF PDGF-R vascular endothelial VEGF VEGF-R KIT FLT3 tumors cells angiogenesis stomach renal kidney cancer 25.142255371393
16860 Swainsonine 72741-87-8 ≥98% 2009-06-12 88.303142671434 swainsonine Tridolgosir Alkaloid N-linked glycoside hydrolases asparagine-linked glycoproteins glycoproteins inhibitor lysosomal α-mannosidase glycosidases Golgi α-mannosidase II N-linked glycosylation antiproliferative proliferation growth antimetastatic metastasis cancer α-mannosidase lysosomes oligosaccharides glycoproteins lysosomal storage disease toxicity locoism 88.303142671434
11590 Temsirolimus 162635-04-3 ≥98% 2013-05-01 23.132246777163 temsirolimus CCI-779; Torisel® cancers cells biology inhibitors inhibitions immunology signals transductions 343261-52-9 1034922-90-1 torisel Temsorolimus WAY-CCI 779 WAY-CCI-779 WAYCCI779 WAY CCI 779 CCI779 rapamycin immunosuppressants cytosolic FK-binding proteins 12 FKBP12 complexes mammals mammalian targets mTOR pathways Complex 1 I dihydroxymethyls propionic acids esters signalling signaling signals cycles arrests growth phases G1 G1-phase reduces reducing tumors angiogenesis synthesis VEGF cytostatic activity activities xenografts models humans nude mice mouse glioblastomas prostrates carcinomas pancreas pancreatic livers breasts medulloblastomas inhibitor-779 antitumors 23.132246777163
11190 Termitomycamide B 1254277-89-8 ≥97% 2012-01-31 0E-12 termitomycamide-b mushrooms extracts ER stress apoptosis endoplasmic reticulum neuroscience proteins misfolding Parkinson’s diseases Alzheimer’s prions fatty acids cells death termites termitomycamides Termitomyces titanicus Neuro2a 0E-12
11191 Termitomycamide E 1177258-62-6 ≥98% 2012-01-27 0E-12 termitomycamide-e 2'-Deoxotermitomycamide A mushrooms extracts ER stress apoptosis endoplasmic reticulum neuroscience proteins misfolding Parkinson’s diseases Alzheimer’s prions neuronal calcium homeostasis Termitomyces titanicus termites 0E-12
10007565 Tetradecyl Phosphonate 4671-75-4 ≥98% 2005-10-17 39.518421468035 tetradecyl-phosphonate pan-antagonists LPA receptors lysophosphatic acids lipids signalling molecules hydrolysis lysophospholipase D autotoxin signals GPCRs G-protein coupled LPA1/EDG-2 LPA2/EDG-4 LPA3/EDG-7 LPA4/GPR23 activates activation PPAR.gamma. peroxisomes proliferator-activated inhibits inhibition LPA-induced calcium mobilization activates reporter 39.518421468035
10522 Thapsigargin 67526-95-8 ≥97% 2011-09-23 43.129309392265 thapsigargin calcium, ATPases, sarco/endoplasmic calcium ATPases SERCAs cells signaling activation histamine cancers tumorigenesis inflammation reticula sarcoplasmic endoplasmic 43.129309392265
13083 ThioFluor 623 1004324-99-5 ≥98% 2009-03-16 22.569254143646 thiofluor-623 Fluorescent Thiol Probe thiols fluorophores cells permable cell-permeable 22.569254143646
11105 TNF Receptor-Associated Protein 1 (human recombinant) - ≥95% 2011-11-29 1.909116022100 tnf-receptor-associated-protein-1-human-recombinant Mitochondrial Heat Shock Protein 75 kDa; TRAP1; Hsp75; Hsp90L metabolism insulin non-insulin-dependent (type 2) diabetes mellitus glucose kinases tumors necrosis factor type 1 receptors-associated proteins TNFR-associated protein 1 ATP mitochondrial HSP90 heat shock ATPase cancers cardiomyocytes geldanamycin SNX-0723 SNX0723 SNX 0723 TNFR1 1.909116022100
700240 Total Phosphatidic Acid Fluorometric Assay Kit - 2009-08-24 56.659928966062 total-phosphatidic-acid-fluorometric-assay-kit PA Assay Kit assays kits measures fluorescence-based cells cellular phospholipids phosphatidate membranes storage de novo synthesis phospholipases PLD PLA hydrolysis phosphodiesters phosphatidylcholines PC phosphorylation diacylglycerol DAG DAGK lysophosphatidic LPA lysoPA-acyltransferase LPAAT phosphates phosphohydrolases LPPs intracellular signal transduction mammalian rapamycin mTOR signaling cycle progression growth disregulation human diseases cancers bacterial FKBP12 Raf-1 kinases sphingosines cAMP Adenosines 3',5' cyclic mononucleotides phosphodiesterases 4A1 translocation proteins PKC tyrosines SHP-1 guanine nucleotides Son of sevenless glycerol-3-phosphate oxidized oxidases hydrogen peroxides H2O2 peroxidases ADHP 10-acetyl-3,7-dihydroxyphenoxazines resorufin 56.659928966062
13340 TPEN 16858-02-9 ≥95% 2010-08-03 22.130462401603 tpen TPEDA zinc apoptosis hypoxic pulmonary vasoconstrictions cells proliferation differentiation caspases transition metals chelators cancers intracellular extracellular intracellular extra- intra- extra cellular ions concentrations vasoconstrictiors 22.130462401603
13719 TRPC4 Calcium Channel Monoclonal Antibody (Clone S77-15) - 2009-12-04 0.801104972375 trpc4-calcium-channel-monoclonal-antibody-clone-s77-15 Transient Receptor Potential Cation Channel antibodies western blots blotting immunoblotting WB ICC immunocytochemistry IP immunoprecipitation proteins smooth muscle endothelial cells nerves injuries injury c coupled c-coupled receptors 0.801104972375
13720 TRPM7 Ion Channel Ser/Thr Kinase Monoclonal Antibody (Clone S74-25) - 2009-12-04 1.602209944751 trpm7-ion-channel-ser-thr-kinase-monoclonal-antibody-clone-s74-25 antibodies WB western blots blotting immunoblotting immunoprecipitation IP immunocytochemistry ICC TRPs proteins channels ions ATPs calcium transient receptors potential 1.602209944751
13721 TRPV3 Channel Monoclonal Antibody (Clone S15-4) - 2009-12-04 0.801104972375 trpv3-channel-monoclonal-antibody-clone-s15-4 Transient Receptor Potential Cation Channel antibodies WB western blots blotting immunoblotting ICC immunocytochemistry immunoprecipitation IP channels ions chromosome 17 temperature sensation vasoregulation 0.801104972375
13723 Ubiquitin Monoclonal Antibody (Clone 6C11-B3) - 2009-12-04 3.522283400301 ubiquitin-monoclonal-antibody-clone-6c11-b3 antibodies western blots WB blotting immunoblotting ELISA ubiquitination inhibitors proteins IκBα signal transduction 3.522283400301
13724 Ubiquitin Polyclonal Antibody - 2009-12-04 5.458195002511 ubiquitin-polyclonal-antibody antibodies western blots WB blotting immunoblotting ELISA ubiquitination inhibitors proteins IκBα signal transduction 5.458195002511
10009152 Valinomycin 2001-95-8 >95% 2007-01-22 15.845248618785 valinomycin NSC 122023 Ionophore potassium ion antibiotic apoptosis cyclododecadepesipeptide Streptomyces efflux phosphatidylserine membrane translocation caspase-3 activation 15.845248618785
11724 Veratramine 60-70-8 ≥95% 2012-10-31 21.063647884040 veratramine NSC 17821; NSC 23880 10159-78-1 NSC17821 NSC-17821 NSC23880 NSC-23880 hedgehogs cyclopamine morphogenesis cancers tumors thrombosis platelet aggregation serotonins Hh tetratogenic steroidal alkaloid corn lily veratrum sp. analogs inhibits inhibitors inhibitions re-uptake reuptake uptake CNS signaling 21.063647884040
11762 Vinblastine (sulfate) 143-67-9 ≥95% 2013-02-08 4.810690607734 vinblastine-sulfate 29060LE; Exal; Rozevinsulfate; Vincaleukoblastinesulfate; Alkaban-AQ; NSC 49842; VLB; Velban®; Velsar inhibits inhibitors cells cycles biology cancers inhibitions vinca rosea alkaloid antimicrotubule drugs cancers hodgkins lymphoma non small nonsmall non-small cells lungs breasts heads necks testicular vincristine tubulin microtubule assembky cycles arrest chemotherapy regimens bleomycin methotrexate VBM combination chemotherapy therapy catharanthus roseus vinca C. V. madagascar periwinkle analogs M phase mitotic spindle L-cell L 29060-LE 29060 LE alkaban AQ NSC-49842 NSC49842 velban 4.810690607734
13206 VU0155069 - ≥95% 2009-09-03 19.444397743725 vu0155069 CAY10593 inhibitors inhibits inhibitions phospholipases D PLD PLD1 PLD2 phosphatidic acids PAs chemotaxis cells migration cancers breast lines tumors trans well assays 1130067-06-9 19.444397743725
10955 VU0359595 New 1246303-14-9 ≥95% 2013-12-02 46.424005293211 vu0359595 ML-270; CID-53361951 1246303-14-9 molecular library initiative agonists CID-53361951 CID53361951 CIDs 53361951 ML270 MLs 270 ML-270 PLD1 phophoslipases D inhibitors PLDs PLD-1 VUs 0359595 VU-0359595 inhibits inhibitions PLs phosphatidic acids isoforms binds binding binders allosteric sitesselective cell biology intracellular signaling transductions 46.424005293211
14277 W-13 (hydrochloride) 88519-57-7 ≥98% 2013-04-24 35.123878809749 w-13-hydrochloride 81705-04-6 signals transductions kinases inhibitors inhibits inhibitions cells biology calmodulins proliferations W-7 antagonists cancers calcium signaling CAM W7 W13 Ws 7 13 W-13 HCl naphthalenesulfonamides derivatives Ca2+ enzymes potent Ca2+/calmodulin-regulated regulateds activity activities 35.123878809749
14271 W-5 (hydrochloride) 61714-25-8 ≥98% 2013-03-12 19.072420246212 w-5-hydrochloride 79458-81-4 biology kinases signals transductions calmodulin cells proliferation W-7 antagonists cancers calcium signalings CAM control W5 W7 Ws 5 7 binds binding inhibits inhibitors inhibitions enzymes low affinity 19.072420246212
15047 Wiskostatin 253449-04-6 ≥98% 2013-09-25 0.885123966942 wiskostatin cytoskeletal researchs neurosciences cells biology WASPs wiskott-aldrich wiskott Aldrich syndromes proteins cell-permeable cells permeable inhibitors inhibits inhibitions neural n-WASPs GTPase-binding GTPase-binding binds binder Cdc42 Cdc-42 Cdc 42 PIP2 phosphatidylinositol 4,5-bisphosphate transports endocytosis neurological developments regulates actins cytoskeletons Arp2/3 complex Arp 2/3 cellular processes phagocytosis motility membranes trafficking wiskostatin selectives activations domains 0.885123966942
11352 Withaferin A 5119-48-2 ≥95% 2012-07-31 2.146408839779 withaferin-a NSC 101088; NSC 273757 NSC101088 NSC-101088 NSC273757 NSC-273757 5196-55-4 22848-77-7 47738-04-5 1246849-97-7 vimentin epithelial-mesenchymal transitions metastasis cancers cells aggregation intermediates filaments apoptosis anti-tumors angiogenesis peripherin neurofilament-triplet proteins keratin microtubules actin microfilaments epithelial mesenchymal neurofilament triplet Withania somnifera W. somnifera 2.146408839779
13671 Wortmannin-Rapamycin Conjugate Exclusive - ≥98% 2010-05-11 13.253563535911 wortmannin-rapamycin-conjugate phosphoinositide 3-kinases PI3K kinases three 3 mammalian targets rapamycins mTOR cancers inhibitors inhibits inhibitions TORC1 TORCs TORC-1 1 one prodrugs pro-drugs linkers linkage HT29 HT-29 colon tumors A498 A-498 As 498 renal tumors VEGF bevacizumab 13.253563535911
10008883 WST-1 Cell Proliferation Assay Kit - 2006-09-07 61.031719780073 wst-1-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements cancers cell-based assay cell based assay cba 61.031719780073
10010199 WST-8 Cell Proliferation Assay Kit - 2007-09-11 50.162885539274 wst-8-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microwell plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 50.162885539274
13639 WZ811 55778-02-4 ≥95% 2010-03-22 5.825994475138 wz811 CXC chemokines receptors CXCR4 stromal cell-derived factor-1 SDF-1 CXCL12 hematopoietic stem cells chemotaxis lymphocytes growth metastasis cancers T cells HIV infection inhibitors antagonist cAMP Matrigel invasion breast cancer adenocarcinoma inhibition alpha-Aminotoluene alpha Aminotoluene Phenylmethylamine Benzylamines 5.825994475138
10010200 XTT Cell Proliferation Assay Kit - 2007-09-11 39.313835124910 xtt-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 39.313835124910
14919 XTT (sodium salt) 111072-31-2 2013-09-12 2.056237285370 xtt-sodium-salt 117038-70-7 tetrazolium dyes water-soluble formazan colorimetric assays cells proliferation cytotoxicity apoptosis impermeable negatively charged NADH electrons mediators tetrazolium derivatives 2.056237285370
13246 YM-58483 223499-30-7 ≥98% 2009-11-16 10.337182320442 ym-58483 BTP 2 calcium channels leukocytes leukotrienes eicosanoids inflammation asthma allergy IL-2 IL-4 lymphocytes eosinophils NF-AT CRACs CysLTs interleukin-4 BTP2 BTP-2 CysLT 10.337182320442
15122 Zinpyr-1 New 288574-78-7 ≥90% 2013-11-04 16.455555555556 zinpyr-1 ZP-1 fluorescein fluorescents probes Zinc Zn2+ cells metabolism neurosciences zinpry zinpry1 cell-permeable permeable fluorescein-based based biology 16.455555555556
13601 ZM 447439 331771-20-1 ≥98% 2010-08-03 13.960092081031 zm-447439 auroras A B C kinases mitosis cytokinesis centromere inhibitors inhibits inhibition cancers Benzamides 13.960092081031
16837 β-Carotene 7235-40-7 ≥95% 2010-08-20 5.775013812154 -carotene Lucarotin; Provatene; Solatene; KPMK; Food Orange 5; Provitamin A; NSC 62794 vitamins A antioxidant retinol retinoic acids vision bone growth receptors RAR cell differentiation 116-32-5 31797-85-0 lucaratin lurotin provatenol serlabo βCarotene β Carotene b-carotene carotaben b bcarotene retinol 5.775013812154
11133 Δ2-cis-Hexadecenoic Acid Exclusive 2825-68-5 ≥98% 2012-01-18 1.266482504604 -2-cis-hexadecenoic-acid quorum sensing myxobacteria autoinducers mono-unsaturated fatty acids bacteria soil marine freshwater cellular cells membranes autotrophic myxococcus 1.266482504604

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